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COMFC_BACSU
ID   COMFC_BACSU             Reviewed;         229 AA.
AC   P39147;
DT   01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-FEB-1995, sequence version 1.
DT   03-AUG-2022, entry version 119.
DE   RecName: Full=ComF operon protein 3;
GN   Name=comFC; Synonyms=comF3; OrderedLocusNames=BSU35450;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=8412657; DOI=10.1111/j.1365-2958.1993.tb01674.x;
RA   Londono-Vallejo J.A., Dubnau D.;
RT   "comF, a Bacillus subtilis late competence locus, encodes a protein similar
RT   to ATP-dependent RNA/DNA helicases.";
RL   Mol. Microbiol. 9:119-131(1993).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=8045879; DOI=10.1128/jb.176.15.4492-4500.1994;
RA   Mirel D.B., Lauer P., Chamberlin M.J.;
RT   "Identification of flagellar synthesis regulatory and structural genes in a
RT   sigma D-dependent operon of Bacillus subtilis.";
RL   J. Bacteriol. 176:4492-4500(1994).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=8969505; DOI=10.1099/13500872-142-11-3079;
RA   Soldo B., Lazarevic V., Mauel C., Karamata D.;
RT   "Sequence of the 305 degrees-307 degrees region of the Bacillus subtilis
RT   chromosome.";
RL   Microbiology 142:3079-3088(1996).
RN   [4]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
CC   -!- FUNCTION: Involved in transformation (competence for DNA uptake).
CC   -!- SIMILARITY: Belongs to the ComF/GntX family. {ECO:0000305}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAB59015.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; Z18629; CAA79228.1; -; Genomic_DNA.
DR   EMBL; L14437; AAB59015.1; ALT_INIT; Genomic_DNA.
DR   EMBL; U56901; AAC44942.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB15562.1; -; Genomic_DNA.
DR   PIR; S77621; S77621.
DR   RefSeq; NP_391425.1; NC_000964.3.
DR   AlphaFoldDB; P39147; -.
DR   STRING; 224308.BSU35450; -.
DR   PaxDb; P39147; -.
DR   PRIDE; P39147; -.
DR   DNASU; 936747; -.
DR   EnsemblBacteria; CAB15562; CAB15562; BSU_35450.
DR   GeneID; 936747; -.
DR   KEGG; bsu:BSU35450; -.
DR   PATRIC; fig|224308.43.peg.3711; -.
DR   eggNOG; COG1040; Bacteria.
DR   InParanoid; P39147; -.
DR   OMA; DYFSRYK; -.
DR   PhylomeDB; P39147; -.
DR   BioCyc; BSUB:BSU35450-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   InterPro; IPR005222; Competence_ComF.
DR   InterPro; IPR044005; DZR_2.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   Pfam; PF18912; DZR_2; 1.
DR   SUPFAM; SSF53271; SSF53271; 1.
DR   TIGRFAMs; TIGR00201; comF; 1.
PE   3: Inferred from homology;
KW   Competence; Reference proteome.
FT   CHAIN           1..229
FT                   /note="ComF operon protein 3"
FT                   /id="PRO_0000209457"
SQ   SEQUENCE   229 AA;  26414 MW;  EC355E2ECF034503 CRC64;
     MICLLCDSQF SQDVTWRALF LLKPDEKVCY SCRSKLKKIT GHICPLCGRP QSVHAVCRDC
     EVWRTRIRDS LLLRQNRSVY TYNDMMKETL SRFKFRGDAE IINAFKSDFS STFSKVYPDK
     HFVLVPIPLS KEREEERGFN QAHLLAECLD RPSHHPLIRL NNEKQSKKKK TERLLSECIF
     DTKNNSAEGM NIILIDDLYT TGATLHFAAR CLLEKGKAAS VSSFTLIRS
 
 
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