COL8_ARATH
ID COL8_ARATH Reviewed; 319 AA.
AC Q9M9B3; B9DH35;
DT 05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT 31-MAY-2011, sequence version 2.
DT 03-AUG-2022, entry version 115.
DE RecName: Full=Zinc finger protein CONSTANS-LIKE 8;
GN Name=COL8; OrderedLocusNames=At1g49130; ORFNames=F27J15.10;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=11130712; DOI=10.1038/35048500;
RA Theologis A., Ecker J.R., Palm C.J., Federspiel N.A., Kaul S., White O.,
RA Alonso J., Altafi H., Araujo R., Bowman C.L., Brooks S.Y., Buehler E.,
RA Chan A., Chao Q., Chen H., Cheuk R.F., Chin C.W., Chung M.K., Conn L.,
RA Conway A.B., Conway A.R., Creasy T.H., Dewar K., Dunn P., Etgu P.,
RA Feldblyum T.V., Feng J.-D., Fong B., Fujii C.Y., Gill J.E., Goldsmith A.D.,
RA Haas B., Hansen N.F., Hughes B., Huizar L., Hunter J.L., Jenkins J.,
RA Johnson-Hopson C., Khan S., Khaykin E., Kim C.J., Koo H.L.,
RA Kremenetskaia I., Kurtz D.B., Kwan A., Lam B., Langin-Hooper S., Lee A.,
RA Lee J.M., Lenz C.A., Li J.H., Li Y.-P., Lin X., Liu S.X., Liu Z.A.,
RA Luros J.S., Maiti R., Marziali A., Militscher J., Miranda M., Nguyen M.,
RA Nierman W.C., Osborne B.I., Pai G., Peterson J., Pham P.K., Rizzo M.,
RA Rooney T., Rowley D., Sakano H., Salzberg S.L., Schwartz J.R., Shinn P.,
RA Southwick A.M., Sun H., Tallon L.J., Tambunga G., Toriumi M.J., Town C.D.,
RA Utterback T., Van Aken S., Vaysberg M., Vysotskaia V.S., Walker M., Wu D.,
RA Yu G., Fraser C.M., Venter J.C., Davis R.W.;
RT "Sequence and analysis of chromosome 1 of the plant Arabidopsis thaliana.";
RL Nature 408:816-820(2000).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=19423640; DOI=10.1093/dnares/dsp009;
RA Iida K., Fukami-Kobayashi K., Toyoda A., Sakaki Y., Kobayashi M., Seki M.,
RA Shinozaki K.;
RT "Analysis of multiple occurrences of alternative splicing events in
RT Arabidopsis thaliana using novel sequenced full-length cDNAs.";
RL DNA Res. 16:155-164(2009).
RN [4]
RP GENE FAMILY, AND NOMENCLATURE.
RX PubMed=12692345; DOI=10.1104/pp.102.016188;
RA Griffiths S., Dunford R.P., Coupland G., Laurie D.A.;
RT "The evolution of CONSTANS-like gene families in barley, rice, and
RT Arabidopsis.";
RL Plant Physiol. 131:1855-1867(2003).
CC -!- INTERACTION:
CC Q9M9B3; Q4PSE2: NFYC8; NbExp=3; IntAct=EBI-15192397, EBI-15191571;
CC -!- SUBCELLULAR LOCATION: Nucleus {ECO:0000255|PROSITE-ProRule:PRU00357}.
CC -!- ALTERNATIVE PRODUCTS:
CC Event=Alternative splicing; Named isoforms=1;
CC Comment=A number of isoforms are produced. According to EST
CC sequences.;
CC Name=1;
CC IsoId=Q9M9B3-1; Sequence=Displayed;
CC -!- SIMILARITY: Belongs to the CONSTANS family. {ECO:0000305}.
