ID   COMB_CALS4              Reviewed;         241 AA.
AC   Q8R8M3;
DT   02-AUG-2002, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2002, sequence version 1.
DT   25-MAY-2022, entry version 96.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490}; OrderedLocusNames=TTE1972;
OS   Caldanaerobacter subterraneus subsp. tengcongensis (strain DSM 15242 / JCM
OS   11007 / NBRC 100824 / MB4) (Thermoanaerobacter tengcongensis).
OC   Bacteria; Firmicutes; Clostridia; Thermoanaerobacterales;
OC   Thermoanaerobacteraceae; Caldanaerobacter.
OX   NCBI_TaxID=273068;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=DSM 15242 / JCM 11007 / NBRC 100824 / MB4;
RX   PubMed=11997336; DOI=10.1101/gr.219302;
RA   Bao Q., Tian Y., Li W., Xu Z., Xuan Z., Hu S., Dong W., Yang J., Chen Y.,
RA   Xue Y., Xu Y., Lai X., Huang L., Dong X., Ma Y., Ling L., Tan H., Chen R.,
RA   Wang J., Yu J., Yang H.;
RT   "A complete sequence of the T. tengcongensis genome.";
RL   Genome Res. 12:689-700(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
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DR   EMBL; AE008691; AAM25151.1; -; Genomic_DNA.
DR   RefSeq; WP_011026107.1; NC_003869.1.
DR   AlphaFoldDB; Q8R8M3; -.
DR   SMR; Q8R8M3; -.
DR   STRING; 273068.TTE1972; -.
DR   EnsemblBacteria; AAM25151; AAM25151; TTE1972.
DR   KEGG; tte:TTE1972; -.
DR   eggNOG; COG2045; Bacteria.
DR   HOGENOM; CLU_070028_0_0_9; -.
DR   OMA; RLFMSTT; -.
DR   OrthoDB; 1617556at2; -.
DR   Proteomes; UP000000555; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..241
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_0000081479"
SQ   SEQUENCE   241 AA;  27221 MW;  101C39E246E79969 CRC64;
     MFLQTYETYN SINDRDLKEK NVVVIDTLRA TSVITTALFN GAKEVIPVSE VEEAIELSKN
     FDRDTFLLAG ERNSQKIEGF DLSNSPLEYV PEKVKGKTII FTTTNGTRAL KKVASAEEVI
     LGCLLNVSAV ARYISKSNKD TVIVCAGTEG KFSFDDILTA GAIYEKLKSL TDFESDDLSK
     ASYFLYKPYE NNLYDIMKYG YHLRRLEELG YTEDIKFCLT VDKFDIVPKL KNGIVRTSQD
     F