ID   COMA_HAEIN              Reviewed;         265 AA.
AC   P31768;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   03-AUG-2022, entry version 79.
DE   RecName: Full=Competence protein A;
DE   AltName: Full=DNA transformation protein ComA;
GN   Name=comA; OrderedLocusNames=HI_0439;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=1916268; DOI=10.1016/0378-1119(91)90457-m;
RA   Tomb J.-F., El-Hajj H., Smith H.O.;
RT   "Nucleotide sequence of a cluster of genes involved in the transformation
RT   of Haemophilus influenzae Rd.";
RL   Gene 104:1-10(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Involved in transformation (competence for DNA uptake).
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DR   EMBL; M62809; AAA25008.1; -; Genomic_DNA.
DR   EMBL; L42023; AAC22098.1; -; Genomic_DNA.
DR   PIR; C64068; JH0430.
DR   RefSeq; NP_438600.1; NC_000907.1.
DR   RefSeq; WP_005693722.1; NC_000907.1.
DR   AlphaFoldDB; P31768; -.
DR   STRING; 71421.HI_0439; -.
DR   EnsemblBacteria; AAC22098; AAC22098; HI_0439.
DR   KEGG; hin:HI_0439; -.
DR   PATRIC; fig|71421.8.peg.459; -.
DR   eggNOG; COG4972; Bacteria.
DR   HOGENOM; CLU_091651_0_0_6; -.
DR   OMA; GYFDFVW; -.
DR   BioCyc; HINF71421:G1GJ1-454-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Competence; Reference proteome.
FT   CHAIN           1..265
FT                   /note="Competence protein A"
FT                   /id="PRO_0000090003"
SQ   SEQUENCE   265 AA;  31542 MW;  EC1E167D659A8759 CRC64;
     MQFSLKNYRT LQIGIHRKQS YFDFVWFDDL EQPQSYQIFV NDRYFKNRFL QQLKTQYQGK
     TFPLQFVASI PAHLTWSKVL MLPQVLNAQE CHQQCKFVIE KELPIFLEEL WFDYRSTPLK
     QGFRLEVTAI RKSSAQTYLQ DFQPFNINIL DVASNAVLRA FQYLLNEQVR SENTLFLFQE
     DDYCLAICER SQQSQILQSH ENLTALYEQF TERFEGQLEQ VFVYQIPSSH TPLPENWQRV
     ETELPFIALG NALWQKDLHQ QKVGG