ID   COMGF_BACSU             Reviewed;         127 AA.
AC   P25958; O32021;
DT   01-MAY-1992, integrated into UniProtKB/Swiss-Prot.
DT   30-MAY-2000, sequence version 2.
DT   03-AUG-2022, entry version 97.
DE   RecName: Full=ComG operon protein 6;
GN   Name=comGF; Synonyms=comG6; OrderedLocusNames=BSU24680;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=2507524; DOI=10.1128/jb.171.10.5386-5404.1989;
RA   Albano M., Breitling R., Dubnau D.A.;
RT   "Nucleotide sequence and genetic organization of the Bacillus subtilis comG
RT   operon.";
RL   J. Bacteriol. 171:5386-5404(1989).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   FUNCTION.
RX   PubMed=9422590; DOI=10.1128/jb.180.1.41-45.1998;
RA   Chung Y.S., Dubnau D.A.;
RT   "All seven comG open reading frames are required for DNA binding during
RT   transformation of competent Bacillus subtilis.";
RL   J. Bacteriol. 180:41-45(1998).
RN   [4]
RP   SUBCELLULAR LOCATION.
RX   PubMed=9723928; DOI=10.1046/j.1365-2958.1998.00989.x;
RA   Chung Y.S., Breidt F., Dubnau D.A.;
RT   "Cell surface localization and processing of the ComG proteins, required
RT   for DNA binding during transformation of Bacillus subtilis.";
RL   Mol. Microbiol. 29:905-913(1998).
CC   -!- FUNCTION: Required for transformation and DNA binding.
CC       {ECO:0000269|PubMed:9422590}.
CC   -!- SUBCELLULAR LOCATION: Cell membrane {ECO:0000269|PubMed:9723928};
CC       Peripheral membrane protein {ECO:0000269|PubMed:9723928}.
CC   -!- SEQUENCE CAUTION:
CC       Sequence=AAA83372.1; Type=Erroneous initiation; Evidence={ECO:0000305};
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DR   EMBL; M29691; AAA83372.1; ALT_INIT; Genomic_DNA.
DR   EMBL; AL009126; CAB14399.1; -; Genomic_DNA.
DR   PIR; G30338; G30338.
DR   PIR; G69603; G69603.
DR   RefSeq; NP_390348.1; NC_000964.3.
DR   RefSeq; WP_003230168.1; NZ_JNCM01000036.1.
DR   AlphaFoldDB; P25958; -.
DR   STRING; 224308.BSU24680; -.
DR   PaxDb; P25958; -.
DR   PRIDE; P25958; -.
DR   EnsemblBacteria; CAB14399; CAB14399; BSU_24680.
DR   GeneID; 938530; -.
DR   KEGG; bsu:BSU24680; -.
DR   PATRIC; fig|224308.179.peg.2686; -.
DR   eggNOG; COG4940; Bacteria.
DR   OMA; QMMNECK; -.
DR   BioCyc; BSUB:BSU24680-MON; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0005886; C:plasma membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR   InterPro; IPR016977; Competence_ComGF.
DR   Pfam; PF15980; ComGF; 1.
DR   PIRSF; PIRSF031611; Competence_ComGF; 1.
PE   4: Predicted;
KW   Cell membrane; Competence; Membrane; Reference proteome.
FT   CHAIN           1..127
FT                   /note="ComG operon protein 6"
FT                   /id="PRO_0000090011"
SQ   SEQUENCE   127 AA;  14281 MW;  6598AA28873AD84F CRC64;
     MLISGSLAAI IHLFLSRQQE HDGFTQQEWM ISIEQMMNEC KESQAVKTAE HGSVLICTNL
     SGQDIRFDIY HSMIRKRVDG KGHVPILDHI TAMKADIENG VVLLKIESED QKVYQTAFPV
     YSYLGGG