ID   COMF_HAEIN              Reviewed;         229 AA.
AC   P31773;
DT   01-JUL-1993, integrated into UniProtKB/Swiss-Prot.
DT   01-JUL-1993, sequence version 1.
DT   03-AUG-2022, entry version 101.
DE   RecName: Full=Competence protein F;
DE   AltName: Full=DNA transformation protein ComF;
DE   AltName: Full=Protein COM101A;
GN   Name=comF; OrderedLocusNames=HI_0434;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=1916268; DOI=10.1016/0378-1119(91)90457-m;
RA   Tomb J.-F., El-Hajj H., Smith H.O.;
RT   "Nucleotide sequence of a cluster of genes involved in the transformation
RT   of Haemophilus influenzae Rd.";
RL   Gene 104:1-10(1991).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1856167; DOI=10.1128/jb.173.15.4683-4691.1991;
RA   Larson T.G., Goodgal S.H.;
RT   "Sequence and transcriptional regulation of com101A, a locus required for
RT   genetic transformation in Haemophilus influenzae.";
RL   J. Bacteriol. 173:4683-4691(1991).
RN   [3]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
CC   -!- FUNCTION: Involved in transformation (competence for DNA uptake).
CC   -!- SIMILARITY: Belongs to the ComF/GntX family. {ECO:0000305}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; M62809; AAA25014.1; -; Genomic_DNA.
DR   EMBL; M59751; AAA24949.1; -; Genomic_DNA.
DR   EMBL; L42023; AAC22093.1; -; Genomic_DNA.
DR   PIR; JH0435; JH0435.
DR   RefSeq; NP_438595.1; NC_000907.1.
DR   AlphaFoldDB; P31773; -.
DR   STRING; 71421.HI_0434; -.
DR   EnsemblBacteria; AAC22093; AAC22093; HI_0434.
DR   KEGG; hin:HI_0434; -.
DR   PATRIC; fig|71421.8.peg.454; -.
DR   eggNOG; COG1040; Bacteria.
DR   HOGENOM; CLU_054549_0_2_6; -.
DR   OMA; RYNQSAL; -.
DR   PhylomeDB; P31773; -.
DR   BioCyc; HINF71421:G1GJ1-449-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR   CDD; cd06223; PRTases_typeI; 1.
DR   Gene3D; 3.40.50.2020; -; 1.
DR   InterPro; IPR005222; Competence_ComF.
DR   InterPro; IPR000836; PRibTrfase_dom.
DR   InterPro; IPR029057; PRTase-like.
DR   Pfam; PF00156; Pribosyltran; 1.
DR   SUPFAM; SSF53271; SSF53271; 1.
DR   TIGRFAMs; TIGR00201; comF; 1.
PE   3: Inferred from homology;
KW   Competence; Reference proteome.
FT   CHAIN           1..229
FT                   /note="Competence protein F"
FT                   /id="PRO_0000209456"
SQ   SEQUENCE   229 AA;  26791 MW;  2F5B72B6C8C79503 CRC64;
     MMNFFNFRCI HCRGNLHIAK NGLCSGCQKQ IKSFPYCGHC GSELQYYAQH CGNCLKQEPS
     WDKMVIIGHY IEPLSILIQR FKFQNQFWID RTLARLLYLA VRDAKRTHQL KLPEAIIPVP
     LYHFRQWRRG YNQADLLSQQ LSRWLDIPNL NNIVKRVKHT YTQRGLSAKD RRQNLKNAFS
     LAVSKNEFPY RRVALVDDVI TTGSTLNEIS KLLRKLGVEE IQVWGLARA