ID   COMZ_BACSU              Reviewed;          63 AA.
AC   O32437; O34395;
DT   25-JUL-2003, integrated into UniProtKB/Swiss-Prot.
DT   25-JUL-2003, sequence version 2.
DT   03-AUG-2022, entry version 94.
DE   RecName: Full=ComG operon repressor;
GN   Name=comZ; OrderedLocusNames=BSU11310;
OS   Bacillus subtilis (strain 168).
OC   Bacteria; Firmicutes; Bacilli; Bacillales; Bacillaceae; Bacillus.
OX   NCBI_TaxID=224308;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   STRAIN=168 / CU741;
RX   PubMed=9335269; DOI=10.1128/jb.179.20.6244-6253.1997;
RA   Ogura M., Ohshiro Y., Hirao S., Tanaka T.;
RT   "A new Bacillus subtilis gene, med, encodes a positive regulator of comK.";
RL   J. Bacteriol. 179:6244-6253(1997).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=168;
RX   PubMed=9384377; DOI=10.1038/36786;
RA   Kunst F., Ogasawara N., Moszer I., Albertini A.M., Alloni G., Azevedo V.,
RA   Bertero M.G., Bessieres P., Bolotin A., Borchert S., Borriss R.,
RA   Boursier L., Brans A., Braun M., Brignell S.C., Bron S., Brouillet S.,
RA   Bruschi C.V., Caldwell B., Capuano V., Carter N.M., Choi S.-K.,
RA   Codani J.-J., Connerton I.F., Cummings N.J., Daniel R.A., Denizot F.,
RA   Devine K.M., Duesterhoeft A., Ehrlich S.D., Emmerson P.T., Entian K.-D.,
RA   Errington J., Fabret C., Ferrari E., Foulger D., Fritz C., Fujita M.,
RA   Fujita Y., Fuma S., Galizzi A., Galleron N., Ghim S.-Y., Glaser P.,
RA   Goffeau A., Golightly E.J., Grandi G., Guiseppi G., Guy B.J., Haga K.,
RA   Haiech J., Harwood C.R., Henaut A., Hilbert H., Holsappel S., Hosono S.,
RA   Hullo M.-F., Itaya M., Jones L.-M., Joris B., Karamata D., Kasahara Y.,
RA   Klaerr-Blanchard M., Klein C., Kobayashi Y., Koetter P., Koningstein G.,
RA   Krogh S., Kumano M., Kurita K., Lapidus A., Lardinois S., Lauber J.,
RA   Lazarevic V., Lee S.-M., Levine A., Liu H., Masuda S., Mauel C.,
RA   Medigue C., Medina N., Mellado R.P., Mizuno M., Moestl D., Nakai S.,
RA   Noback M., Noone D., O'Reilly M., Ogawa K., Ogiwara A., Oudega B.,
RA   Park S.-H., Parro V., Pohl T.M., Portetelle D., Porwollik S.,
RA   Prescott A.M., Presecan E., Pujic P., Purnelle B., Rapoport G., Rey M.,
RA   Reynolds S., Rieger M., Rivolta C., Rocha E., Roche B., Rose M., Sadaie Y.,
RA   Sato T., Scanlan E., Schleich S., Schroeter R., Scoffone F., Sekiguchi J.,
RA   Sekowska A., Seror S.J., Serror P., Shin B.-S., Soldo B., Sorokin A.,
RA   Tacconi E., Takagi T., Takahashi H., Takemaru K., Takeuchi M.,
RA   Tamakoshi A., Tanaka T., Terpstra P., Tognoni A., Tosato V., Uchiyama S.,
RA   Vandenbol M., Vannier F., Vassarotti A., Viari A., Wambutt R., Wedler E.,
RA   Wedler H., Weitzenegger T., Winters P., Wipat A., Yamamoto H., Yamane K.,
RA   Yasumoto K., Yata K., Yoshida K., Yoshikawa H.-F., Zumstein E.,
RA   Yoshikawa H., Danchin A.;
RT   "The complete genome sequence of the Gram-positive bacterium Bacillus
RT   subtilis.";
RL   Nature 390:249-256(1997).
RN   [3]
RP   FUNCTION.
RX   PubMed=10940045; DOI=10.1128/jb.182.17.4992-4994.2000;
RA   Ogura M., Tanaka T.;
RT   "Bacillus subtilis comZ (yjzA) negatively affects expression of comG but
RT   not comK.";
RL   J. Bacteriol. 182:4992-4994(2000).
CC   -!- FUNCTION: Negatively regulates the transcription of the comG operon.
CC       {ECO:0000269|PubMed:10940045}.
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DR   EMBL; D86376; BAA22929.1; -; Genomic_DNA.
DR   EMBL; AL009126; CAB12972.1; -; Genomic_DNA.
DR   PIR; D69854; D69854.
DR   RefSeq; NP_389013.1; NC_000964.3.
DR   RefSeq; WP_003224559.1; NZ_JNCM01000035.1.
DR   AlphaFoldDB; O32437; -.
DR   SMR; O32437; -.
DR   STRING; 224308.BSU11310; -.
DR   PaxDb; O32437; -.
DR   PRIDE; O32437; -.
DR   EnsemblBacteria; CAB12972; CAB12972; BSU_11310.
DR   GeneID; 64303004; -.
DR   GeneID; 939358; -.
DR   KEGG; bsu:BSU11310; -.
DR   PATRIC; fig|224308.179.peg.1216; -.
DR   eggNOG; ENOG502ZW4E; Bacteria.
DR   OMA; FMQIAMK; -.
DR   BioCyc; BSUB:BSU11310-MON; -.
DR   PRO; PR:O32437; -.
DR   Proteomes; UP000001570; Chromosome.
DR   GO; GO:0030420; P:establishment of competence for transformation; IEA:UniProtKB-KW.
DR   InterPro; IPR024558; ComZ.
DR   Pfam; PF10815; ComZ; 1.
PE   4: Predicted;
KW   Competence; Reference proteome; Repressor; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..63
FT                   /note="ComG operon repressor"
FT                   /id="PRO_0000090017"
FT   VARIANT         3
FT                   /note="H -> Q (in strain: CU741)"
SQ   SEQUENCE   63 AA;  7214 MW;  916C8DB1473EB05B CRC64;
     MQHEKSLEFL QIAMKYLPEA KEQLEKSGIE LSMEAIQPFM NLFTTVMAEA YELGKSDAKS
     ETE