ID   COMB_CLOPE              Reviewed;         247 AA.
AC   Q8XHC9;
DT   27-MAR-2002, integrated into UniProtKB/Swiss-Prot.
DT   27-MAR-2002, sequence version 1.
DT   25-MAY-2022, entry version 105.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490}; OrderedLocusNames=CPE2556;
OS   Clostridium perfringens (strain 13 / Type A).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=195102;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=13 / Type A;
RX   PubMed=11792842; DOI=10.1073/pnas.022493799;
RA   Shimizu T., Ohtani K., Hirakawa H., Ohshima K., Yamashita A., Shiba T.,
RA   Ogasawara N., Hattori M., Kuhara S., Hayashi H.;
RT   "Complete genome sequence of Clostridium perfringens, an anaerobic flesh-
RT   eater.";
RL   Proc. Natl. Acad. Sci. U.S.A. 99:996-1001(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
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DR   EMBL; BA000016; BAB82262.1; -; Genomic_DNA.
DR   RefSeq; WP_011010963.1; NC_003366.1.
DR   AlphaFoldDB; Q8XHC9; -.
DR   SMR; Q8XHC9; -.
DR   STRING; 195102.gene:10491890; -.
DR   EnsemblBacteria; BAB82262; BAB82262; BAB82262.
DR   KEGG; cpe:CPE2556; -.
DR   HOGENOM; CLU_070028_0_0_9; -.
DR   OMA; RLFMSTT; -.
DR   Proteomes; UP000000818; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..247
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_0000081466"
SQ   SEQUENCE   247 AA;  27190 MW;  3820A2CF1B696082 CRC64;
     MKIDVIISAD YIDSESLKGK IAVVIDMLRA TSVITTALYN GAKKVIPVVS VEEAFEKANE
     LKSLGEEVLL GGERKALKID GFDFSNSPLE YKREIVEGKN VIMSTTNGTR ALNLCNKADK
     VIVASVLNGQ AVAKYLENEE KEIVFVNSGT NGEFSSDDFM CAGYIISEIC KNKEAELTDI
     AKTAKYVCES SEGIEEFIKD AKHYNILKNL GLEEDLKYCS TKNLIDLVFE FKNGEIKTVE
     SGVKVTI