ID   COMB_SYNPW              Reviewed;         246 AA.
AC   A5GKJ5;
DT   15-JAN-2008, integrated into UniProtKB/Swiss-Prot.
DT   12-JUN-2007, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490};
GN   OrderedLocusNames=SynWH7803_1034;
OS   Synechococcus sp. (strain WH7803).
OC   Bacteria; Cyanobacteria; Synechococcales; Synechococcaceae; Synechococcus;
OC   unclassified Synechococcus.
OX   NCBI_TaxID=32051;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=WH7803;
RG   Genoscope;
RL   Submitted (MAY-2006) to the EMBL/GenBank/DDBJ databases.
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CT971583; CAK23460.1; -; Genomic_DNA.
DR   RefSeq; WP_011932942.1; NC_009481.1.
DR   AlphaFoldDB; A5GKJ5; -.
DR   SMR; A5GKJ5; -.
DR   STRING; 32051.SynWH7803_1034; -.
DR   EnsemblBacteria; CAK23460; CAK23460; SynWH7803_1034.
DR   KEGG; syx:SynWH7803_1034; -.
DR   eggNOG; COG2045; Bacteria.
DR   HOGENOM; CLU_070028_0_1_3; -.
DR   OMA; RLFMSTT; -.
DR   OrthoDB; 1617556at2; -.
DR   Proteomes; UP000001566; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..246
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_1000014471"
SQ   SEQUENCE   246 AA;  26525 MW;  BCE80C2870BA3CC9 CRC64;
     MQVSYFHVAA DVPDAIGSVE GPDAAVVIDV LRATTTIAWA LHNGAEAVQA FADLDELRLQ
     SRNWPEQTRL LLGERGGRML EGFDLGNSPV AVIPEVVQGK RLFMSTTNGT RALQRVRDVS
     VVMTVALPNR QAVAQRLLRD QPERVWMVGS GWEGTYSLED SLAAGALADA LVAAGAQVAN
     DELQAALALW AQWKHDPEAC LRVASHGQRL TRLGNHDADF SCCAGLDQLS VVPTQTEPGV
     LRAIRV