ID   COLI_CAMDR              Reviewed;          31 AA.
AC   P01203;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 53.
DE   RecName: Full=Beta-endorphin;
DE   Contains:
DE     RecName: Full=Met-enkephalin;
GN   Name=POMC;
OS   Camelus dromedarius (Dromedary) (Arabian camel).
OC   Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC   Eutheria; Laurasiatheria; Artiodactyla; Tylopoda; Camelidae; Camelus.
OX   NCBI_TaxID=9838;
RN   [1]
RP   PROTEIN SEQUENCE.
RX   PubMed=1063395; DOI=10.1073/pnas.73.4.1145;
RA   Li C.H., Chung D.;
RT   "Isolation and structure of an untriakontapeptide with opiate activity from
RT   camel pituitary glands.";
RL   Proc. Natl. Acad. Sci. U.S.A. 73:1145-1148(1976).
CC   -!- FUNCTION: Beta-endorphin and Met-enkephalin are endogenous opiates.
CC   -!- SUBCELLULAR LOCATION: Secreted.
CC   -!- SIMILARITY: Belongs to the POMC family. {ECO:0000305}.
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DR   PIR; A01468; OECMB.
DR   AlphaFoldDB; P01203; -.
DR   SMR; P01203; -.
DR   STRING; 9838.ENSCDRP00005014140; -.
DR   GO; GO:0005576; C:extracellular region; IEA:UniProtKB-SubCell.
DR   GO; GO:0007218; P:neuropeptide signaling pathway; IEA:UniProtKB-KW.
DR   InterPro; IPR013532; Opioid_neuropept.
DR   Pfam; PF08035; Op_neuropeptide; 1.
DR   SMART; SM01365; Op_neuropeptide; 1.
PE   1: Evidence at protein level;
KW   Direct protein sequencing; Endorphin; Secreted.
FT   PEPTIDE         1..31
FT                   /note="Beta-endorphin"
FT                   /id="PRO_0000045866"
FT   PEPTIDE         1..5
FT                   /note="Met-enkephalin"
FT                   /id="PRO_0000024954"
SQ   SEQUENCE   31 AA;  3438 MW;  93E140AF49144757 CRC64;
     YGGFMTSEKS QTPLVTLFKN AIIKNAHKKG Q