ID   COMB_THEVO              Reviewed;         212 AA.
AC   Q97CK6;
DT   05-DEC-2001, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-2001, sequence version 1.
DT   25-MAY-2022, entry version 101.
DE   RecName: Full=Probable 2-phosphosulfolactate phosphatase;
DE            EC=3.1.3.71;
GN   Name=comB; OrderedLocusNames=TV0095; ORFNames=TVG0100132;
OS   Thermoplasma volcanium (strain ATCC 51530 / DSM 4299 / JCM 9571 / NBRC
OS   15438 / GSS1).
OC   Archaea; Candidatus Thermoplasmatota; Thermoplasmata; Thermoplasmatales;
OC   Thermoplasmataceae; Thermoplasma.
OX   NCBI_TaxID=273116;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51530 / DSM 4299 / JCM 9571 / NBRC 15438 / GSS1;
RX   PubMed=11121031; DOI=10.1073/pnas.97.26.14257;
RA   Kawashima T., Amano N., Koike H., Makino S., Higuchi S., Kawashima-Ohya Y.,
RA   Watanabe K., Yamazaki M., Kanehori K., Kawamoto T., Nunoshiba T.,
RA   Yamamoto Y., Aramaki H., Makino K., Suzuki M.;
RT   "Archaeal adaptation to higher temperatures revealed by genomic sequence of
RT   Thermoplasma volcanium.";
RL   Proc. Natl. Acad. Sci. U.S.A. 97:14257-14262(2000).
CC   -!- CATALYTIC ACTIVITY:
CC       Reaction=(2R)-O-phospho-3-sulfolactate + H2O = (2R)-3-sulfolactate +
CC         phosphate; Xref=Rhea:RHEA:23416, ChEBI:CHEBI:15377,
CC         ChEBI:CHEBI:15597, ChEBI:CHEBI:43474, ChEBI:CHEBI:58738; EC=3.1.3.71;
CC   -!- COFACTOR:
CC       Name=Mg(2+); Xref=ChEBI:CHEBI:18420; Evidence={ECO:0000250};
CC   -!- SIMILARITY: Belongs to the ComB family. {ECO:0000305}.
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DR   EMBL; BA000011; BAB59237.1; -; Genomic_DNA.
DR   RefSeq; WP_010916352.1; NC_002689.2.
DR   AlphaFoldDB; Q97CK6; -.
DR   SMR; Q97CK6; -.
DR   STRING; 273116.14324309; -.
DR   EnsemblBacteria; BAB59237; BAB59237; BAB59237.
DR   GeneID; 1441582; -.
DR   KEGG; tvo:TVG0100132; -.
DR   eggNOG; arCOG04871; Archaea.
DR   HOGENOM; CLU_070028_0_0_2; -.
DR   OMA; CAQYIAR; -.
DR   OrthoDB; 84054at2157; -.
DR   PhylomeDB; Q97CK6; -.
DR   Proteomes; UP000001017; Chromosome.
DR   GO; GO:0050532; F:2-phosphosulfolactate phosphatase activity; IEA:UniProtKB-UniRule.
DR   GO; GO:0000287; F:magnesium ion binding; IEA:UniProtKB-UniRule.
DR   Gene3D; 3.90.1560.10; -; 1.
DR   HAMAP; MF_00490; ComB; 1.
DR   InterPro; IPR005238; ComB-like.
DR   InterPro; IPR036702; ComB-like_sf.
DR   PANTHER; PTHR37311; PTHR37311; 1.
DR   Pfam; PF04029; 2-ph_phosp; 1.
DR   SUPFAM; SSF142823; SSF142823; 1.
PE   3: Inferred from homology;
KW   Hydrolase; Magnesium.
FT   CHAIN           1..212
FT                   /note="Probable 2-phosphosulfolactate phosphatase"
FT                   /id="PRO_0000081462"
SQ   SEQUENCE   212 AA;  23936 MW;  D67465756C8C4A29 CRC64;
     MIRIADGRKE ENWSSINIII DIFRSTTTIP VILSRGARYI VPFKDVTSAL NFKRKNKNVV
     LIGEKYGIKP PFFDYDNSPA QIINADLEGK IIAFTSTNGM YVLSRIKRGR ILFSSLVNMS
     ATIKKVKGKD DILVVPSNRP IGKAVEDNIF AEMLKLALEG KNYDREILVN RIRETKENTV
     VSISTQDLEI CLKLDLLDCV PEYIEGKIVN DP