ID   COMCA_BPT4              Reviewed;         141 AA.
AC   Q01438;
DT   01-OCT-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-OCT-1993, sequence version 1.
DT   25-MAY-2022, entry version 68.
DE   RecName: Full=Protein comC-alpha;
GN   Name=comCA; Synonyms=gof;
OS   Enterobacteria phage T4 (Bacteriophage T4).
OC   Viruses; Duplodnaviria; Heunggongvirae; Uroviricota; Caudoviricetes;
OC   Caudovirales; Myoviridae; Tevenvirinae; Tequatrovirus.
OX   NCBI_TaxID=10665;
OH   NCBI_TaxID=562; Escherichia coli.
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1400206; DOI=10.1128/jb.174.20.6539-6547.1992;
RA   Sanson B., Uzan M.;
RT   "Sequence and characterization of the bacteriophage T4 comC alpha gene
RT   product, a possible transcription antitermination factor.";
RL   J. Bacteriol. 174:6539-6547(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RX   PubMed=12626685; DOI=10.1128/mmbr.67.1.86-156.2003;
RA   Miller E.S., Kutter E., Mosig G., Arisaka F., Kunisawa T., Ruger W.;
RT   "Bacteriophage T4 genome.";
RL   Microbiol. Mol. Biol. Rev. 67:86-156(2003).
RN   [3]
RP   FUNCTION.
RX   PubMed=2544560; DOI=10.1128/jb.171.7.3872-3880.1989;
RA   Stitt B.L., Mosig G.;
RT   "Impaired expression of certain prereplicative bacteriophage T4 genes
RT   explains impaired T4 DNA synthesis in Escherichia coli rho (nusD)
RT   mutants.";
RL   J. Bacteriol. 171:3872-3880(1989).
RN   [4]
RP   FUNCTION.
RX   PubMed=2668290; DOI=10.1016/s0021-9258(18)71698-0;
RA   Hinton D.M.;
RT   "Altered expression of the bacteriophage T4 gene 41 (primase-helicase) in
RT   an Escherichia coli rho mutant.";
RL   J. Biol. Chem. 264:14440-14446(1989).
CC   -!- FUNCTION: Plays a role in the expression of some T4 genes involved in
CC       DNA synthesis including the helicase/primase gp41. May act as a
CC       transcriptional antitermination factor. {ECO:0000269|PubMed:2544560,
CC       ECO:0000269|PubMed:2668290}.
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DR   EMBL; M89919; AAA32485.1; -; Genomic_DNA.
DR   EMBL; AF158101; AAD42552.1; -; Genomic_DNA.
DR   PIR; A45731; A45731.
DR   RefSeq; NP_049624.1; NC_000866.4.
DR   GeneID; 1258632; -.
DR   KEGG; vg:1258632; -.
DR   Proteomes; UP000009087; Genome.
PE   4: Predicted;
KW   Reference proteome; Transcription; Transcription regulation.
FT   CHAIN           1..141
FT                   /note="Protein comC-alpha"
FT                   /id="PRO_0000164924"
SQ   SEQUENCE   141 AA;  16682 MW;  96C9EFA8C673C479 CRC64;
     MAIKFEVNKW YQFKNKQAQE NFIKDHTDNG IYARRLGMEP FKILDADYLG RPTKIMTSIG
     VLKRCAGGDI LDENFIWLST NEAGFFDEVE NPYQAVEEQE QEEKEQEQIE DFTEFPVMKV
     TIENNDQAWS LYQMLKAYFK E