ID   COPR_STRAG              Reviewed;          92 AA.
AC   P24716;
DT   01-MAR-1992, integrated into UniProtKB/Swiss-Prot.
DT   01-MAR-1992, sequence version 1.
DT   25-MAY-2022, entry version 82.
DE   RecName: Full=Plasmid copy control protein CopR;
GN   Name=copR;
OS   Streptococcus agalactiae.
OG   Plasmid pIP501.
OC   Bacteria; Firmicutes; Bacilli; Lactobacillales; Streptococcaceae;
OC   Streptococcus.
OX   NCBI_TaxID=1311;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=1741273; DOI=10.1093/nar/20.3.395;
RA   Brantl S., Behnke D.;
RT   "Copy number control of the streptococcal plasmid pIP501 occurs at three
RT   levels.";
RL   Nucleic Acids Res. 20:395-400(1992).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [GENOMIC DNA].
RX   PubMed=7514148; DOI=10.1016/0378-1119(94)90372-7;
RA   Brantl S., Kummer C., Behnke D.;
RT   "Complete nucleotide sequence of plasmid pGB3631, a derivative of the
RT   Streptococcus agalactiae plasmid pIP501.";
RL   Gene 142:155-156(1994).
CC   -!- FUNCTION: Involved in copy control of plasmid pIP501.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; X62150; CAA44075.1; -; Genomic_DNA.
DR   EMBL; X72021; CAA50904.1; -; Genomic_DNA.
DR   PIR; S22829; S22829.
DR   RefSeq; NP_053001.1; NC_002136.1.
DR   RefSeq; WP_010891345.1; NC_002136.1.
DR   AlphaFoldDB; P24716; -.
DR   GO; GO:0003677; F:DNA binding; IEA:UniProtKB-KW.
DR   GO; GO:0006276; P:plasmid maintenance; IEA:UniProtKB-KW.
DR   CDD; cd00093; HTH_XRE; 1.
DR   Gene3D; 1.10.260.40; -; 1.
DR   InterPro; IPR001387; Cro/C1-type_HTH.
DR   InterPro; IPR010982; Lambda_DNA-bd_dom_sf.
DR   Pfam; PF01381; HTH_3; 1.
DR   SMART; SM00530; HTH_XRE; 1.
DR   SUPFAM; SSF47413; SSF47413; 1.
DR   PROSITE; PS50943; HTH_CROC1; 1.
PE   4: Predicted;
KW   DNA-binding; Plasmid; Plasmid copy control; Transcription;
KW   Transcription regulation.
FT   CHAIN           1..92
FT                   /note="Plasmid copy control protein CopR"
FT                   /id="PRO_0000149724"
FT   DOMAIN          9..62
FT                   /note="HTH cro/C1-type"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   DNA_BIND        20..39
FT                   /note="H-T-H motif"
FT                   /evidence="ECO:0000255|PROSITE-ProRule:PRU00257"
FT   REGION          1..40
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   REGION          63..92
FT                   /note="Disordered"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        1..25
FT                   /note="Basic and acidic residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
FT   COMPBIAS        26..40
FT                   /note="Polar residues"
FT                   /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ   SEQUENCE   92 AA;  10624 MW;  59A7CEAD088DBFE0 CRC64;
     MELAFRESLK KMRGTKSKEK FSQELEMSRS NYSRIESGKS DPTIKTLEQI VKLTNSTLVV
     DLIPNEPTEP EPETEQVTLE LEMEEEKSND FV