ID   COMB_SYNY3              Reviewed;         241 AA.
AC   P73849;
DT   05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1997, sequence version 1.
DT   25-MAY-2022, entry version 119.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase;
DE            EC=3.1.3.71;
GN   Name=comB; OrderedLocusNames=slr1718;
OS   Synechocystis sp. (strain PCC 6803 / Kazusa).
OC   Bacteria; Cyanobacteria; Synechococcales; Merismopediaceae; Synechocystis;
OC   unclassified Synechocystis.
OX   NCBI_TaxID=1111708;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=PCC 6803 / Kazusa;
RX   PubMed=8905231; DOI=10.1093/dnares/3.3.109;
RA   Kaneko T., Sato S., Kotani H., Tanaka A., Asamizu E., Nakamura Y.,
RA   Miyajima N., Hirosawa M., Sugiura M., Sasamoto S., Kimura T., Hosouchi T.,
RA   Matsuno A., Muraki A., Nakazaki N., Naruo K., Okumura S., Shimpo S.,
RA   Takeuchi C., Wada T., Watanabe A., Yamada M., Yasuda M., Tabata S.;
RT   "Sequence analysis of the genome of the unicellular cyanobacterium
RT   Synechocystis sp. strain PCC6803. II. Sequence determination of the entire
RT   genome and assignment of potential protein-coding regions.";
RL   DNA Res. 3:109-136(1996).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000305}.
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DR   EMBL; BA000022; BAA17908.1; -; Genomic_DNA.
DR   PIR; S75046; S75046.
DR   AlphaFoldDB; P73849; -.
DR   SMR; P73849; -.
DR   STRING; 1148.1652991; -.
DR   PaxDb; P73849; -.
DR   EnsemblBacteria; BAA17908; BAA17908; BAA17908.
DR   KEGG; syn:slr1718; -.
DR   eggNOG; COG2045; Bacteria.
DR   InParanoid; P73849; -.
DR   OMA; RLFMSTT; -.
DR   PhylomeDB; P73849; -.
DR   Proteomes; UP000001425; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   GO; GO:0050545; F:sulfopyruvate decarboxylase activity; IBA:GO_Central.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..241
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_0000081476"
SQ   SEQUENCE   241 AA;  26046 MW;  46D75910F3D53042 CRC64;
     MEIFVYHTPE LTPDQSLPDC AVVIDVLRAT TTIATALKVG AEAVQVFSSL DDLMATSESW
     PGEKRLRAGE RGGAAVAGYD LGNSPLDCTS ELMAGKRLFL STTNGTRALQ RVKDCPQLVT
     ASLVNRGAAV DYLAQTQPKT VWLLGSGWEG GYSLEDTVCA GAIASLLREK GIDFTVGNDE
     VVAAQSLYRQ WRSDLLNLFK QASHGQRLLK LDRLEDLRYC ATEDLIDILP KQVSPGVLTA
     A