ID   COMB_THEVB              Reviewed;         244 AA.
AC   Q8DLS5;
DT   27-JUN-2003, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-2003, sequence version 1.
DT   03-AUG-2022, entry version 95.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase {ECO:0000255|HAMAP-Rule:MF_00490};
DE            EC=3.1.3.71 {ECO:0000255|HAMAP-Rule:MF_00490};
GN   Name=comB {ECO:0000255|HAMAP-Rule:MF_00490}; OrderedLocusNames=tll0403;
OS   Thermosynechococcus vestitus (strain NIES-2133 / IAM M-273 / BP-1).
OC   Bacteria; Cyanobacteria; Pseudanabaenales; Thermosynechococcaceae;
OC   Thermosynechococcus.
OX   NCBI_TaxID=197221;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=NIES-2133 / IAM M-273 / BP-1;
RX   PubMed=12240834; DOI=10.1093/dnares/9.4.123;
RA   Nakamura Y., Kaneko T., Sato S., Ikeuchi M., Katoh H., Sasamoto S.,
RA   Watanabe A., Iriguchi M., Kawashima K., Kimura T., Kishida Y., Kiyokawa C.,
RA   Kohara M., Matsumoto M., Matsuno A., Nakazaki N., Shimpo S., Sugimoto M.,
RA   Takeuchi C., Yamada M., Tabata S.;
RT   "Complete genome structure of the thermophilic cyanobacterium
RT   Thermosynechococcus elongatus BP-1.";
RL   DNA Res. 9:123-130(2002).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420;
CC         Evidence={ECO:0000255|HAMAP-Rule:MF_00490};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000255|HAMAP-
CC       Rule:MF_00490}.
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DR   EMBL; BA000039; BAC07955.1; -; Genomic_DNA.
DR   RefSeq; NP_681193.1; NC_004113.1.
DR   RefSeq; WP_011056258.1; NC_004113.1.
DR   AlphaFoldDB; Q8DLS5; -.
DR   SMR; Q8DLS5; -.
DR   STRING; 197221.22294124; -.
DR   PRIDE; Q8DLS5; -.
DR   EnsemblBacteria; BAC07955; BAC07955; BAC07955.
DR   KEGG; tel:tll0403; -.
DR   PATRIC; fig|197221.4.peg.426; -.
DR   eggNOG; COG2045; Bacteria.
DR   OMA; RLFMSTT; -.
DR   OrthoDB; 1617556at2; -.
DR   Proteomes; UP000000440; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium; Reference proteome.
FT   CHAIN           1..244
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_0000081474"
SQ   SEQUENCE   244 AA;  26737 MW;  5111FE80D00EC7F9 CRC64;
     MKIYTYHTPE RVPADWQPDC AIAVDVLRAT TTIATALAAG AEAVQVFSDL TELEQVSQQW
     PAAKRIRVGE RGGKKVAGFD MGNSPAECLP ERVRGCRLFM STTNGTRSLE RIQASPLVLA
     AALVNRAAVA EFVQKHQPET VWIVGSGWEG SYSLEDTVCA GALIHYLWGQ QDAPLETLAG
     NDETIAATAL YRYYQDDLLT LFHHSSHGQR LLNLGNEADL KYCAQVDILA IVPWQVSPKL
     LTKA