COL1_ARATH
ID COL1_ARATH Reviewed; 355 AA.
AC O50055;
DT 05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-JUN-1998, sequence version 1.
DT 03-AUG-2022, entry version 158.
DE RecName: Full=Zinc finger protein CONSTANS-LIKE 1;
GN Name=COL1; OrderedLocusNames=At5g15850; ORFNames=F14F8_230;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [MRNA].
RC STRAIN=cv. Landsberg erecta; TISSUE=Aerial part;
RA Putterill J.J., Ledger S.E., Lee K., Robson F., Murphy G., Coupland G.;
RT "The flowering-time gene CONSTANS and homologue CONSTANS LIKE 1 exist as a
RT tandem repeat on chromosome 5 of Arabidopsis.";
RL (er) Plant Gene Register PGR97-077(1997).
RN [2]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130714; DOI=10.1038/35048507;
RA Tabata S., Kaneko T., Nakamura Y., Kotani H., Kato T., Asamizu E.,
RA Miyajima N., Sasamoto S., Kimura T., Hosouchi T., Kawashima K., Kohara M.,
RA Matsumoto M., Matsuno A., Muraki A., Nakayama S., Nakazaki N., Naruo K.,
RA Okumura S., Shinpo S., Takeuchi C., Wada T., Watanabe A., Yamada M.,
RA Yasuda M., Sato S., de la Bastide M., Huang E., Spiegel L., Gnoj L.,
RA O'Shaughnessy A., Preston R., Habermann K., Murray J., Johnson D.,
RA Rohlfing T., Nelson J., Stoneking T., Pepin K., Spieth J., Sekhon M.,
RA Armstrong J., Becker M., Belter E., Cordum H., Cordes M., Courtney L.,
RA Courtney W., Dante M., Du H., Edwards J., Fryman J., Haakensen B.,
RA Lamar E., Latreille P., Leonard S., Meyer R., Mulvaney E., Ozersky P.,
RA Riley A., Strowmatt C., Wagner-McPherson C., Wollam A., Yoakum M., Bell M.,
RA Dedhia N., Parnell L., Shah R., Rodriguez M., Hoon See L., Vil D.,
RA Baker J., Kirchoff K., Toth K., King L., Bahret A., Miller B., Marra M.A.,
RA Martienssen R., McCombie W.R., Wilson R.K., Murphy G., Bancroft I.,
RA Volckaert G., Wambutt R., Duesterhoeft A., Stiekema W., Pohl T.,
RA Entian K.-D., Terryn N., Hartley N., Bent E., Johnson S., Langham S.-A.,
RA McCullagh B., Robben J., Grymonprez B., Zimmermann W., Ramsperger U.,
RA Wedler H., Balke K., Wedler E., Peters S., van Staveren M., Dirkse W.,
RA Mooijman P., Klein Lankhorst R., Weitzenegger T., Bothe G., Rose M.,
RA Hauf J., Berneiser S., Hempel S., Feldpausch M., Lamberth S.,
RA Villarroel R., Gielen J., Ardiles W., Bents O., Lemcke K., Kolesov G.,
RA Mayer K.F.X., Rudd S., Schoof H., Schueller C., Zaccaria P., Mewes H.-W.,
RA Bevan M., Fransz P.F.;
RT "Sequence and analysis of chromosome 5 of the plant Arabidopsis thaliana.";
RL Nature 408:823-826(2000).
RN [3]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [5]
RP CHARACTERIZATION.
RC STRAIN=cv. C24;
RX PubMed=11359606; DOI=10.1046/j.1365-313x.2001.01003.x;
RA Ledger S.E., Strayer C., Ashton F., Kay S.A., Putterill J.J.;
RT "Analysis of the function of two circadian-regulated CONSTANS-LIKE genes.";
RL Plant J. 26:15-22(2001).
RN [6]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12692345; DOI=10.1104/pp.102.016188;
RA Griffiths S., Dunford R.P., Coupland G., Laurie D.A.;
RT "The evolution of CONSTANS-like gene families in barley, rice, and
RT Arabidopsis.";
RL Plant Physiol. 131:1855-1867(2003).
CC -!- FUNCTION: Putative transcription factor that may be involved in the
CC light input to the circadian clock but does not affect flowering time.
CC -!- INTERACTION:
CC O50055; C0SVM5: BBX19; NbExp=3; IntAct=EBI-1112154, EBI-4430993;
CC O50055; O82617: BBX23; NbExp=3; IntAct=EBI-1112154, EBI-15191793;
CC O50055; O50055: COL1; NbExp=2; IntAct=EBI-1112154, EBI-1112154;
CC O50055; Q8L4B2: NFYC9; NbExp=3; IntAct=EBI-1112154, EBI-2466050;
CC O50055; Q9SYX2: SPA1; NbExp=10; IntAct=EBI-1112154, EBI-626992;
CC O50055; Q9LJR3: SPA3; NbExp=7; IntAct=EBI-1112154, EBI-626921;
CC O50055; Q94BM7: SPA4; NbExp=7; IntAct=EBI-1112154, EBI-626943;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000305}.
