ID   COMB_CLONN              Reviewed;         235 AA.
AC   A0Q380;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   09-JAN-2007, sequence version 1.
DT   25-MAY-2022, entry version 74.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490}; OrderedLocusNames=NT01CX_0616;
OS   Clostridium novyi (strain NT).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=386415;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NT;
RX   PubMed=17115055; DOI=10.1038/nbt1256;
RA   Bettegowda C., Huang X., Lin J., Cheong I., Kohli M., Szabo S.A., Zhang X.,
RA   Diaz L.A. Jr., Velculescu V.E., Parmigiani G., Kinzler K.W., Vogelstein B.,
RA   Zhou S.;
RT   "The genome and transcriptomes of the anti-tumor agent Clostridium novyi-
RT   NT.";
RL   Nat. Biotechnol. 24:1573-1580(2006).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
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DR   EMBL; CP000382; ABK60442.1; -; Genomic_DNA.
DR   RefSeq; WP_011723061.1; NC_008593.1.
DR   AlphaFoldDB; A0Q380; -.
DR   SMR; A0Q380; -.
DR   STRING; 386415.NT01CX_0616; -.
DR   EnsemblBacteria; ABK60442; ABK60442; NT01CX_0616.
DR   KEGG; cno:NT01CX_0616; -.
DR   PATRIC; fig|386415.7.peg.2119; -.
DR   eggNOG; COG2045; Bacteria.
DR   HOGENOM; CLU_070028_0_0_9; -.
DR   OMA; RLFMSTT; -.
DR   OrthoDB; 1617556at2; -.
DR   Proteomes; UP000008220; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..235
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_1000014462"
SQ   SEQUENCE   235 AA;  26135 MW;  AAB79203DB32262E CRC64;
     MKIDLIISAS DIKEEKIKNK TVVVIDILRA TSVIVTALNN GCNEVIPVLE VEDAMKIVKD
     NRKKYILGGE RNALKIEGFD FSNSPLDYTK DVVKDKTLVM TTTNGTRAIH GAMSAKNILI
     GAMINARSIA NKVLELDNDL IIINSGTNGE FSIDDFVCAG YIIDCILKNR DAELSDIAIT
     AHYVYSENKD IHSFVHKAKH YNILSNLGLK DDINYCCSKD IVDIVPEFHY PKITK