ID   COHE_ECOLI              Reviewed;         224 AA.
AC   P75974;
DT   01-JUN-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   03-AUG-2022, entry version 132.
DE   RecName: Full=Prophage repressor CohE {ECO:0000305};
DE   AltName: Full=Putative lambdoid prophage e14 repressor protein C2;
GN   Name=cohE; Synonyms=ymfK; OrderedLocusNames=b1145, JW1131;
OS   Escherichia coli (strain K12).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=83333;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=8905232; DOI=10.1093/dnares/3.3.137;
RA   Oshima T., Aiba H., Baba T., Fujita K., Hayashi K., Honjo A., Ikemoto K.,
RA   Inada T., Itoh T., Kajihara M., Kanai K., Kashimoto K., Kimura S.,
RA   Kitagawa M., Makino K., Masuda S., Miki T., Mizobuchi K., Mori H.,
RA   Motomura K., Nakamura Y., Nashimoto H., Nishio Y., Saito N., Sampei G.,
RA   Seki Y., Tagami H., Takemoto K., Wada C., Yamamoto Y., Yano M.,
RA   Horiuchi T.;
RT   "A 718-kb DNA sequence of the Escherichia coli K-12 genome corresponding to
RT   the 12.7-28.0 min region on the linkage map.";
RL   DNA Res. 3:137-155(1996).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / MG1655 / ATCC 47076;
RX   PubMed=9278503; DOI=10.1126/science.277.5331.1453;
RA   Blattner F.R., Plunkett G. III, Bloch C.A., Perna N.T., Burland V.,
RA   Riley M., Collado-Vides J., Glasner J.D., Rode C.K., Mayhew G.F.,
RA   Gregor J., Davis N.W., Kirkpatrick H.A., Goeden M.A., Rose D.J., Mau B.,
RA   Shao Y.;
RT   "The complete genome sequence of Escherichia coli K-12.";
RL   Science 277:1453-1462(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=K12 / W3110 / ATCC 27325 / DSM 5911;
RX   PubMed=16738553; DOI=10.1038/msb4100049;
RA   Hayashi K., Morooka N., Yamamoto Y., Fujita K., Isono K., Choi S.,
RA   Ohtsubo E., Baba T., Wanner B.L., Mori H., Horiuchi T.;
RT   "Highly accurate genome sequences of Escherichia coli K-12 strains MG1655
RT   and W3110.";
RL   Mol. Syst. Biol. 2:E1-E5(2006).
CC   -!- MISCELLANEOUS: This protein is part of the e14 prophage present on the
CC       genomes of E.coli K12 MG1655 and W3110.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; U00096; AAC74229.1; -; Genomic_DNA.
DR   EMBL; AP009048; BAA35971.1; -; Genomic_DNA.
DR   PIR; F64859; F64859.
DR   RefSeq; NP_415663.1; NC_000913.3.
DR   RefSeq; WP_000848748.1; NZ_CP047127.1.
DR   AlphaFoldDB; P75974; -.
DR   DIP; DIP-12721N; -.
DR   STRING; 511145.b1145; -.
DR   MEROPS; S24.A20; -.
DR   jPOST; P75974; -.
DR   PaxDb; P75974; -.
DR   PRIDE; P75974; -.
DR   EnsemblBacteria; AAC74229; AAC74229; b1145.
DR   EnsemblBacteria; BAA35971; BAA35971; BAA35971.
DR   GeneID; 66507846; -.
DR   GeneID; 945719; -.
DR   KEGG; ecj:JW1131; -.
DR   KEGG; eco:b1145; -.
DR   PATRIC; fig|511145.12.peg.1187; -.
DR   EchoBASE; EB3997; -.
DR   eggNOG; COG1974; Bacteria.
DR   HOGENOM; CLU_066192_1_3_6; -.
DR   InParanoid; P75974; -.
DR   OMA; DEEATIC; -.
DR   PhylomeDB; P75974; -.
DR   BioCyc; EcoCyc:G6589-MON; -.
DR   PRO; PR:P75974; -.
DR   Proteomes; UP000000318; Chromosome.
DR   Proteomes; UP000000625; Chromosome.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   CDD; cd06529; S24_LexA-like; 1.
DR   InterPro; IPR039418; LexA-like.
DR   InterPro; IPR036286; LexA/Signal_pep-like_sf.
DR   InterPro; IPR015927; Peptidase_S24_S26A/B/C.
DR   Pfam; PF00717; Peptidase_S24; 1.
DR   SUPFAM; SSF51306; SSF51306; 1.
PE   4: Predicted;
KW   DNA-binding; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..224
FT                   /note="Prophage repressor CohE"
FT                   /id="PRO_0000149718"
SQ   SEQUENCE   224 AA;  25095 MW;  BBCD7C455C3573E3 CRC64;
     MKTIHDIRRS NARKLRDGVG GNSSFATMID REPTQTSRFM GDGATKNIGD SMARHIEKCF
     DLPVGWLDQE HQTTNITKKP DVSITNKQIT LVPVISWVQA GAWKEVGYSE VDLSTAETYP
     CPVPCGEMTY ILRVIGDSMI DEYRPGDMIF VDPEVPACHG DDVIALMHDT GETTFKRLIE
     DGTQRYLKAL NPNWPEPYIK INGNCSIIGT VIFSGKPRRY KIKA