COL14_ARATH
ID COL14_ARATH Reviewed; 402 AA.
AC O22800; Q8H0T2; Q8L7Q6;
DT 05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2004, sequence version 2.
DT 03-AUG-2022, entry version 142.
DE RecName: Full=Zinc finger protein CONSTANS-LIKE 14;
GN Name=COL14; OrderedLocusNames=At2g33500; ORFNames=F4P9.27;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA] (ISOFORMS 1 AND 2).
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12692345; DOI=10.1104/pp.102.016188;
RA Griffiths S., Dunford R.P., Coupland G., Laurie D.A.;
RT "The evolution of CONSTANS-like gene families in barley, rice, and
RT Arabidopsis.";
RL Plant Physiol. 131:1855-1867(2003).
CC -!- INTERACTION:
CC O22800-2; Q9SJU5: BBX18; NbExp=3; IntAct=EBI-15192033, EBI-15192077;
CC O22800-2; C0SVM5: BBX19; NbExp=3; IntAct=EBI-15192033, EBI-4430993;
CC O22800-2; Q6NLH4: BBX29; NbExp=4; IntAct=EBI-15192033, EBI-15192709;
CC O22800-2; Q8L999-2: BPC6; NbExp=4; IntAct=EBI-15192033, EBI-15196639;
CC O22800-2; Q4PSE2: NFYC8; NbExp=3; IntAct=EBI-15192033, EBI-15191571;
CC O22800-2; Q8L4B2: NFYC9; NbExp=3; IntAct=EBI-15192033, EBI-2466050;
CC O22800-2; Q9LXU1: PIM1; NbExp=3; IntAct=EBI-15192033, EBI-15193025;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00357}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=2;
CC Name=1;
CC IsoId=O22800-1; Sequence=Displayed;
CC Name=2;
CC IsoId=O22800-2; Sequence=VSP_041588;
CC -!- SIMILARITY: Belongs to the CONSTANS family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAB80667.1; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
CC Sequence=AAM91524.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
CC Sequence=AAP21380.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC002332; AAB80667.1; ALT_SEQ; Genomic_DNA.
DR EMBL; CP002685; AEC08843.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC08844.1; -; Genomic_DNA.
DR EMBL; BT002067; AAN72078.1; -; mRNA.
DR EMBL; AY128321; AAM91524.1; ALT_INIT; mRNA.
DR EMBL; BT006572; AAP21380.1; ALT_INIT; mRNA.
DR PIR; C84746; C84746.
DR RefSeq; NP_850211.1; NM_179880.2. [O22800-1]
DR RefSeq; NP_973589.1; NM_201860.2. [O22800-2]
DR AlphaFoldDB; O22800; -.
DR BioGRID; 3262; 17.
DR IntAct; O22800; 16.
DR STRING; 3702.AT2G33500.1; -.
DR iPTMnet; O22800; -.
DR PaxDb; O22800; -.
DR PRIDE; O22800; -.
DR ProteomicsDB; 241146; -. [O22800-1]
DR EnsemblPlants; AT2G33500.1; AT2G33500.1; AT2G33500. [O22800-1]
DR EnsemblPlants; AT2G33500.2; AT2G33500.2; AT2G33500. [O22800-2]
DR GeneID; 817915; -.
DR Gramene; AT2G33500.1; AT2G33500.1; AT2G33500. [O22800-1]
DR Gramene; AT2G33500.2; AT2G33500.2; AT2G33500. [O22800-2]
DR KEGG; ath:AT2G33500; -.
DR Araport; AT2G33500; -.
DR TAIR; locus:2051104; AT2G33500.
DR eggNOG; ENOG502QW4H; Eukaryota.
DR InParanoid; O22800; -.
DR OMA; NIGGTSC; -.
DR OrthoDB; 1066605at2759; -.
DR PhylomeDB; O22800; -.
DR PRO; PR:O22800; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; O22800; baseline and differential.
DR Genevisible; O22800; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR010402; CCT_domain.
DR InterPro; IPR000315; Znf_B-box.
DR Pfam; PF06203; CCT; 1.
DR SMART; SM00336; BBOX; 2.
DR PROSITE; PS51017; CCT; 1.
DR PROSITE; PS50119; ZF_BBOX; 2.
PE 1: Evidence at protein level;
KW Alternative splicing; Coiled coil; Metal-binding; Nucleus;
KW Reference proteome; Repeat; Zinc; Zinc-finger.
FT CHAIN 1..402
FT /note="Zinc finger protein CONSTANS-LIKE 14"
FT /id="PRO_0000113291"
FT DOMAIN 357..399
FT /note="CCT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00357"
FT ZN_FING 12..54
FT /note="B box-type 1; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT ZN_FING 55..97
FT /note="B box-type 2; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT REGION 287..322
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 345..372
FT /evidence="ECO:0000255"
FT BINDING 12
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 15
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 35
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 40
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 55
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 58
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 78
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 83
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT VAR_SEQ 289
FT /note="Missing (in isoform 2)"
FT /evidence="ECO:0000303|PubMed:14593172"
FT /id="VSP_041588"
SQ SEQUENCE 402 AA; 44520 MW; 285854DB3BA3B350 CRC64;
MGTSTTESVV ACEFCGERTA VLFCRADTAK LCLPCDQHVH SANLLSRKHV RSQICDNCSK
EPVSVRCFTD NLVLCQECDW DVHGSCSSSA THERSAVEGF SGCPSVLELA AVWGIDLKGK
KKEDDEDELT KNFGMGLDSW GSGSNIVQEL IVPYDVSCKK QSFSFGRSKQ VVFEQLELLK
RGFVEGEGEI MVPEGINGGG SISQPSPTTS FTSLLMSQSL CGNGMQWNAT NHSTGQNTQI
WDFNLGQSRN PDEPSPVETK GSTFTFNNVT HLKNDTRTTN MNAFKESYQQ EDSVHSTSTK
GQETSKSNNI PAAIHSHKSS NDSCGLHCTE HIAITSNRAT RLVAVTNADL EQMAQNRDNA
MQRYKEKKKT RRYDKTIRYE TRKARAETRL RVKGRFVKAT DP
