ID   COMD1_DICDI             Reviewed;         187 AA.
AC   Q54DR0;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   24-MAY-2005, sequence version 1.
DT   25-MAY-2022, entry version 72.
DE   RecName: Full=COMM domain-containing protein 1;
GN   Name=commd1; ORFNames=DDB_G0292074;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000187; EAL61393.1; -; Genomic_DNA.
DR   RefSeq; XP_629812.1; XM_629810.1.
DR   AlphaFoldDB; Q54DR0; -.
DR   STRING; 44689.DDB0266452; -.
DR   PaxDb; Q54DR0; -.
DR   EnsemblProtists; EAL61393; EAL61393; DDB_G0292074.
DR   GeneID; 8628493; -.
DR   KEGG; ddi:DDB_G0292074; -.
DR   dictyBase; DDB_G0292074; commd1.
DR   eggNOG; ENOG502RC3T; Eukaryota.
DR   HOGENOM; CLU_124698_0_0_1; -.
DR   InParanoid; Q54DR0; -.
DR   OMA; SWRIDIK; -.
DR   PhylomeDB; Q54DR0; -.
DR   Reactome; R-DDI-8951664; Neddylation.
DR   PRO; PR:Q54DR0; -.
DR   Proteomes; UP000002195; Chromosome 6.
DR   GO; GO:0005768; C:endosome; IBA:GO_Central.
DR   GO; GO:0005507; F:copper ion binding; ISS:UniProtKB.
DR   GO; GO:0055070; P:copper ion homeostasis; IBA:GO_Central.
DR   GO; GO:2000009; P:negative regulation of protein localization to cell surface; IBA:GO_Central.
DR   GO; GO:1902306; P:negative regulation of sodium ion transmembrane transport; IBA:GO_Central.
DR   GO; GO:0031398; P:positive regulation of protein ubiquitination; IBA:GO_Central.
DR   GO; GO:0032434; P:regulation of proteasomal ubiquitin-dependent protein catabolic process; IBA:GO_Central.
DR   InterPro; IPR017920; COMM.
DR   InterPro; IPR033776; COMMD1_N.
DR   InterPro; IPR037351; Murr1.
DR   PANTHER; PTHR21199; PTHR21199; 1.
DR   Pfam; PF07258; COMM_domain; 1.
DR   Pfam; PF17221; COMMD1_N; 1.
DR   PROSITE; PS51269; COMM; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..187
FT                   /note="COMM domain-containing protein 1"
FT                   /id="PRO_0000327451"
FT   DOMAIN          112..186
FT                   /note="COMM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00602"
SQ   SEQUENCE   187 AA;  22224 MW;  82E119CB72020CE8 CRC64;
     MDQPKYFSSL LGFLLKKEYE KDEDCKSLET LKEMVFSEQD DVTLELIEFT YNKCFEIIQK
     ASYSDMQIST FENIVKESDF TTVQQECLNK FWKVNKKKIH EIIYKTTRFN NSLQKISWRI
     DVKTKSKEIS EINEPVSIVE LKLKNTNTNN NNNNKNDLIR FEMDKNQLEE TLQQINSIQK
     HLQAKSL