COMS_BACSU
ID COMS_BACSU Reviewed; 46 AA.
AC P80355;
DT 01-FEB-1995, integrated into UniProtKB/Swiss-Prot.
DT 01-FEB-1995, sequence version 1.
DT 03-AUG-2022, entry version 85.
DE RecName: Full=Competence protein S;
GN Name=comS; OrderedLocusNames=BSU03500;
OS Bacillus subtilis (strain 168).
OC Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX NCBI_TaxID=224308;
RN [1]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND CHARACTERIZATION.
RC STRAIN=168 / 8G5;
RX PubMed=7752896; DOI=10.1111/j.1365-2958.1995.tb02220.x;
RA Hamoen L.W., Eshuis H., Jongbloed J., Venema G., van Sinderen D.;
RT "A small gene, designated comS, located within the coding region of the
RT fourth amino acid-activation domain of srfA, is required for competence
RT development in Bacillus subtilis.";
RL Mol. Microbiol. 15:55-63(1995).
RN [2]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA], AND CHARACTERIZATION.
RC STRAIN=168;
RX PubMed=7937777; DOI=10.1073/pnas.91.20.9397;
RA D'Souza C., Nakano M.M., Zuber P.;
RT "Identification of comS, a gene of the srfA operon that regulates the
RT establishment of genetic competence in Bacillus subtilis.";
RL Proc. Natl. Acad. Sci. U.S.A. 91:9397-9401(1994).
RN [3]
RP ERRATUM OF PUBMED:7937777.
RX PubMed=7831343; DOI=10.1073/pnas.92.2.646-f;
RA D'Souza C., Nakano M.M., Zuber P.;
RL Proc. Natl. Acad. Sci. U.S.A. 92:646-646(1995).
RN [4]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=8441623; DOI=10.1093/nar/21.1.93;
RA Fuma S., Fujishima Y., Corbell N., D'Souza C., Nakano M.M., Zuber P.,
RA Yamane K.;
RT "Nucleotide sequence of 5' portion of srfA that contains the region
RT required for competence establishment in Bacillus subtilis.";
RL Nucleic Acids Res. 21:93-97(1993).
RN [5]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168 / JH642;
RX PubMed=8355609; DOI=10.1111/j.1365-2958.1993.tb01629.x;
RA Cosmina P., Rodriguez F., de Ferra F., Grandi G., Perego M., Venema G.,
RA van Sinderen D.;
RT "Sequence and analysis of the genetic locus responsible for surfactin
RT synthesis in Bacillus subtilis.";
RL Mol. Microbiol. 8:821-831(1993).
RN [6]
RP NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC STRAIN=168;
RX PubMed=8969502; DOI=10.1099/13500872-142-11-3047;
RA Yamane K., Kumano M., Kurita K.;
RT "The 25 degrees-36 degrees region of the Bacillus subtilis chromosome:
RT determination of the sequence of a 146 kb segment and identification of 113
RT genes.";
RL Microbiology 142:3047-3056(1996).
RN [7]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=168;
RX PubMed=9384377; DOI=10.1038/36786;
RA Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA Yoshikawa H., Danchin A.;
RT "The complete genome sequence of the Gram-positive bacterium Bacillus
RT subtilis.";
RL Nature 390:249-256(1997).
CC -!- FUNCTION: Required for the development of competence.
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DR EMBL; U10926; AAA61567.1; -; Genomic_DNA.
DR EMBL; D13262; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; X70356; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; X72672; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; D50453; BAA08984.1; -; Genomic_DNA.
DR EMBL; AL009126; CAB12144.1; -; Genomic_DNA.
DR PIR; S65598; S65598.
DR RefSeq; NP_388232.1; NC_000964.3.
DR RefSeq; WP_010886404.1; NC_000964.3.
DR AlphaFoldDB; P80355; -.
DR STRING; 224308.BSU03500; -.
DR EnsemblBacteria; CAB12144; CAB12144; BSU_03500.
DR GeneID; 938310; -.
DR KEGG; bsu:BSU03500; -.
DR BioCyc; BSUB:BSU03500-MON; -.
DR Proteomes; UP000001570; Chromosome.
DR GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR InterPro; IPR035139; ComS.
DR Pfam; PF17584; ComS; 1.
PE 1: Evidence at protein level;
KW Competence; Reference proteome.
FT CHAIN 1..46
FT /note="Competence protein S"
FT /id="PRO_0000090015"
SQ SEQUENCE 46 AA; 5244 MW; F2ADBE7BA7CFDB9F CRC64;
MNRSGKHLIS SIILYPRPSG ECISSISLDK QTQATTSPLY FCWREK
