ID   COMB_PROM3              Reviewed;         243 AA.
AC   A2CAX3;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   20-FEB-2007, sequence version 1.
DT   03-AUG-2022, entry version 72.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490}; OrderedLocusNames=P9303_18911;
OS   Prochlorococcus marinus (strain MIT 9303).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=59922;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=MIT 9303;
RX   PubMed=18159947; DOI=10.1371/journal.pgen.0030231;
RA   Kettler G.C., Martiny A.C., Huang K., Zucker J., Coleman M.L., Rodrigue S.,
RA   Chen F., Lapidus A., Ferriera S., Johnson J., Steglich C., Church G.M.,
RA   Richardson P., Chisholm S.W.;
RT   "Patterns and implications of gene gain and loss in the evolution of
RT   Prochlorococcus.";
RL   PLoS Genet. 3:2515-2528(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
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DR   EMBL; CP000554; ABM78633.1; -; Genomic_DNA.
DR   AlphaFoldDB; A2CAX3; -.
DR   SMR; A2CAX3; -.
DR   EnsemblBacteria; ABM78633; ABM78633; P9303_18911.
DR   KEGG; pmf:P9303_18911; -.
DR   HOGENOM; CLU_070028_0_1_3; -.
DR   OMA; RLFMSTT; -.
DR   BioCyc; PMAR59922:G1G80-1640-MON; -.
DR   Proteomes; UP000002274; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium.
FT   CHAIN           1..243
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_1000014467"
SQ   SEQUENCE   243 AA;  26204 MW;  AC442CE48E71CDE3 CRC64;
     MQLAYFHVAA DVPQGAEPDA AVVIDVLRAT TTIAWALNNG AEAVETFADL DQLRQSAAQW
     PESSRLMLGE RGGQRIEGFD LGNSPVAVVP EQVAGKRLFM STTNGTRSLQ RVRGVQRLFT
     LALPNRRAVA DHLLMDPPEQ LWIVGSGWEG AYSLEDSLAA GALADLLLNA AADEACVVND
     ELTAALALWQ QWKHDPEACL RQASHGQRLI GLGDHDADFR CCAELDRLSV VPVQVKPGVL
     CAS