COL3_ARATH
ID COL3_ARATH Reviewed; 294 AA.
AC Q9SK53; Q7G9K6; Q8LDY3;
DT 05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 01-MAY-2000, sequence version 1.
DT 03-AUG-2022, entry version 140.
DE RecName: Full=Zinc finger protein CONSTANS-LIKE 3;
GN Name=COL3; OrderedLocusNames=At2g24790; ORFNames=F27C12.29;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RA Brover V.V., Troukhan M.E., Alexandrov N.A., Lu Y.-P., Flavell R.B.,
RA Feldmann K.A.;
RT "Full-length cDNA from Arabidopsis thaliana.";
RL Submitted (MAR-2002) to the EMBL/GenBank/DDBJ databases.
RN [5]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12692345; DOI=10.1104/pp.102.016188;
RA Griffiths S., Dunford R.P., Coupland G., Laurie D.A.;
RT "The evolution of CONSTANS-like gene families in barley, rice, and
RT Arabidopsis.";
RL Plant Physiol. 131:1855-1867(2003).
CC -!- INTERACTION:
CC Q9SK53; P43254: COP1; NbExp=3; IntAct=EBI-1995108, EBI-301649;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00357}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9SK53-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the CONSTANS family. {ECO:0000305}.
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DR EMBL; AC006585; AAD23033.1; -; Genomic_DNA.
DR EMBL; AC007266; AAM15476.1; -; Genomic_DNA.
DR EMBL; CP002685; AEC07629.1; -; Genomic_DNA.
DR EMBL; AY058130; AAL25546.1; -; mRNA.
DR EMBL; AY140103; AAM98244.1; -; mRNA.
DR EMBL; BT002107; AAN72118.1; -; mRNA.
DR EMBL; AY085729; AAM62947.1; -; mRNA.
DR PIR; E84640; E84640.
DR RefSeq; NP_180052.1; NM_128038.3. [Q9SK53-1]
DR PDB; 6QTX; X-ray; 1.95 A; B=287-294.
DR PDBsum; 6QTX; -.
DR AlphaFoldDB; Q9SK53; -.
DR SMR; Q9SK53; -.
DR BioGRID; 2368; 14.
DR IntAct; Q9SK53; 11.
DR STRING; 3702.AT2G24790.1; -.
DR PaxDb; Q9SK53; -.
DR PRIDE; Q9SK53; -.
DR ProteomicsDB; 240920; -. [Q9SK53-1]
DR EnsemblPlants; AT2G24790.1; AT2G24790.1; AT2G24790. [Q9SK53-1]
DR GeneID; 817016; -.
DR Gramene; AT2G24790.1; AT2G24790.1; AT2G24790. [Q9SK53-1]
DR KEGG; ath:AT2G24790; -.
DR Araport; AT2G24790; -.
DR TAIR; locus:2047246; AT2G24790.
DR eggNOG; KOG1601; Eukaryota.
DR HOGENOM; CLU_028225_3_2_1; -.
DR InParanoid; Q9SK53; -.
DR OMA; ESECHET; -.
DR OrthoDB; 1303650at2759; -.
DR PhylomeDB; Q9SK53; -.
DR PRO; PR:Q9SK53; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q9SK53; baseline and differential.
DR Genevisible; Q9SK53; AT.
DR GO; GO:0005634; C:nucleus; IDA:TAIR.
DR GO; GO:0003700; F:DNA-binding transcription factor activity; ISS:TAIR.
DR GO; GO:0043565; F:sequence-specific DNA binding; IPI:TAIR.
DR GO; GO:0000976; F:transcription cis-regulatory region binding; IPI:TAIR.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0010161; P:red light signaling pathway; IMP:TAIR.
DR GO; GO:0009909; P:regulation of flower development; IBA:GO_Central.
DR GO; GO:0010099; P:regulation of photomorphogenesis; IMP:TAIR.
DR InterPro; IPR010402; CCT_domain.
DR InterPro; IPR045281; CONSTANS-like.
DR InterPro; IPR000315; Znf_B-box.
DR PANTHER; PTHR31319; PTHR31319; 1.
DR Pfam; PF06203; CCT; 1.
DR Pfam; PF00643; zf-B_box; 2.
DR SMART; SM00336; BBOX; 2.
DR PROSITE; PS51017; CCT; 1.
DR PROSITE; PS50119; ZF_BBOX; 2.
PE 1: Evidence at protein level;
KW 3D-structure; Alternative splicing; Metal-binding; Nucleus;
KW Reference proteome; Repeat; Zinc; Zinc-finger.
FT CHAIN 1..294
FT /note="Zinc finger protein CONSTANS-LIKE 3"
FT /id="PRO_0000113280"
FT DOMAIN 229..271
FT /note="CCT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00357"
FT ZN_FING 8..50
FT /note="B box-type 1; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT ZN_FING 51..93
FT /note="B box-type 2; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 8
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 11
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 31
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 36
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="1"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 51
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 54
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 74
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 79
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /ligand_label="2"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT CONFLICT 30
FT /note="D -> N (in Ref. 4; AAM62947)"
FT /evidence="ECO:0000305"
FT CONFLICT 286
FT /note="G -> C (in Ref. 4; AAM62947)"
FT /evidence="ECO:0000305"
SQ SEQUENCE 294 AA; 32324 MW; C4D3E3C63A551BB3 CRC64;
MASSSRLCDS CKSTAATLFC RADAAFLCGD CDGKIHTANK LASRHERVWL CEVCEQAPAH
VTCKADAAAL CVTCDRDIHS ANPLSRRHER VPITPFYDAV GPAKSASSSV NFVDEDGGDV
TASWLLAKEG IEITNLFSDL DYPKIEVTSE ENSSGNDGVV PVQNKLFLNE DYFNFDLSAS
KISQQGFNFI NQTVSTRTID VPLVPESGGV TAEMTNTETP AVQLSPAERE ARVLRYREKR
KNRKFEKTIR YASRKAYAEM RPRIKGRFAK RTDSRENDGG DVGVYGGFGV VPSF
