ID   COMB_THEAC              Reviewed;         220 AA.
AC   Q9HIA9;
DT   05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2001, sequence version 1.
DT   25-MAY-2022, entry version 92.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase;
DE            EC=3.1.3.71;
GN   Name=comB; OrderedLocusNames=Ta1432;
OS   Thermoplasma acidophilum (strain ATCC 25905 / DSM 1728 / JCM 9062 / NBRC
OS   15155 / AMRC-C165).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273075;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 25905 / DSM 1728 / JCM 9062 / NBRC 15155 / AMRC-C165;
RX   PubMed=11029001; DOI=10.1038/35035069;
RA   Ruepp A., Graml W., Santos-Martinez M.-L., Koretke K.K., Volker C.,
RA   Mewes H.-W., Frishman D., Stocker S., Lupas A.N., Baumeister W.;
RT   "The genome sequence of the thermoacidophilic scavenger Thermoplasma
RT   acidophilum.";
RL   Nature 407:508-513(2000).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000305}.
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DR   EMBL; AL445067; CAC12552.1; -; Genomic_DNA.
DR   RefSeq; WP_010901835.1; NC_002578.1.
DR   AlphaFoldDB; Q9HIA9; -.
DR   SMR; Q9HIA9; -.
DR   EnsemblBacteria; CAC12552; CAC12552; CAC12552.
DR   GeneID; 1456888; -.
DR   KEGG; tac:Ta1432; -.
DR   eggNOG; arCOG04871; Archaea.
DR   HOGENOM; CLU_070028_0_0_2; -.
DR   OMA; CAQYIAR; -.
DR   OrthoDB; 84054at2157; -.
DR   Proteomes; UP000001024; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..220
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_0000081461"
SQ   SEQUENCE   220 AA;  24654 MW;  1F9643CC4BCA7428 CRC64;
     MIRIGDGRKS DSWAEINVVV DIFRSTTTIP MILFRGAKYI LPFRDVRKAI EFKRRNPGTI
     LVGEKYGIKP PYFDYDNSPA EIAEADLSGK VVAFTSTNGT YVLSRIRSGR IIFSSYVNLS
     ATVAMIRSQR DVLILPSNRP IGKAPEDILF ANLLKLMAEG HEVDVSEYTR KTEEINRNII
     AGVGERDLEF CLRVDHTNIV PEYIDGRIVQ SPDSVALTDA