ID   COG8_BOVIN              Reviewed;         626 AA.
AC   Q2TBH9;
DT   01-JUL-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-JAN-2006, sequence version 1.
DT   03-AUG-2022, entry version 76.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 8;
DE            Short=COG complex subunit 8;
DE   AltName: Full=Component of oligomeric Golgi complex 8;
GN   Name=COG8;
OS   Bos taurus (Bovine).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC   Bovinae; Bos.
OX   NCBI_TaxID=9913;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC   STRAIN=Crossbred X Angus; TISSUE=Liver;
RG   NIH - Mammalian Gene Collection (MGC) project;
RL   Submitted (NOV-2005) to the EMBL/GenBank/DDBJ databases.
CC   -!- FUNCTION: Required for normal Golgi function. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC       composed of eight different subunits and is required for normal Golgi
CC       morphology and localization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG8 family. {ECO:0000305}.
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DR   EMBL; BC110177; AAI10178.1; -; mRNA.
DR   RefSeq; NP_001070535.1; NM_001077067.2.
DR   AlphaFoldDB; Q2TBH9; -.
DR   SMR; Q2TBH9; -.
DR   STRING; 9913.ENSBTAP00000002179; -.
DR   PaxDb; Q2TBH9; -.
DR   PRIDE; Q2TBH9; -.
DR   GeneID; 768007; -.
DR   KEGG; bta:768007; -.
DR   CTD; 84342; -.
DR   eggNOG; KOG2069; Eukaryota.
DR   InParanoid; Q2TBH9; -.
DR   OrthoDB; 1531483at2759; -.
DR   Proteomes; UP000009136; Unplaced.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; IEA:InterPro.
DR   GO; GO:0015031; P:protein transport; IEA:UniProtKB-KW.
DR   InterPro; IPR007255; COG8.
DR   InterPro; IPR016632; COG8_Metazoal_Plant.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   PANTHER; PTHR21311; PTHR21311; 1.
DR   Pfam; PF04124; Dor1; 1.
DR   PIRSF; PIRSF015415; COG8; 1.
DR   SUPFAM; SSF74788; SSF74788; 1.
PE   2: Evidence at transcript level;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..626
FT                   /note="Conserved oligomeric Golgi complex subunit 8"
FT                   /id="PRO_0000341686"
FT   REGION          580..626
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        580..600
FT                   /note="Pro residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   626 AA;  69782 MW;  F23DF9BB2AF7B961 CRC64;
     MAATATIPSS TTASATTTAT AAALGEVEDE GLLASLFRDR FPEAQWRERP DVGRYLRELS
     GSGLERLRRE PERLAEERAQ LLQQTRDLAF ANYKTFIRGA ECTERIHRLF GDVEESLGRL
     LDRLPSLQQS CRNFVKEAEE ISSNRRMNTL TLNRHTEILE ILEIPQLMDT CVRNSYYEEA
     LELAAYVRRL ERKYSSIPVI QGIVNEVRQS MQLMLSQLIQ QLRTNIQLPA CLRVIGFLRQ
     MDVFTEAELR VKFLQARDAW LRSILTAIPN DDPYFHITKT IEACRVHLFD IITQYRAIFS
     DEDPLLPPAM GEHMVNESAI FHGWVLQKVS QFLQVLETDL NRGIGSRLDS LLGQCMYFGL
     SFSRVGADFR GQLVPVFQQV AISTFQKAIQ EAVEKFQDEM NSYTLISTPA VLGSSALPAA
     APVTQPGTLQ PPMVLLDFPP LACFLNSILV AFNDLRLCCP VALAQEVTRA LEDALDKVTK
     VILAFHRAEE AAFSSGEQEL FVQFCTVFLE DLVPYLNRCL QVLFPPAQIA QTLGIPPTQL
     SKYGNLGHVN VSVVQEPLAF ILPKREPVFC LDKELVPELP APAPALPPNA PSPEPVTPVT
     PAVPDAGQEE VESAGPPQPD EPSAGI