COG7_ARATH
ID COG7_ARATH Reviewed; 836 AA.
AC Q9FGN0; A0A097PSW2; B1Q4S9; Q0WQF0;
DT 13-NOV-2019, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2001, sequence version 1.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Conserved oligomeric Golgi complex subunit 7 {ECO:0000303|PubMed:27448097};
DE Short=COG complex subunit 7 {ECO:0000303|PubMed:27448097};
DE AltName: Full=Component of oligomeric Golgi complex 7 {ECO:0000303|PubMed:27448097};
DE AltName: Full=Protein EMBRYO YELLOW {ECO:0000303|PubMed:18422605};
GN Name=COG7 {ECO:0000303|PubMed:27448097};
GN Synonyms=EYE {ECO:0000303|PubMed:18422605};
GN OrderedLocusNames=At5g51430 {ECO:0000312|Araport:AT5G51430};
GN ORFNames=MFG13.14 {ECO:0000312|EMBL:BAB09754.1};
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA], FUNCTION, AND DISRUPTION PHENOTYPE.
RX PubMed=18422605; DOI=10.1111/j.1365-2443.2008.01186.x;
RA Ishikawa T., Machida C., Yoshioka Y., Ueda T., Nakano A., Machida Y.;
RT "EMBRYO YELLOW gene, encoding a subunit of the conserved oligomeric Golgi
RT complex, is required for appropriate cell expansion and meristem
RT organization in Arabidopsis thaliana.";
RL Genes Cells 13:521-535(2008).
RN [2]
RP NUCLEOTIDE SEQUENCE [MRNA].
RX PubMed=25249442; DOI=10.1038/ncomms5956;
RA Zeng L., Zhang Q., Sun R., Kong H., Zhang N., Ma H.;
RT "Resolution of deep angiosperm phylogeny using conserved nuclear genes and
RT estimates of early divergence times.";
RL Nat. Commun. 5:4956-4956(2014).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RA Kaneko T., Katoh T., Asamizu E., Sato S., Nakamura Y., Kotani H.,
RA Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 5. XI.";
RL Submitted (APR-1999) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [5]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RA Totoki Y., Seki M., Ishida J., Nakajima M., Enju A., Kamiya A.,
RA Narusaka M., Shin-i T., Nakagawa M., Sakamoto N., Oishi K., Kohara Y.,
RA Kobayashi M., Toyoda A., Sakaki Y., Sakurai T., Iida K., Akiyama K.,
RA Satou M., Toyoda T., Konagaya A., Carninci P., Kawai J., Hayashizaki Y.,
RA Shinozaki K.;
RT "Large-scale analysis of RIKEN Arabidopsis full-length (RAFL) cDNAs.";
RL Submitted (JUL-2006) to the EMBL/GenBank/DDBJ databases.
RN [6]
RP IDENTIFICATION BY MASS SPECTROMETRY [LARGE SCALE ANALYSIS].
RX PubMed=22223895; DOI=10.1074/mcp.m111.015131;
RA Bienvenut W.V., Sumpton D., Martinez A., Lilla S., Espagne C., Meinnel T.,
RA Giglione C.;
RT "Comparative large-scale characterisation of plant vs. mammal proteins
RT reveals similar and idiosyncratic N-alpha acetylation features.";
RL Mol. Cell. Proteomics 11:M111.015131-M111.015131(2012).
RN [7]
RP INTERACTION WITH COG5 AND COG6, GENE FAMILY, AND NOMENCLATURE.
RX PubMed=27448097; DOI=10.1371/journal.pgen.1006140;
RA Tan X., Cao K., Liu F., Li Y., Li P., Gao C., Ding Y., Lan Z., Shi Z.,
RA Rui Q., Feng Y., Liu Y., Zhao Y., Wu C., Zhang Q., Li Y., Jiang L., Bao Y.;
RT "Arabidopsis COG complex subunits COG3 and COG8 modulate golgi morphology,
RT vesicle trafficking homeostasis and are essential for pollen tube growth.";
RL PLoS Genet. 12:E1006140-E1006140(2016).
CC -!- FUNCTION: Required for normal Golgi function (PubMed:18422605).
CC Necessary for embryo development and pigmentation, especially for the
CC expansion of cells and organs, and for the formation of the organized
CC shoot apical meristem (SAM) (PubMed:18422605). Probably involved in the
CC generation of the extra-cellular matrix (PubMed:18422605).
CC {ECO:0000269|PubMed:18422605}.
CC -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC composed of eight different subunits and is required for normal Golgi
CC morphology and localization (Probable). Interacts with COG5 and COG6
CC (PubMed:27448097). {ECO:0000269|PubMed:27448097,
CC ECO:0000305|PubMed:27448097}.
CC -!- SUBCELLULAR LOCATION: Golgi apparatus membrane
CC {ECO:0000250|UniProtKB:P83436}; Peripheral membrane protein
CC {ECO:0000250|UniProtKB:P83436}.
CC -!- DISRUPTION PHENOTYPE: Abnormal coloration and morphology of embryos
CC leading to bushy plants, with aberrant organization of the shoot apical
CC meristem (SAM) and unexpanded leaves with irregular phyllotaxy, as well
CC as small and round epidermal cells (PubMed:18422605). Disrupted
CC hydrophobic layers of epidermal cells (PubMed:18422605).
CC Mislocalization of Golgi proteins (e.g. ERD2) and altered size of the
CC Golgi apparatus (PubMed:18422605). {ECO:0000269|PubMed:18422605}.
CC -!- SIMILARITY: Belongs to the COG7 family. {ECO:0000305}.
