ID   COMA2_BACSU             Reviewed;         126 AA.
AC   P14205;
DT   01-JAN-1990, integrated into UniProtKB/Swiss-Prot.
DT   28-JUL-2009, sequence version 2.
DT   03-AUG-2022, entry version 120.
DE   RecName: Full=Putative esterase ComA2;
DE            EC=3.1.2.-;
DE   AltName: Full=ComA operon protein 2;
GN   Name=yuxO; Synonyms=comA2, comAB; OrderedLocusNames=BSU31670;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2507523; DOI=10.1128/jb.171.10.5362-5375.1989;
RA   Weinrauch Y., Guillen N., Dubnau D.;
RT   "Sequence and transcription mapping of Bacillus subtilis competence genes
RT   comB and comA, one of which is related to a family of bacterial regulatory
RT   determinants.";
RL   J. Bacteriol. 171:5362-5375(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9274030; DOI=10.1099/00221287-143-8-2769;
RA   Oudega B., Koningstein G., Rodrigues L., de Sales Ramon M., Hilbert H.,
RA   Duesterhoeft A., Pohl T.M., Weitzenegger T.;
RT   "Analysis of the Bacillus subtilis genome: cloning and nucleotide sequence
RT   of a 62 kb region between 275 degrees (rrnB) and 284 degrees (pai).";
RL   Microbiology 143:2769-2774(1997).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [4]
RP   SEQUENCE REVISION TO 54-55.
RX   PubMed=19383706; DOI=10.1099/mic.0.027839-0;
RA   Barbe V., Cruveiller S., Kunst F., Lenoble P., Meurice G., Sekowska A.,
RA   Vallenet D., Wang T., Moszer I., Medigue C., Danchin A.;
RT   "From a consortium sequence to a unified sequence: the Bacillus subtilis
RT   168 reference genome a decade later.";
RL   Microbiology 155:1758-1775(2009).
CC   -!- FUNCTION: Is not required for competence.
CC   -!- SIMILARITY: Belongs to the thioesterase PaaI family. {ECO:0000305}.
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DR   EMBL; M22856; AAA22321.1; -; Genomic_DNA.
DR   EMBL; Z93932; CAB07905.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15155.2; -; Genomic_DNA.
DR   PIR; B33591; B33591.
DR   RefSeq; NP_391045.2; NC_000964.3.
DR   RefSeq; WP_003228810.1; NZ_JNCM01000033.1.
DR   AlphaFoldDB; P14205; -.
DR   SMR; P14205; -.
DR   STRING; 224308.BSU31670; -.
DR   PaxDb; P14205; -.
DR   PRIDE; P14205; -.
DR   EnsemblBacteria; CAB15155; CAB15155; BSU_31670.
DR   GeneID; 937178; -.
DR   KEGG; bsu:BSU31670; -.
DR   PATRIC; fig|224308.179.peg.3432; -.
DR   eggNOG; COG2050; Bacteria.
DR   InParanoid; P14205; -.
DR   OMA; TTQVWQI; -.
DR   PhylomeDB; P14205; -.
DR   BioCyc; BSUB:BSU31670-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005829; C:cytosol; IBA:GO_Central.
DR   GO; GO:0061522; F:1,4-dihydroxy-2-naphthoyl-CoA thioesterase activity; IBA:GO_Central.
DR   InterPro; IPR029069; HotDog_dom_sf.
DR   InterPro; IPR003736; PAAI_dom.
DR   InterPro; IPR006683; Thioestr_dom.
DR   Pfam; PF03061; 4HBT; 1.
DR   SUPFAM; SSF54637; SSF54637; 1.
DR   TIGRFAMs; TIGR00369; unchar_dom_1; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Reference proteome.
FT   CHAIN           1..126
FT                   /note="Putative esterase ComA2"
FT                   /id="PRO_0000156679"
FT   CONFLICT        54..55
FT                   /note="SA -> RP (in Ref. 1; AAA22321 and 2; CAB07905)"
FT                   /evidence="ECO:0000305"
SQ   SEQUENCE   126 AA;  13681 MW;  C20A5F4180A4E733 CRC64;
     MDMKHTLLEA LGIEIVENTA ERCVAVMPVD HRTVQPFGYL HGGASVALAE TAASAGAQNL
     IDHTTQACVG LEINANHLKS VKEGTVKAIA EPVHIGRTTI VYHIHIYDEQ ERLICISRCT
     LAVIKK