ID   COMB_SYNJB              Reviewed;         242 AA.
AC   Q2JPJ7;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   07-MAR-2006, sequence version 1.
DT   25-MAY-2022, entry version 84.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490}; OrderedLocusNames=CYB_0287;
OS   Synechococcus sp. (strain JA-2-3B'a(2-13)) (Cyanobacteria bacterium
OS   Yellowstone B-Prime).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=321332;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=JA-2-3B'a(2-13);
RX   PubMed=18059494; DOI=10.1038/ismej.2007.46;
RA   Bhaya D., Grossman A.R., Steunou A.-S., Khuri N., Cohan F.M., Hamamura N.,
RA   Melendrez M.C., Bateson M.M., Ward D.M., Heidelberg J.F.;
RT   "Population level functional diversity in a microbial community revealed by
RT   comparative genomic and metagenomic analyses.";
RL   ISME J. 1:703-713(2007).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
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DR   EMBL; CP000240; ABD01285.1; -; Genomic_DNA.
DR   RefSeq; WP_011431954.1; NC_007776.1.
DR   AlphaFoldDB; Q2JPJ7; -.
DR   SMR; Q2JPJ7; -.
DR   STRING; 321332.CYB_0287; -.
DR   KEGG; cyb:CYB_0287; -.
DR   eggNOG; COG2045; Bacteria.
DR   HOGENOM; CLU_070028_0_1_3; -.
DR   OMA; RLFMSTT; -.
DR   OrthoDB; 1617556at2; -.
DR   Proteomes; UP000001938; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..242
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_1000014470"
SQ   SEQUENCE   242 AA;  25942 MW;  AFA132E60C78F3B9 CRC64;
     MRFFHFYTPE QVPSSGIPEC AVAIDVLRAT TTIATALAAG AEAVQVFAHL QQLQEASQNW
     PASQRLLAGE RGGKAVAGFD LGNSPLDYTP DRVRDKRIFL STTNGTRSLQ RLEGIPVVIT
     AALVNLGAVV DFLRRGSFAE VWLVGSGWEG AFSLEDTACA GAILHRLGCS LNQLGNDETL
     AALALYQTWQ DDLLGLLRRS SHGQRLLGLG PENDQDLAYC ADLDRLSVVP RQVQPGVLAS
     GG