COL16_ARATH
ID COL16_ARATH Reviewed; 417 AA.
AC Q8RWD0; Q9C6L4;
DT 27-SEP-2004, integrated into UniProtKB/Swiss-Prot.
DT 27-SEP-2004, sequence version 2.
DT 03-AUG-2022, entry version 113.
DE RecName: Full=Zinc finger protein CONSTANS-LIKE 16;
GN Name=COL16; OrderedLocusNames=At1g25440; ORFNames=F2J7.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12692345; DOI=10.1104/pp.102.016188;
RA Griffiths S., Dunford R.P., Coupland G., Laurie D.A.;
RT "The evolution of CONSTANS-like gene families in barley, rice, and
RT Arabidopsis.";
RL Plant Physiol. 131:1855-1867(2003).
CC -!- INTERACTION:
CC Q8RWD0; Q4PSE2: NFYC8; NbExp=3; IntAct=EBI-15192471, EBI-15191571;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00357}.
CC -!- SIMILARITY: Belongs to the CONSTANS family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAG50803.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR EMBL; AC079281; AAG50803.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE30625.1; -; Genomic_DNA.
DR EMBL; AY093174; AAM13173.1; -; mRNA.
DR PIR; E86384; E86384.
DR RefSeq; NP_173915.2; NM_102355.5.
DR AlphaFoldDB; Q8RWD0; -.
DR SMR; Q8RWD0; -.
DR BioGRID; 24367; 5.
DR IntAct; Q8RWD0; 5.
DR STRING; 3702.AT1G25440.1; -.
DR PaxDb; Q8RWD0; -.
DR PRIDE; Q8RWD0; -.
DR EnsemblPlants; AT1G25440.1; AT1G25440.1; AT1G25440.
DR GeneID; 839130; -.
DR Gramene; AT1G25440.1; AT1G25440.1; AT1G25440.
DR KEGG; ath:AT1G25440; -.
DR Araport; AT1G25440; -.
DR TAIR; locus:2031180; AT1G25440.
DR eggNOG; KOG1601; Eukaryota.
DR HOGENOM; CLU_035373_0_0_1; -.
DR InParanoid; Q8RWD0; -.
DR OMA; LLYCVPT; -.
DR OrthoDB; 689469at2759; -.
DR PhylomeDB; Q8RWD0; -.
DR PRO; PR:Q8RWD0; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q8RWD0; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR010402; CCT_domain.
DR InterPro; IPR000315; Znf_B-box.
DR Pfam; PF06203; CCT; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00336; BBOX; 1.
DR PROSITE; PS51017; CCT; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
PE 1: Evidence at protein level;
KW Coiled coil; Metal-binding; Nucleus; Reference proteome; Zinc; Zinc-finger.
FT CHAIN 1..417
FT /note="Zinc finger protein CONSTANS-LIKE 16"
FT /id="PRO_0000113293"
FT DOMAIN 361..403
FT /note="CCT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00357"
FT ZN_FING 17..59
FT /note="B box-type; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT REGION 63..105
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COILED 212..239
FT /evidence="ECO:0000255"
FT BINDING 17
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 20
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 40
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 45
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT CONFLICT 140
FT /note="V -> L (in Ref. 3; AAM13173)"
FT /evidence="ECO:0000305"
FT CONFLICT 211
FT /note="G -> E (in Ref. 3; AAM13173)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 417 AA; 46932 MW; B29F7E05040FEACB CRC64;
MMKSLANAVG AKTARACDSC VKRRARWYCA ADDAFLCQSC DSLVHSANPL ARRHERVRLK
TASPAVVKHS NHSSASPPHE VATWHHGFTR KARTPRGSGK KNNSSIFHDL VPDISIEDQT
DNYELEEQLI CQVPVLDPLV SEQFLNDVVE PKIEFPMIRS GLMIEEEEDN AESCLNGFFP
TDMELEEFAA DVETLLGRGL DTESYAMEEL GLSNSEMFKI EKDEIEEEVE EIKAMSMDIF
DDDRKDVDGT VPFELSFDYE SSHKTSEEEV MKNVESSGEC VVKVKEEEHK NVLMLRLNYD
SVISTWGGQG PPWSSGEPPE RDMDISGWPA FSMVENGGES THQKQYVGGC LPSSGFGDGG
REARVSRYRE KRRTRLFSKK IRYEVRKLNA EKRPRMKGRF VKRASLAAAA SPLGVNY
