ID   COG8_SCHPO              Reviewed;         378 AA.
AC   Q96WW5; O13603;
DT   16-DEC-2008, integrated into UniProtKB/Swiss-Prot.
DT   22-SEP-2009, sequence version 2.
DT   25-MAY-2022, entry version 99.
DE   RecName: Full=Conserved oligomeric Golgi complex subunit 8;
DE            Short=COG complex subunit 8;
DE   AltName: Full=Component of oligomeric Golgi complex 8;
GN   Name=cog8; ORFNames=pi008, SPBC11B10.03;
OS   Schizosaccharomyces pombe (strain 972 / ATCC 24843) (Fission yeast).
OC   Eukaryota; Fungi; Dikarya; Ascomycota; Taphrinomycotina;
OC   Schizosaccharomycetes; Schizosaccharomycetales; Schizosaccharomycetaceae;
OC   Schizosaccharomyces.
OX   NCBI_TaxID=284812;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=10620777;
RX   DOI=10.1002/(sici)1097-0061(20000115)16:1<71::aid-yea505>3.0.co;2-5;
RA   Machida M., Yamazaki S., Kunihiro S., Tanaka T., Kushida N., Jinno K.,
RA   Haikawa Y., Yamazaki J., Yamamoto S., Sekine M., Oguchi A., Nagai Y.,
RA   Sakai M., Aoki K., Ogura K., Kudoh Y., Kikuchi H., Zhang M.Q., Yanagida M.;
RT   "A 38 kb segment containing the cdc2 gene from the left arm of fission
RT   yeast chromosome II: sequence analysis and characterization of the genomic
RT   DNA and cDNAs encoded on the segment.";
RL   Yeast 16:71-80(2000).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=972 / ATCC 24843;
RX   PubMed=11859360; DOI=10.1038/nature724;
RA   Wood V., Gwilliam R., Rajandream M.A., Lyne M.H., Lyne R., Stewart A.,
RA   Sgouros J.G., Peat N., Hayles J., Baker S.G., Basham D., Bowman S.,
RA   Brooks K., Brown D., Brown S., Chillingworth T., Churcher C.M., Collins M.,
RA   Connor R., Cronin A., Davis P., Feltwell T., Fraser A., Gentles S.,
RA   Goble A., Hamlin N., Harris D.E., Hidalgo J., Hodgson G., Holroyd S.,
RA   Hornsby T., Howarth S., Huckle E.J., Hunt S., Jagels K., James K.D.,
RA   Jones L., Jones M., Leather S., McDonald S., McLean J., Mooney P.,
RA   Moule S., Mungall K.L., Murphy L.D., Niblett D., Odell C., Oliver K.,
RA   O'Neil S., Pearson D., Quail M.A., Rabbinowitsch E., Rutherford K.M.,
RA   Rutter S., Saunders D., Seeger K., Sharp S., Skelton J., Simmonds M.N.,
RA   Squares R., Squares S., Stevens K., Taylor K., Taylor R.G., Tivey A.,
RA   Walsh S.V., Warren T., Whitehead S., Woodward J.R., Volckaert G., Aert R.,
RA   Robben J., Grymonprez B., Weltjens I., Vanstreels E., Rieger M.,
RA   Schaefer M., Mueller-Auer S., Gabel C., Fuchs M., Duesterhoeft A.,
RA   Fritzc C., Holzer E., Moestl D., Hilbert H., Borzym K., Langer I., Beck A.,
RA   Lehrach H., Reinhardt R., Pohl T.M., Eger P., Zimmermann W., Wedler H.,
RA   Wambutt R., Purnelle B., Goffeau A., Cadieu E., Dreano S., Gloux S.,
RA   Lelaure V., Mottier S., Galibert F., Aves S.J., Xiang Z., Hunt C.,
RA   Moore K., Hurst S.M., Lucas M., Rochet M., Gaillardin C., Tallada V.A.,
RA   Garzon A., Thode G., Daga R.R., Cruzado L., Jimenez J., Sanchez M.,
RA   del Rey F., Benito J., Dominguez A., Revuelta J.L., Moreno S.,
RA   Armstrong J., Forsburg S.L., Cerutti L., Lowe T., McCombie W.R.,
RA   Paulsen I., Potashkin J., Shpakovski G.V., Ussery D., Barrell B.G.,
RA   Nurse P.;
RT   "The genome sequence of Schizosaccharomyces pombe.";
RL   Nature 415:871-880(2002).
