COG6_PICST
ID COG6_PICST Reviewed; 799 AA.
AC A3LT37;
DT 10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT 24-JUL-2007, sequence version 2.
DT 25-MAY-2022, entry version 68.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE Short=COG complex subunit 6;
DE AltName: Full=Component of oligomeric Golgi complex 6;
GN Name=COG6; ORFNames=PICST_45600;
OS Scheffersomyces stipitis (strain ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL
OS Y-11545) (Yeast) (Pichia stipitis).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Debaryomycetaceae; Scheffersomyces.
OX NCBI_TaxID=322104;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 58785 / CBS 6054 / NBRC 10063 / NRRL Y-11545;
RX PubMed=17334359; DOI=10.1038/nbt1290;
RA Jeffries T.W., Grigoriev I.V., Grimwood J., Laplaza J.M., Aerts A.,
RA Salamov A., Schmutz J., Lindquist E., Dehal P., Shapiro H., Jin Y.-S.,
RA Passoth V., Richardson P.M.;
RT "Genome sequence of the lignocellulose-bioconverting and xylose-fermenting
RT yeast Pichia stipitis.";
RL Nat. Biotechnol. 25:319-326(2007).
CC -!- FUNCTION: Acts as component of the peripheral membrane COG complex that
CC is involved in intra-Golgi protein trafficking. COG is located at the
CC cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles
CC and possibly a number of other membrane trafficking events (By
CC similarity). {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
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DR EMBL; CP000498; ABN66000.2; -; Genomic_DNA.
DR RefSeq; XP_001384029.2; XM_001383992.1.
DR AlphaFoldDB; A3LT37; -.
DR SMR; A3LT37; -.
DR STRING; 4924.XP_001384029.2; -.
DR PRIDE; A3LT37; -.
DR EnsemblFungi; ABN66000; ABN66000; PICST_45600.
DR GeneID; 4838816; -.
DR KEGG; pic:PICST_45600; -.
DR eggNOG; KOG3758; Eukaryota.
DR HOGENOM; CLU_017837_0_0_1; -.
DR InParanoid; A3LT37; -.
DR OMA; IINMICP; -.
DR OrthoDB; 1370285at2759; -.
DR Proteomes; UP000002258; Chromosome 4.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017119; C:Golgi transport complex; IEA:InterPro.
DR GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IEA:InterPro.
DR GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR InterPro; IPR010490; COG6.
DR PANTHER; PTHR21506; PTHR21506; 1.
DR Pfam; PF06419; COG6; 1.
DR SMART; SM01087; COG6; 1.
PE 3: Inferred from homology;
KW Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW Transport.
FT CHAIN 1..799
FT /note="Conserved oligomeric Golgi complex subunit 6"
FT /id="PRO_0000339329"
SQ SEQUENCE 799 AA; 91067 MW; F89483A42FCE6ADF CRC64;
MDFVDFDSFS NDEITGEDNL PHPQPALSLP ITSNIETIGK RISSLNTITR SLLKFEGTDE
EEGESSSENA SKENELAQKY AQMSLNFLKK EETQHGSDGK IANGVDGKSY NDFEHSKATL
STRLSRVLND SLSETLLREI FSHLEDKYSS YDDSIDELIE PGVVGSMSRK KLRGKVENEL
IKNQSLVLKE YQPVIKQLKV VEDRLSKLND LNKVTNDNIE NKFKYSSEFN TKVKELNSEK
RLINLKKNLL INFKAKFTLN EYEEFVLDSG DINDEFFTVL KKAEEINANC SILLSIENPQ
LGLKIMSKSN HLINRSVERI INFTNKTLSN LYSLNSKARL RTLHQCMRYL KNKLNYFSNV
VNTFVDSRAK VLVDDFLSQI QGNLDSNGNV STFKRRSSSI SSETSSRPIY VSAHDPIRFI
GDLLAYVHSL VVNESDTIIS IFTFETSESE VEKKEFETII KDIIDKILKS LVKPVKSKVT
QIISAETKLS TSYSIFNLVE LYSMMFTKQL SDTSEVSIAL KSLVKASQDR LASIISNRLA
SIRTSNSAQL ELNLDLQPPE WIIEFYSDLL PILDQTTTDT IFNFTAEENE EFMKLLVDEP
IEIFFEHIGS NKIFESKKDQ LILKHNFLDL ILSKLLPITI VSDKVIEINE MINTLTQELT
QLQLEAILKE CGLYDYYNIV NMICPFSDDF FDTSIYEPIK ENQLYNKSEL LKINEIIQSY
IPNALLDIQS SLLKLNPPSI VNEVTTNASL EFVKYYGKLS QINSAFLQET FTWSDFEIAT
LLGVDEDYTE FIKLVANSG