CC -!- TISSUE SPECIFICITY: Highly expressed in leaves and at lower levels in
CC stems, flowers and siliques. Not detected in roots.
CC -!- DEVELOPMENTAL STAGE: Expressed throughout development.
CC -!- INDUCTION: Expressed with a circadian rhythm showing a peak at dawn.
CC -!- SIMILARITY: Belongs to the CONSTANS family. {ECO:0000305}.
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DR EMBL; Y10555; CAA71587.1; -; mRNA.
DR EMBL; Y10556; CAA71588.1; -; Genomic_DNA.
DR EMBL; AL391144; CAC01784.1; -; Genomic_DNA.
DR EMBL; CP002688; AED92215.1; -; Genomic_DNA.
DR EMBL; AY074369; AAL67065.1; -; mRNA.
DR EMBL; BT002363; AAN86196.1; -; mRNA.
DR PIR; T51414; T51414.
DR RefSeq; NP_197089.1; NM_121590.2.
DR AlphaFoldDB; O50055; -.
DR SMR; O50055; -.
DR BioGRID; 16718; 53.
DR IntAct; O50055; 47.
DR STRING; 3702.AT5G15850.1; -.
DR PaxDb; O50055; -.
DR PRIDE; O50055; -.
DR ProteomicsDB; 240918; -.
DR EnsemblPlants; AT5G15850.1; AT5G15850.1; AT5G15850.
DR GeneID; 831442; -.
DR Gramene; AT5G15850.1; AT5G15850.1; AT5G15850.
DR KEGG; ath:AT5G15850; -.
DR Araport; AT5G15850; -.
DR TAIR; locus:2143221; AT5G15850.
DR eggNOG; KOG1601; Eukaryota.
DR HOGENOM; CLU_028225_3_2_1; -.
DR InParanoid; O50055; -.
DR OMA; KQESNWA; -.
DR OrthoDB; 1303650at2759; -.
DR PhylomeDB; O50055; -.
DR PRO; PR:O50055; -.
DR Proteomes; UP000006548; Chromosome 5.
DR ExpressionAtlas; O50055; differential.
DR Genevisible; O50055; AT.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0042802; F:identical protein binding; IPI:IntAct.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0009909; P:regulation of flower development; IMP:TAIR.
DR InterPro; IPR010402; CCT_domain.
DR InterPro; IPR045281; CONSTANS-like.
DR InterPro; IPR000315; Znf_B-box.
DR PANTHER; PTHR31319; PTHR31319; 1.
DR Pfam; PF06203; CCT; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00336; BBOX; 2.
DR PROSITE; PS51017; CCT; 1.
DR PROSITE; PS50119; ZF_BBOX; 2.
PE 1: Evidence at protein level;
KW DNA-binding; Metal-binding; Nucleus; Reference proteome; Repeat;
KW Transcription; Transcription regulation; Zinc; Zinc-finger.
FT CHAIN 1..355
FT /note="Zinc finger protein CONSTANS-LIKE 1"
FT /id="PRO_0000113278"
FT DOMAIN 286..328
FT /note="CCT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00357"
FT ZN_FING 12..54
FT /note="B box-type 1; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT ZN_FING 55..97
FT /note="B box-type 2; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT REGION 252..281
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 252..268
FT /note="Polar residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 12
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 15
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 35
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 40
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 55
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 58
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 78
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 83
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
SQ SEQUENCE 355 AA; 39491 MW; 412C237A9CD30309 CRC64;
MLKVESNWAQ ACDTCRSAAC TVYCRADSAY LCSSCDAQVH AANRLASRHE RVRVCQSCER
APAAFFCKAD AASLCTTCDS EIHSANPLAR RHQRVPILPI SEYSYSSTAT NHSCETTVTD
PENRLVLGQE EEDEDEAEAA SWLLPNSGKN SGNNNGFSIG DEFLNLVDYS SSDKQFTDQS
NQYQLDCNVP QRSYGEDGVV PLQIEVSKGM YQEQQNFQLS INCGSWGALR SSNGSLSHMV
NVSSMDLGVV PESTTSDATV SNPRSPKAVT DQPPYPPAQM LSPRDREARV LRYREKKKMR
KFEKTIRYAS RKAYAEKRPR IKGRFAKKKD VDEEANQAFS TMITFDTGYG IVPSF
