ID   COMD7_DICDI             Reviewed;         209 AA.
AC   Q86I14; Q554E1;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   01-JUN-2003, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=COMM domain-containing protein 7;
GN   Name=commd7; ORFNames=DDB_G0275055;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
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DR   EMBL; AAFI02000013; EAL69808.1; -; Genomic_DNA.
DR   RefSeq; XP_643770.1; XM_638678.1.
DR   AlphaFoldDB; Q86I14; -.
DR   STRING; 44689.DDB0266458; -.
DR   PaxDb; Q86I14; -.
DR   EnsemblProtists; EAL69808; EAL69808; DDB_G0275055.
DR   GeneID; 8619815; -.
DR   KEGG; ddi:DDB_G0275055; -.
DR   dictyBase; DDB_G0275055; commd7.
DR   eggNOG; ENOG502QQ17; Eukaryota.
DR   HOGENOM; CLU_118172_0_0_1; -.
DR   InParanoid; Q86I14; -.
DR   OMA; SQMENVY; -.
DR   PhylomeDB; Q86I14; -.
DR   Reactome; R-DDI-8951664; Neddylation.
DR   PRO; PR:Q86I14; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0051059; F:NF-kappaB binding; IBA:GO_Central.
DR   GO; GO:0032088; P:negative regulation of NF-kappaB transcription factor activity; IBA:GO_Central.
DR   GO; GO:0045892; P:negative regulation of transcription, DNA-templated; IBA:GO_Central.
DR   GO; GO:0033209; P:tumor necrosis factor-mediated signaling pathway; IBA:GO_Central.
DR   CDD; cd04755; Commd7; 1.
DR   InterPro; IPR017920; COMM.
DR   InterPro; IPR037358; COMMD7.
DR   Pfam; PF07258; COMM_domain; 1.
DR   PROSITE; PS51269; COMM; 1.
PE   4: Predicted;
KW   Reference proteome.
FT   CHAIN           1..209
FT                   /note="COMM domain-containing protein 7"
FT                   /id="PRO_0000327466"
FT   DOMAIN          138..209
FT                   /note="COMM"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00602"
SQ   SEQUENCE   209 AA;  24396 MW;  036B1E8A684861FA CRC64;
     MVFRFLGNNN NNNNELPDQQ LINEIGYLSN FSNEQLEQLL DIIFEFMIIQ KSEQLLNQIQ
     EFSNEHSINE NTLKNIIRGC IIFFKSSAKN NLTIDHLRED CIQFKLDEEQ SKLVSTKYKQ
     HYIEISRSLV GNSLTINQVL DMQWRFGVTT SSSEFTKSNT TGSTFLQLKL VLDKGNNIKE
     DVHMELTLPQ FYEFLKEMQS AKASLEYFN