COL15_ARATH
ID COL15_ARATH Reviewed; 433 AA.
AC Q9C7E8;
DT 05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-2001, sequence version 1.
DT 03-AUG-2022, entry version 135.
DE RecName: Full=Zinc finger protein CONSTANS-LIKE 15;
GN Name=COL15; OrderedLocusNames=At1g28050; ORFNames=F13K9.15;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12692345; DOI=10.1104/pp.102.016188;
RA Griffiths S., Dunford R.P., Coupland G., Laurie D.A.;
RT "The evolution of CONSTANS-like gene families in barley, rice, and
RT Arabidopsis.";
RL Plant Physiol. 131:1855-1867(2003).
CC -!- INTERACTION:
CC Q9C7E8; Q6NLH4: BBX29; NbExp=3; IntAct=EBI-2465998, EBI-15192709;
CC Q9C7E8; Q9LJB7: BBX32; NbExp=3; IntAct=EBI-2465998, EBI-4425264;
CC Q9C7E8; Q4PSE2: NFYC8; NbExp=3; IntAct=EBI-2465998, EBI-15191571;
CC Q9C7E8; Q8L4B2: NFYC9; NbExp=3; IntAct=EBI-2465998, EBI-2466050;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00357}.
CC -!- SIMILARITY: Belongs to the CONSTANS family. {ECO:0000305}.
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DR EMBL; AC069471; AAG51489.1; -; Genomic_DNA.
DR EMBL; CP002684; AEE30906.1; -; Genomic_DNA.
DR EMBL; AY037206; AAK59791.1; -; mRNA.
DR EMBL; BT002681; AAO11597.1; -; mRNA.
DR PIR; B86406; B86406.
DR RefSeq; NP_174126.1; NM_102570.4.
DR AlphaFoldDB; Q9C7E8; -.
DR SMR; Q9C7E8; -.
DR BioGRID; 24933; 17.
DR IntAct; Q9C7E8; 20.
DR STRING; 3702.AT1G28050.1; -.
DR PaxDb; Q9C7E8; -.
DR PRIDE; Q9C7E8; -.
DR ProteomicsDB; 241099; -.
DR EnsemblPlants; AT1G28050.1; AT1G28050.1; AT1G28050.
DR GeneID; 839698; -.
DR Gramene; AT1G28050.1; AT1G28050.1; AT1G28050.
DR KEGG; ath:AT1G28050; -.
DR Araport; AT1G28050; -.
DR TAIR; locus:2010504; AT1G28050.
DR eggNOG; ENOG502QW4H; Eukaryota.
DR HOGENOM; CLU_028225_0_0_1; -.
DR InParanoid; Q9C7E8; -.
DR OMA; WMSKDAP; -.
DR OrthoDB; 1066605at2759; -.
DR PhylomeDB; Q9C7E8; -.
DR PRO; PR:Q9C7E8; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9C7E8; baseline and differential.
DR Genevisible; Q9C7E8; AT.
DR GO; GO:0005634; C:nucleus; IEA:UniProtKB-SubCell.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; TAS:TAIR.
DR InterPro; IPR010402; CCT_domain.
DR InterPro; IPR000315; Znf_B-box.
DR Pfam; PF06203; CCT; 1.
DR SMART; SM00336; BBOX; 2.
DR PROSITE; PS51017; CCT; 1.
DR PROSITE; PS50119; ZF_BBOX; 2.
PE 1: Evidence at protein level;
KW Coiled coil; Metal-binding; Nucleus; Reference proteome; Repeat; Zinc;
KW Zinc-finger.
FT CHAIN 1..433
FT /note="Zinc finger protein CONSTANS-LIKE 15"
FT /id="PRO_0000113292"
FT DOMAIN 385..427
FT /note="CCT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00357"
FT ZN_FING 9..51
FT /note="B box-type 1; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT ZN_FING 52..94
FT /note="B box-type 2; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT REGION 319..353
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 374..398
FT /evidence="ECO:0000255"
FT COMPBIAS 325..353
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 9
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 12
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 32
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 37
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 52
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 55
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 75
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 80
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
SQ SEQUENCE 433 AA; 47606 MW; 69BD074D994D996B CRC64;
MSSSERVPCD FCGERTAVLF CRADTAKLCL PCDQQVHTAN LLSRKHVRSQ ICDNCGNEPV
SVRCFTDNLI LCQECDWDVH GSCSVSDAHV RSAVEGFSGC PSALELAALW GLDLEQGRKD
EENQVPMMAM MMDNFGMQLD SWVLGSNELI VPSDTTFKKR GSCGSSCGRY KQVLCKQLEE
LLKSGVVGGD GDDGDRDRDC DREGACDGDG DGEAGEGLMV PEMSERLKWS RDVEEINGGG
GGGVNQQWNA TTTNPSGGQS SQIWDFNLGQ SRGPEDTSRV EAAYVGKGAA SSFTINNFVD
HMNETCSTNV KGVKEIKKDD YKRSTSGQVQ PTKSESNNRP ITFGSEKGSN SSSDLHFTEH
IAGTSCKTTR LVATKADLER LAQNRGDAMQ RYKEKRKTRR YDKTIRYESR KARADTRLRV
RGRFVKASEA PYP
