ID   COPA1_ECOLX             Reviewed;          61 AA.
AC   P03854;
DT   21-JUL-1986, integrated into UniProtKB/Swiss-Prot.
DT   21-JUL-1986, sequence version 1.
DT   25-MAY-2022, entry version 49.
DE   RecName: Full=Protein CopA/IncA;
DE   AltName: Full=Protein RepA3;
GN   Name=copA; Synonyms=incA, repA3;
OS   Escherichia coli.
OG   Plasmid IncFII R100 (NR1), and Plasmid IncFII R1.
OC   Bacteria; Proteobacteria; Gammaproteobacteria; Enterobacterales;
OC   Enterobacteriaceae; Escherichia.
OX   NCBI_TaxID=562;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   PLASMID=IncFII R1, and IncFII R100 (NR1);
RX   PubMed=6163994; DOI=10.1038/290794a0;
RA   Rosen J., Ryder T., Ohtsubo H., Ohtsubo E.;
RT   "Role of RNA transcripts in replication incompatibility and copy number
RT   control in antibiotic resistance plasmid derivatives.";
RL   Nature 290:794-797(1981).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RC   PLASMID=IncFII R100 (NR1);
RX   PubMed=3019092; DOI=10.1016/0065-227x(86)90018-3;
RA   Ohtsubo H., Ryder T.B., Maeda Y., Armstrong K., Ohtsubo E.;
RT   "DNA replication of the resistance plasmid R100 and its control.";
RL   Adv. Biophys. 21:115-133(1986).
CC   -!- FUNCTION: Controls the copy number in gene replication.
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DR   EMBL; J01762; AAA92256.1; -; Genomic_DNA.
DR   EMBL; M26840; AAA26066.1; -; Genomic_DNA.
DR   PIR; B93253; QQEC71.
DR   AlphaFoldDB; P03854; -.
DR   SMR; P03854; -.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:UniProtKB-KW.
PE   4: Predicted;
KW   Plasmid; Plasmid copy control.
FT   CHAIN           1..61
FT                   /note="Protein CopA/IncA"
FT                   /id="PRO_0000068288"
SQ   SEQUENCE   61 AA;  7179 MW;  7D0B3539EF043A1D CRC64;
     MWIYRSQKSK NPDNLLQLLR VRKDYRGPLK PYSQQFSYAG SIVICPEKFK TSFCARSFCA
     L