COMB_PROMM
ID COMB_PROMM Reviewed; 243 AA.
AC Q7V8F6;
DT 02-FEB-2004, integrated into UniProtKB/Swiss-Prot.
DT 01-OCT-2003, sequence version 1.
DT 25-MAY-2022, entry version 89.
DE RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN Name=comB {ECO:0000255|HAMAP-Rule:MF_00490}; OrderedLocusNames=PMT_0396;
OS Prochlorococcus marinus (strain MIT 9313).
OC Bacteria; Cyanobacteria; Synechococcales; Prochlorococcaceae;
OC Prochlorococcus.
OX NCBI_TaxID=74547;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=MIT 9313;
RX PubMed=12917642; DOI=10.1038/nature01947;
RA Rocap G., Larimer F.W., Lamerdin J.E., Malfatti S., Chain P., Ahlgren N.A.,
RA Arellano A., Coleman M., Hauser L., Hess W.R., Johnson Z.I., Land M.L.,
RA Lindell D., Post A.F., Regala W., Shah M., Shaw S.L., Steglich C.,
RA Sullivan M.B., Ting C.S., Tolonen A., Webb E.A., Zinser E.R.,
RA Chisholm S.W.;
RT "Genome divergence in two Prochlorococcus ecotypes reflects oceanic niche
RT differentiation.";
RL Nature 424:1042-1047(2003).
CC -!- CATALYTIC ACTIVITY:
CC Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC -!- COFACTOR:
CC Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC Rule:MF_00490}.
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DR EMBL; BX548175; CAE20571.1; -; Genomic_DNA.
DR RefSeq; WP_011129775.1; NC_005071.1.
DR AlphaFoldDB; Q7V8F6; -.
DR SMR; Q7V8F6; -.
DR STRING; 74547.PMT_0396; -.
DR EnsemblBacteria; CAE20571; CAE20571; PMT_0396.
DR KEGG; pmt:PMT_0396; -.
DR eggNOG; COG2045; Bacteria.
DR HOGENOM; CLU_070028_0_1_3; -.
DR OMA; RLFMSTT; -.
DR OrthoDB; 1617556at2; -.
DR Proteomes; UP000001423; Chromosome.
DR GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR Gene3D; 3.90.1560.10; -; 1.
DR HAMAP; MF_00490; ComB; 1.
DR InterPro; IPR005238; ComB-like.
DR InterPro; IPR036702; ComB-like_sf.
DR PANTHER; PTHR37311; PTHR37311; 1.
DR Pfam; PF04029; 2-ph_phosp; 1.
DR SUPFAM; SSF142823; SSF142823; 1.
PE 3: Inferred from homology;
KW Hydrolase; Magnesium; Reference proteome.
FT CHAIN 1..243
FT /note="Probable 2-phosphosulfolactate phosphatase"
FT /id="PRO_0000081471"
SQ SEQUENCE 243 AA; 26149 MW; 5C5B325E39F85C2C CRC64;
MQLAYFHVAA DVPQGAEPDA AVVIDVLRAT TTIAWALNNG AEAVETFADL DQLRQSAAQW
PESSRLMLGE RGGQRIEGFD LGNSPVAVVP EQVAGKRLFM STTNGTRSLQ RVRGVQRLFT
LALPNRKAVA DHLLMDPPEQ LWIVGSGWEG AYSLEDSLAA GALADLLLDA AADEACVAND
ELTAALALWQ QWKHDPEACL RQASHGQRLI GLGDHDADFR CCAELDRLSV VPVQVKPGVL
CAS