ID   COMM_HAEIN              Reviewed;         509 AA.
AC   P45049;
DT   01-NOV-1995, integrated into UniProtKB/Swiss-Prot.
DT   01-NOV-1995, sequence version 1.
DT   03-AUG-2022, entry version 127.
DE   RecName: Full=Competence protein ComM;
GN   Name=comM; OrderedLocusNames=HI_1117;
OS   Haemophilus influenzae (strain ATCC 51907 / DSM 11121 / KW20 / Rd).
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Pasteurellales;
OC   Pasteurellaceae; Haemophilus.
OX   NCBI_TaxID=71421;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=7542800; DOI=10.1126/science.7542800;
RA   Fleischmann R.D., Adams M.D., White O., Clayton R.A., Kirkness E.F.,
RA   Kerlavage A.R., Bult C.J., Tomb J.-F., Dougherty B.A., Merrick J.M.,
RA   McKenney K., Sutton G.G., FitzHugh W., Fields C.A., Gocayne J.D.,
RA   Scott J.D., Shirley R., Liu L.-I., Glodek A., Kelley J.M., Weidman J.F.,
RA   Phillips C.A., Spriggs T., Hedblom E., Cotton M.D., Utterback T.R.,
RA   Hanna M.C., Nguyen D.T., Saudek D.M., Brandon R.C., Fine L.D.,
RA   Fritchman J.L., Fuhrmann J.L., Geoghagen N.S.M., Gnehm C.L., McDonald L.A.,
RA   Small K.V., Fraser C.M., Smith H.O., Venter J.C.;
RT   "Whole-genome random sequencing and assembly of Haemophilus influenzae
RT   Rd.";
RL   Science 269:496-512(1995).
RN   [2]
RP   CHARACTERIZATION.
RC   STRAIN=ATCC 51907 / DSM 11121 / KW20 / Rd;
RX   PubMed=9457884; DOI=10.1128/jb.180.3.746-748.1998;
RA   Gwinn M.L., Ramanathan R., Smith H.O., Tomb J.-F.;
RT   "A new transformation-deficient mutant of Haemophilus influenzae Rd with
RT   normal DNA uptake.";
RL   J. Bacteriol. 180:746-748(1998).
CC   -!- FUNCTION: Induced during competence development. Not needed for DNA
CC       uptake. May be involved in a recombination step.
CC   -!- SIMILARITY: Belongs to the Mg-chelatase subunits D/I family. ComM
CC       subfamily. {ECO:0000305}.
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DR   EMBL; L42023; AAC22771.1; -; Genomic_DNA.
DR   PIR; I64183; I64183.
DR   RefSeq; NP_439274.1; NC_000907.1.
DR   RefSeq; WP_010869133.1; NC_000907.1.
DR   AlphaFoldDB; P45049; -.
DR   STRING; 71421.HI_1117; -.
DR   EnsemblBacteria; AAC22771; AAC22771; HI_1117.
DR   KEGG; hin:HI_1117; -.
DR   PATRIC; fig|71421.8.peg.1166; -.
DR   eggNOG; COG0606; Bacteria.
DR   HOGENOM; CLU_026145_1_1_6; -.
DR   OMA; STNPCPC; -.
DR   PhylomeDB; P45049; -.
DR   BioCyc; HINF71421:G1GJ1-1152-MON; -.
DR   Proteomes; UP000000579; Chromosome.
DR   GO; GO:0005524; F:ATP binding; IEA:UniProtKB-KW.
DR   GO; GO:0003677; F:DNA binding; IEA:InterPro.
DR   GO; GO:0032508; P:DNA duplex unwinding; IEA:InterPro.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR   Gene3D; 3.30.230.10; -; 1.
DR   Gene3D; 3.40.50.300; -; 1.
DR   InterPro; IPR003593; AAA+_ATPase.
DR   InterPro; IPR045006; CHLI-like.
DR   InterPro; IPR001208; MCM_dom.
DR   InterPro; IPR004482; Mg_chelat-rel.
DR   InterPro; IPR025158; Mg_chelat-rel_C.
DR   InterPro; IPR000523; Mg_chelatse_chII-like_cat_dom.
DR   InterPro; IPR027417; P-loop_NTPase.
DR   InterPro; IPR020568; Ribosomal_S5_D2-typ_fold.
DR   InterPro; IPR014721; Ribosomal_S5_D2-typ_fold_subgr.
DR   PANTHER; PTHR32039; PTHR32039; 1.
DR   PANTHER; PTHR32039:SF7; PTHR32039:SF7; 1.
DR   Pfam; PF01078; Mg_chelatase; 1.
DR   Pfam; PF13335; Mg_chelatase_C; 1.
DR   PRINTS; PR01657; MCMFAMILY.
DR   SMART; SM00382; AAA; 1.
DR   SUPFAM; SSF52540; SSF52540; 1.
DR   SUPFAM; SSF54211; SSF54211; 1.
DR   TIGRFAMs; TIGR00368; TIGR00368; 1.
PE   1: Evidence at protein level;
KW   ATP-binding; Competence; Nucleotide-binding; Reference proteome.
FT   CHAIN           1..509
FT                   /note="Competence protein ComM"
FT                   /id="PRO_0000206876"
FT   BINDING         222..229
FT                   /ligand="ATP"
FT                   /ligand_id="ChEBI:CHEBI:30616"
FT                   /evidence="ECO:0000255"
SQ   SEQUENCE   509 AA;  55915 MW;  9CA5F217CD64305A CRC64;
     MSLAIVYSRA SMGVQAPLVT IEVHLSNGKP GFTLVGLPEK TVKEAQDRVR SALMNAQFKY
     PAKRITVNLA PADLPKEGGR FDLPIAIGIL AASDQLDASH LKQFEFVAEL ALTGQLRGVH
     GVIPAILAAQ KSKRELIIAK QNANEASLVS DQNTYFAQTL LDVVQFLNGQ EKLPLATEIV
     KESAVNFSGK NTLDLTDIIG QQHAKRALTI AAAGQHNLLF LGPPGTGKTM LASRLTGLLP
     EMTDLEAIET ASVTSLVQNE LNFHNWKQRP FRAPHHSASM PALVGGGTIP KPGEISLATN
     GVLFLDELPE FERKVLDALR QPLESGEIII SRANAKIQFP ARFQLVAAMN PSPTGHYTGT
     HNRTSPQQIM RYLNRLSGPF LDRFDLSIEV PLLPQGSLQN TGDRGETSAQ VREKVLKVRE
     IQMERAGKIN AYLNSKEIER DCKLNDKDAF FLEKALNKLG LSVRAYHRIL KVSRTIADLQ
     GEQQIFQPHL AEALGYRAMV RLLQKLSNM