ID   COG6_SCLS1              Reviewed;         670 AA.
AC   A7ERK2;
DT   10-JUN-2008, integrated into UniProtKB/Swiss-Prot.
DT   11-SEP-2007, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 6;
DE            Short=COG complex subunit 6;
DE   AltName: Full=Component of oligomeric Golgi complex 6;
GN   Name=COG6; ORFNames=SS1G_07956;
OS   Sclerotinia sclerotiorum (strain ATCC 18683 / 1980 / Ss-1) (White mold)
OS   (Whetzelinia sclerotiorum).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Leotiomycetes;
OC   Helotiales; Sclerotiniaceae; Sclerotinia.
OX   NCBI_TaxID=665079;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 18683 / 1980 / Ss-1;
RX   PubMed=21876677; DOI=10.1371/journal.pgen.1002230;
RA   Amselem J., Cuomo C.A., van Kan J.A.L., Viaud M., Benito E.P., Couloux A.,
RA   Coutinho P.M., de Vries R.P., Dyer P.S., Fillinger S., Fournier E.,
RA   Gout L., Hahn M., Kohn L., Lapalu N., Plummer K.M., Pradier J.-M.,
RA   Quevillon E., Sharon A., Simon A., ten Have A., Tudzynski B., Tudzynski P.,
RA   Wincker P., Andrew M., Anthouard V., Beever R.E., Beffa R., Benoit I.,
RA   Bouzid O., Brault B., Chen Z., Choquer M., Collemare J., Cotton P.,
RA   Danchin E.G., Da Silva C., Gautier A., Giraud C., Giraud T., Gonzalez C.,
RA   Grossetete S., Gueldener U., Henrissat B., Howlett B.J., Kodira C.,
RA   Kretschmer M., Lappartient A., Leroch M., Levis C., Mauceli E.,
RA   Neuveglise C., Oeser B., Pearson M., Poulain J., Poussereau N.,
RA   Quesneville H., Rascle C., Schumacher J., Segurens B., Sexton A., Silva E.,
RA   Sirven C., Soanes D.M., Talbot N.J., Templeton M., Yandava C., Yarden O.,
RA   Zeng Q., Rollins J.A., Lebrun M.-H., Dickman M.;
RT   "Genomic analysis of the necrotrophic fungal pathogens Sclerotinia
RT   sclerotiorum and Botrytis cinerea.";
RL   PLoS Genet. 7:E1002230-E1002230(2011).
CC   -!- FUNCTION: Acts as component of the peripheral membrane COG complex that
CC       is involved in intra-Golgi protein trafficking. COG is located at the
CC       cis-Golgi, and regulates tethering of retrograde intra-Golgi vesicles
CC       and possibly a number of other membrane trafficking events (By
CC       similarity). {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG6 family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH476630; EDN92094.1; -; Genomic_DNA.
DR   RefSeq; XP_001591330.1; XM_001591280.1.
DR   AlphaFoldDB; A7ERK2; -.
DR   SMR; A7ERK2; -.
DR   STRING; 665079.A7ERK2; -.
DR   GeneID; 5487318; -.
DR   KEGG; ssl:SS1G_07956; -.
DR   InParanoid; A7ERK2; -.
DR   OMA; RFYQQIM; -.
DR   Proteomes; UP000001312; Unassembled WGS sequence.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IBA:GO_Central.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; IBA:GO_Central.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR010490; COG6.
DR   PANTHER; PTHR21506; PTHR21506; 2.
DR   Pfam; PF06419; COG6; 1.
DR   SMART; SM01087; COG6; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..670
FT                   /note="Conserved oligomeric Golgi complex subunit 6"
FT                   /id="PRO_0000339331"
FT   REGION          1..32
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   670 AA;  75472 MW;  84611023E1F983D7 CRC64;
     MTTDYFTRKQ SYSGFSDGAD SPGSPLASRT NPLSSKVTSV LSASYADSDI RDALSLLDKR
     GIQNTAETRR QLRLDVHREV IESNGDIIRE FGHVAEEASE LMKQQEQMQA KQELLNAFNA
     HFVMSDDDIA MLTSTAEPVN DRFFSILSRA KKIQNDCEIL LGTENQRLGL EIMEQTSKNI
     NGAFQKLYRW IQREFKTLNL ENPQISSSIR RALRVLAERP SLFQSCLDFF AEARENILSD
     GFYTALTGTT VGGDEDPSIK PIELVAHDPL RYVGDMLAWT HSATVGEREA LEVLFISDGD
     EIAKGIQAGL DSEPWNRIAE SEDEVGHFDG LKALNELVDR DVAGVARVLR QKIGQVIQSH
     EETIMAYKIA NLLNFYRGTF QRLLGDDSVL LDSLATLEES ALRQFRALMR DHITSLQAET
     QVAPPNLSPP DFLHEGLKQL TAIMKTYETS FTSPETREAG FEPILTEAFD PFMKGSENVA
     KDLSAPRSTI FTINCLLSAR ATLAPFDFTI SRVSQIKDTI EEHAATLIDH QYIFFLEKSA
     LQPLLQALSA TTDIRDHPVF QPASLIQASQ TLDDFLPSAL MDAMENLKDL QNSMLVRQIT
     EEAAEKFCDD FEKVEERLMK ADEEREESLD EKDGEPHHVR ALYPRTGGEI RVLLSIRIWN
     MFKTWRLEIT