ID   COMB_CLOTE              Reviewed;         233 AA.
AC   Q899J5;
DT   27-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   27-JUN-2003, sequence version 2.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490}; OrderedLocusNames=CTC_00180;
OS   Clostridium tetani (strain Massachusetts / E88).
OC   Bacteria; Firmicutes; Clostridia; Eubacteriales; Clostridiaceae;
OC   Clostridium.
OX   NCBI_TaxID=212717;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Massachusetts / E88;
RX   PubMed=12552129; DOI=10.1073/pnas.0335853100;
RA   Brueggemann H., Baeumer S., Fricke W.F., Wiezer A., Liesegang H.,
RA   Decker I., Herzberg C., Martinez-Arias R., Merkl R., Henne A.,
RA   Gottschalk G.;
RT   "The genome sequence of Clostridium tetani, the causative agent of tetanus
RT   disease.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:1316-1321(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAO34831.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; AE015927; AAO34831.1; ALT_INIT; Genomic_DNA.
DR   RefSeq; WP_035110650.1; NC_004557.1.
DR   AlphaFoldDB; Q899J5; -.
DR   SMR; Q899J5; -.
DR   STRING; 212717.CTC_00180; -.
DR   PRIDE; Q899J5; -.
DR   EnsemblBacteria; AAO34831; AAO34831; CTC_00180.
DR   GeneID; 64181050; -.
DR   KEGG; ctc:CTC_00180; -.
DR   HOGENOM; CLU_070028_0_0_9; -.
DR   OMA; RLFMSTT; -.
DR   OrthoDB; 1617556at2; -.
DR   Proteomes; UP000001412; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..233
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_0000081467"
SQ   SEQUENCE   233 AA;  25990 MW;  4E9D06D95CC57DCE CRC64;
     MNIDIIISAD DIKEEKIKDK SIVVIDILRA TSVIITALNN GCKEVVPVVE IEEALEKVKN
     NRKNYILGGE RKALKIEGFD CSNSPLEYKS ELVKGKTLVI TTSNGTRAIK EALLAKDILI
     GALINGKAVA EKLISLKNDV VIINAGTYGE FSIDDFICSG YIIDCIAKDM EVKLSDISKV
     AKYLYNMNTN MEFIKEAKHF KRIMELGLFM DLEYCCKKDI VSIVPQYKNG IIK