ID   COMB_PROMA              Reviewed;         243 AA.
AC   Q7VBP6;
DT   02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2003, sequence version 1.
DT   25-MAY-2022, entry version 91.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490}; OrderedLocusNames=Pro_1046;
OS   Prochlorococcus marinus (strain SARG / CCMP1375 / SS120).
OC   Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC   Prochlorococcus.
OX   NCBI_TaxID=167539;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=SARG / CCMP1375 / SS120;
RX   PubMed=12917486; DOI=10.1073/pnas.1733211100;
RA   Dufresne A., Salanoubat M., Partensky F., Artiguenave F., Axmann I.M.,
RA   Barbe V., Duprat S., Galperin M.Y., Koonin E.V., Le Gall F., Makarova K.S.,
RA   Ostrowski M., Oztas S., Robert C., Rogozin I.B., Scanlan D.J.,
RA   Tandeau de Marsac N., Weissenbach J., Wincker P., Wolf Y.I., Hess W.R.;
RT   "Genome sequence of the cyanobacterium Prochlorococcus marinus SS120, a
RT   nearly minimal oxyphototrophic genome.";
RL   Proc. Natl. Acad. Sci. U.S.A. 100:10020-10025(2003).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
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DR   EMBL; AE017126; AAQ00091.1; -; Genomic_DNA.
DR   RefSeq; NP_875438.1; NC_005042.1.
DR   RefSeq; WP_011125198.1; NC_005042.1.
DR   AlphaFoldDB; Q7VBP6; -.
DR   SMR; Q7VBP6; -.
DR   STRING; 167539.Pro_1046; -.
DR   EnsemblBacteria; AAQ00091; AAQ00091; Pro_1046.
DR   GeneID; 54200388; -.
DR   KEGG; pma:Pro_1046; -.
DR   PATRIC; fig|167539.5.peg.1096; -.
DR   eggNOG; COG2045; Bacteria.
DR   HOGENOM; CLU_070028_0_1_3; -.
DR   OMA; RLFMSTT; -.
DR   OrthoDB; 1617556at2; -.
DR   Proteomes; UP000001420; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..243
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_0000081470"
SQ   SEQUENCE   243 AA;  26435 MW;  E076FD54F38C7953 CRC64;
     MELSYFHVAK DVPSGIKPET SVVIDVLRAT TTIACALNNG AEAVQTFADL DNLKEQASCW
     PLSKRLLLGE RGGKKIDGFD LGNSPLAVTS NVVKGKRLFM STTNGTRSLE RVKESKSLYT
     MSFINRKAVA EKLISNQSKS VLILGSGWEG AYSLEDSLAA GALASFLLNK NPNSVHILND
     ELSAAVALWS CWENNIEGCL RNATHGKRLE RLGNHDDDFT CCSELDKICV VPTQREKGVL
     CSL