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DR EMBL; AB429304; BAG15881.1; -; mRNA.
DR EMBL; KM400475; AIU51104.1; -; mRNA.
DR EMBL; AB025621; BAB09754.1; -; Genomic_DNA.
DR EMBL; CP002688; AED96080.1; -; Genomic_DNA.
DR EMBL; AK228749; BAF00649.1; -; mRNA.
DR RefSeq; NP_199956.1; NM_124522.4.
DR AlphaFoldDB; Q9FGN0; -.
DR IntAct; Q9FGN0; 2.
DR STRING; 3702.AT5G51430.1; -.
DR PaxDb; Q9FGN0; -.
DR PRIDE; Q9FGN0; -.
DR ProteomicsDB; 187189; -.
DR EnsemblPlants; AT5G51430.1; AT5G51430.1; AT5G51430.
DR GeneID; 835217; -.
DR Gramene; AT5G51430.1; AT5G51430.1; AT5G51430.
DR KEGG; ath:AT5G51430; -.
DR Araport; AT5G51430; -.
DR TAIR; locus:2163660; AT5G51430.
DR eggNOG; KOG4182; Eukaryota.
DR HOGENOM; CLU_006044_1_0_1; -.
DR InParanoid; Q9FGN0; -.
DR OMA; IFEYFHK; -.
DR OrthoDB; 280917at2759; -.
DR PhylomeDB; Q9FGN0; -.
DR PRO; PR:Q9FGN0; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; Q9FGN0; baseline and differential.
DR GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0017119; C:Golgi transport complex; IBA:GO_Central.
DR GO; GO:0009793; P:embryo development ending in seed dormancy; IMP:TAIR.
DR GO; GO:0007030; P:Golgi organization; IMP:TAIR.
DR GO; GO:0006886; P:intracellular protein transport; IEA:InterPro.
DR GO; GO:0048507; P:meristem development; IMP:TAIR.
DR GO; GO:0009933; P:meristem structural organization; IMP:TAIR.
DR GO; GO:0045053; P:protein retention in Golgi apparatus; IMP:TAIR.
DR GO; GO:0006890; P:retrograde vesicle-mediated transport, Golgi to endoplasmic reticulum; IBA:GO_Central.
DR GO; GO:0010016; P:shoot system morphogenesis; IMP:TAIR.
DR GO; GO:0009826; P:unidimensional cell growth; IMP:TAIR.
DR InterPro; IPR019335; COG7.
DR PANTHER; PTHR21443; PTHR21443; 1.
DR Pfam; PF10191; COG7; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Golgi apparatus; Membrane; Protein transport;
KW Reference proteome; Transport.
FT CHAIN 1..836
FT /note="Conserved oligomeric Golgi complex subunit 7"
FT /id="PRO_0000448529"
FT REGION 246..265
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 29..49
FT /evidence="ECO:0000255"
FT COILED 107..127
FT /evidence="ECO:0000255"
FT COMPBIAS 251..265
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT CONFLICT 284
FT /note="L -> R (in Ref. 1; BAG15881)"
FT /evidence="ECO:0000305"
FT CONFLICT 612
FT /note="A -> P (in Ref. 5; BAF00649)"
FT /evidence="ECO:0000305"
FT CONFLICT 724
FT /note="Missing (in Ref. 2; AIU51104)"
FT /evidence="ECO:0000305"
FT CONFLICT 825
FT /note="N -> S (in Ref. 1; BAG15881)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 836 AA; 92259 MW; A875BAE2F18F61BD CRC64;
MMLDLGPFSD EKFDAKRWVN SSCQARHPQD SLEKHLVDLE MKLQIASEEI GASLEEQSGG
ALLRVPRATR DVLRLRDDAV SLRGSVAGIL QKLKKAEGSS ADCIAALARV DNVKQRMEAA
YKTLQDAAGL TQLSSTVEDV FASGDLPRAA ETLASMRNCL SAVGEVAEFA NVRKQLEVLE
DRLEAMVQPR LTDALTYHKV DVAQDLRVIL IRIGRFKSLE LQYSKVRLKP IKQLWEDFDT
KQRANKLANE RSESQRLSSG DEFQSTSSQT SFASWLTSFY DELLLYLEQE WKWCMVAFPD
DYMTLVPKLL VETMGVLGAS FVSRLNLATG DAVPETKALA KGVMDLLSGD LPKGINIQTK
HLEALIELHN VTGSFARNIQ HLFAESELRI LIDTLKAVYS PFESFKQKYG KMERAILSSE
IAVVDLRGAV TRGVGAQGIE LSETVRRMEE SIPQVVVLLE AAVERCIGFT GGSEADELIL
ALDDIMLQYI SMLQETLKSL RVVCGVDGTG DGVGSKKDAS AEKRESSRKM DLTSNEEWSI
VQGALQILTV ADCLTSRSSV FEASLRATLA RLNSSLSISL FGTNLDHNLS HLKSEQTAGD
LSMAGRASMD VAAIRLVDVP EKAHKLLNLL EQSKDPRFHA LPLASQRVAA FADTVNELVY
DVLISKVRQR LGEVSRLPIW SSVEEQTAFP LPNFSSYPQS YVTSVGEYLL TLPQQLEPLA
EGISTNGDSN NEDAQFFATE WMFKVAEGAT ALYMDQLRGI QYISDRGAQQ LSVDIEYLSN
VLSALSMPIP PVLATFQTCL ATPRGELKDV MKSEAGNELD CPTANLVCKM RRISFD