CC -!- SEQUENCE CAUTION:
CC Sequence=AAF69700.1; Type=Erroneous initiation; Note=Truncated N-terminus.; Evidence={ECO:0000305};
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DR EMBL; AC016041; AAF69700.1; ALT_INIT; Genomic_DNA.
DR EMBL; CP002684; AEE32394.1; -; Genomic_DNA.
DR EMBL; AK317381; BAH20052.1; -; mRNA.
DR PIR; C96528; C96528.
DR RefSeq; NP_001031160.1; NM_001036083.2. [Q9M9B3-1]
DR AlphaFoldDB; Q9M9B3; -.
DR SMR; Q9M9B3; -.
DR BioGRID; 26561; 6.
DR IntAct; Q9M9B3; 6.
DR STRING; 3702.AT1G49130.1; -.
DR PaxDb; Q9M9B3; -.
DR PRIDE; Q9M9B3; -.
DR ProteomicsDB; 241101; -. [Q9M9B3-1]
DR EnsemblPlants; AT1G49130.2; AT1G49130.2; AT1G49130. [Q9M9B3-1]
DR GeneID; 841336; -.
DR Gramene; AT1G49130.2; AT1G49130.2; AT1G49130. [Q9M9B3-1]
DR KEGG; ath:AT1G49130; -.
DR Araport; AT1G49130; -.
DR eggNOG; KOG1601; Eukaryota.
DR HOGENOM; CLU_035373_0_0_1; -.
DR InParanoid; Q9M9B3; -.
DR PRO; PR:Q9M9B3; -.
DR Proteomes; UP000006548; Chromosome 1.
DR ExpressionAtlas; Q9M9B3; baseline and differential.
DR GO; GO:0005634; C:nucleus; IBA:GO_Central.
DR GO; GO:0008270; F:zinc ion binding; IEA:InterPro.
DR GO; GO:0006355; P:regulation of transcription, DNA-templated; IBA:GO_Central.
DR InterPro; IPR010402; CCT_domain.
DR InterPro; IPR000315; Znf_B-box.
DR Pfam; PF06203; CCT; 1.
DR Pfam; PF00643; zf-B_box; 1.
DR SMART; SM00336; BBOX; 1.
DR PROSITE; PS51017; CCT; 1.
DR PROSITE; PS50119; ZF_BBOX; 1.
PE 1: Evidence at protein level;
KW Alternative splicing; Metal-binding; Nucleus; Reference proteome; Zinc;
KW Zinc-finger.
FT CHAIN 1..319
FT /note="Zinc finger protein CONSTANS-LIKE 8"
FT /id="PRO_0000113285"
FT DOMAIN 271..313
FT /note="CCT"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00357"
FT ZN_FING 21..63
FT /note="B box-type; atypical"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT REGION 90..115
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT COMPBIAS 96..115
FT /note="Basic and acidic residues"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
FT BINDING 21
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 24
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 44
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
FT BINDING 49
FT /ligand="Zn(2+)"
FT /ligand_id="ChEBI:CHEBI:29105"
FT /evidence="ECO:0000255|PROSITE-ProRule:PRU00024"
SQ SEQUENCE 319 AA; 37501 MW; 39A6AEE249A64C48 CRC64;
MFCAEIMISK YQEDVKQPRA CELCLNKHAV WYCASDDAFL CHVCDESVHS ANHVATKHER
VCLRTNEISN DVRGGTTLTS VWHSGFRRKA RTPRSRYEKK PQQKIDDERR REDPRVPEIG
GEVMFFIPEA NDDDMTSLVP EFEGFTEMGF FLSNHNGTEE TTKQFNFEEE ADTMEDLYYN
GEEEDKTDGA EACPGQYLMS CKKDYDNVIT VSEKTEEIED CYENNARHRL NYENVIAAWD
KQESPRDVKN NTSSFQLVPP GIEEKRVRSE REARVWRYRD KRKNRLFEKK IRYEVRKVNA
DKRPRMKGRF VRRSLAIDS