CC   -!- FUNCTION: Required for normal Golgi function. {ECO:0000250}.
CC   -!- SUBUNIT: Component of the conserved oligomeric Golgi complex which is
CC       composed of eight different subunits and is required for normal Golgi
CC       morphology and localization. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Golgi apparatus membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COG8 family. {ECO:0000305}.
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DR   EMBL; AB004534; BAA21385.2; -; Genomic_DNA.
DR   EMBL; CU329671; CAC37507.2; -; Genomic_DNA.
DR   RefSeq; NP_595623.2; NM_001021517.3.
DR   AlphaFoldDB; Q96WW5; -.
DR   SMR; Q96WW5; -.
DR   BioGRID; 276346; 1.
DR   STRING; 4896.SPBC11B10.03.1; -.
DR   MaxQB; Q96WW5; -.
DR   PaxDb; Q96WW5; -.
DR   EnsemblFungi; SPBC11B10.03.1; SPBC11B10.03.1:pep; SPBC11B10.03.
DR   GeneID; 2539796; -.
DR   KEGG; spo:SPBC11B10.03; -.
DR   PomBase; SPBC11B10.03; cog8.
DR   VEuPathDB; FungiDB:SPBC11B10.03; -.
DR   eggNOG; KOG2069; Eukaryota.
DR   HOGENOM; CLU_017968_4_1_1; -.
DR   InParanoid; Q96WW5; -.
DR   OMA; QIIYLCK; -.
DR   PhylomeDB; Q96WW5; -.
DR   PRO; PR:Q96WW5; -.
DR   Proteomes; UP000002485; Chromosome II.
DR   GO; GO:0000139; C:Golgi membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0017119; C:Golgi transport complex; ISO:PomBase.
DR   GO; GO:0006891; P:intra-Golgi vesicle-mediated transport; ISO:PomBase.
DR   GO; GO:0006886; P:intracellular protein transport; IC:PomBase.
DR   InterPro; IPR007255; COG8.
DR   InterPro; IPR016159; Cullin_repeat-like_dom_sf.
DR   PANTHER; PTHR21311; PTHR21311; 1.
DR   Pfam; PF04124; Dor1; 1.
DR   SUPFAM; SSF74788; SSF74788; 1.
PE   3: Inferred from homology;
KW   Golgi apparatus; Membrane; Protein transport; Reference proteome;
KW   Transport.
FT   CHAIN           1..378
FT                   /note="Conserved oligomeric Golgi complex subunit 8"
FT                   /id="PRO_0000356246"
SQ   SEQUENCE   378 AA;  44081 MW;  BA657BB96A98A934 CRC64;
     MDSIGDNVTE MDAFVRDLTM KPYAELEKRK AELHAQKLKL VQKRQQLLRD NYNVLVDYAR
     NQDAFYQLLE NSRHDFKELV LHTNQLYEPV KRSQNFLTSI SEHYRDAKLM HQVQPQLSSI
     LELPELMNAC IERNYFSETL EFQALAYRLK DRFGTNSIIQ ELITQVETLV VKLTEKLILQ
     LQKPLKLYSL IKVVTYLRVT AKLSEAQLKY VFLYFSWKQL QTSLRNLVPL LDYNNPELYL
     RRYIQVIRDR AFSLLFQYQS VFGESSNDRL NAAGTVDIPN STSTSASPFE MDPEGFNNFG
     QNILSSFVRK LQLEICYVLQ KFMPNVKDST SKFSLLLQLY YCNQSLTKVG TDISIPLSKI
     LGSEWLEMIH SQSSEKQA