ID   COMB_CLOK5              Reviewed;         240 AA.
AC   A5N4H7;
DT   20-MAY-2008, integrated into UniProtKB/Swiss-Prot.
DT   10-JUL-2007, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490}; OrderedLocusNames=CKL_0138;
OS   Clostridium kluyveri (strain ATCC 8527 / DSM 555 / NCIMB 10680).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=431943;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 8527 / DSM 555 / NCIMB 10680;
RX   PubMed=18218779; DOI=10.1073/pnas.0711093105;
RA   Seedorf H., Fricke W.F., Veith B., Brueggemann H., Liesegang H.,
RA   Strittmatter A., Miethke M., Buckel W., Hinderberger J., Li F.,
RA   Hagemeier C., Thauer R.K., Gottschalk G.;
RT   "The genome of Clostridium kluyveri, a strict anaerobe with unique
RT   metabolic features.";
RL   Proc. Natl. Acad. Sci. U.S.A. 105:2128-2133(2008).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
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DR   EMBL; CP000673; EDK32208.1; -; Genomic_DNA.
DR   RefSeq; WP_011988734.1; NC_009706.1.
DR   AlphaFoldDB; A5N4H7; -.
DR   SMR; A5N4H7; -.
DR   STRING; 431943.CKL_0138; -.
DR   EnsemblBacteria; EDK32208; EDK32208; CKL_0138.
DR   KEGG; ckl:CKL_0138; -.
DR   eggNOG; COG2045; Bacteria.
DR   HOGENOM; CLU_070028_0_0_9; -.
DR   OMA; RLFMSTT; -.
DR   OrthoDB; 1617556at2; -.
DR   Proteomes; UP000002411; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..240
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_1000081393"
SQ   SEQUENCE   240 AA;  27104 MW;  27B317B9BBA406FB CRC64;
     MKIDIIISAD DIKKEKILHK SVIVVDMLRA TSVIITAINN GCREVIPVLT IEEALEIYHK
     NREKYVMGGE RKALKIEGFH CSNSPLEYSR QVVENKTLVI TTSNGTKAIK GSIMAKNILI
     GALINADEVA NRSINLNNDV VIVNAGTCGQ FSIDDFICSG YMINCVIKKI KVDLTDIART
     ALYIYEQNPD IITFIKKASH YKRIKKLKLY DDLEYCCRKD IIKIVPEYID GIIKCNKLIY