COL12_ARATH
ID COL12_ARATH Reviewed; 364 AA.
AC Q9LJ44; C0SVC3;
DT 05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 22-SEP-2009, sequence version 2.
DT 03-AUG-2022, entry version 128.
DE RecName: Full=Zinc finger protein CONSTANS-LIKE 12;
GN Name=COL12; OrderedLocusNames=At3g21880; ORFNames=MEK6.3, MEK6_2;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10907853; DOI=10.1093/dnares/7.3.217;
RA Kaneko T., Katoh T., Sato S., Nakamura Y., Asamizu E., Tabata S.;
RT "Structural analysis of Arabidopsis thaliana chromosome 3. II. Sequence
RT features of the 4,251,695 bp regions covered by 90 P1, TAC and BAC
RT clones.";
RL DNA Res. 7:217-221(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Fujita M., Mizukado S., Seki M., Shinozaki K., Mitsuda N., Takiguchi Y.,
RA Takagi M.;
RT "ORF cloning and analysis of Arabidopsis transcription factor genes.";
RL Submitted (MAR-2009) to the EMBL/GenBank/DDBJ databases.
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12692345; DOI=10.1104/pp.102.016188;
RA Griffiths S., Dunford R.P., Coupland G., Laurie D.A.;
RT "The evolution of CONSTANS-like gene families in barley, rice, and
RT Arabidopsis.";
RL Plant Physiol. 131:1855-1867(2003).
CC -!- INTERACTION:
CC Q9LJ44; Q4PSE2: NFYC8; NbExp=4; IntAct=EBI-15192317, EBI-15191571;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00357}.
CC -!- SIMILARITY: Belongs to the CONSTANS family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=BAB02188.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; AP000739; BAB02188.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002686; AEE76562.1; -; Genomic_DNA.
DR EMBL; AB493626; BAH30464.1; -; mRNA.
DR RefSeq; NP_001319614.1; NM_001338552.1.
DR AlphaFoldDB; Q9LJ44; -.
DR SMR; Q9LJ44; -.
DR BioGRID; 7075; 7.
DR IntAct; Q9LJ44; 7.
DR STRING; 3702.AT3G21880.1; -.
DR PaxDb; Q9LJ44; -.
DR PRIDE; Q9LJ44; -.
DR EnsemblPlants; AT3G21880.1; AT3G21880.1; AT3G21880.
DR GeneID; 821743; -.
DR Gramene; AT3G21880.1; AT3G21880.1; AT3G21880.
DR KEGG; ath:AT3G21880; -.
DR Araport; AT3G21880; -.
DR TAIR; locus:2088748; AT3G21880.
DR eggNOG; ENOG502QSHH; Eukaryota.
DR HOGENOM; CLU_028225_0_1_1; -.
DR InParanoid; Q9LJ44; -.
DR OMA; PLAYKNI; -.
DR PhylomeDB; Q9LJ44; -.
DR PRO; PR:Q9LJ44; -.
DR Proteomes; UP000006548; Chromosome 3.
DR ExpressionAtlas; Q9LJ44; baseline and differential.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0010629; P:negative regulation of gene expression; IMP:TAIR.
DR GO; GO:0048579; P:negative regulation of long-day photoperiodism, flowering; IMP:TAIR.
DR GO; GO:2000032; P:regulation of secondary shoot formation; IMP:TAIR.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR010402; CCT_domain.
DR InterPro; IPR000315; Znf_B-box.
DR Pfam; PF06203; CCT; 1.
DR SMART; SM00336; BBOX; 1.
DR PROSITE; PS51017; CCT; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
PE 1: Evidence at protein level;
KW Metal-binding; Nucleus; Reference proteome; Repeat; Zinc; Zinc-finger.
FT CHAIN 1..364
FT /note="Zinc finger protein CONSTANS-LIKE 12"
FT /id="PRO_0000113289"
FT DOMAIN 280..322
FT /note="CCT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00357"
FT ZN_FING 5..47
FT /note="B box-type 1; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT ZN_FING 48..88
FT /note="B box-type 2; degenerate"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 5
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 8
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 28
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 33
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
SQ SEQUENCE 364 AA; 40470 MW; 51DB4F3917271171 CRC64;
MEPKCDHCAT SQALIYCKSD LAKLCLNCDV HVHSANPLSH RHIRSLICEK CFSQPAAIRC
LDEKVSYCQG CHWHESNCSE LGHRVQSLNP FSGCPSPTDF NRMWSSILEP PVSGLLSPFV
GSFPLNDLNN TMFDTAYSMV PHNISYTQNF SDNLSFFSTE SKGYPDMVLK LEEGEEDLCE
GLNLDDAPLN FDVGDDIIGC SSEVHIEPDH TVPNCLLIDK TNTSSFTGSN FTVDKALEAS
PPGQQMNINT GLQLPLSPVL FGQIHPSLNI TGENNAADYQ DCGMSPGFIM SEAPWETNFE
VSCPQARNEA KLRYKEKKLK RSFGKQIRYA SRKARADTRK RVKGRFVKAG DSYDYDPSSP
TTNN
