COPT6_ARATH
ID COPT6_ARATH Reviewed; 145 AA.
AC Q8GWP3;
DT 02-NOV-2010, integrated into UniProtKB/Swiss-Prot.
DT 01-MAR-2003, sequence version 1.
DT 03-AUG-2022, entry version 91.
DE RecName: Full=Copper transporter 6;
DE Short=AtCOPT6;
GN Name=COPT6; OrderedLocusNames=At2g26975; ORFNames=T20P8;
OS Arabidopsis thaliana (Mouse-ear cress).
OC Eukaryota; Viridiplantae; Streptophyta; Embryophyta; Tracheophyta;
OC Spermatophyta; Magnoliopsida; eudicotyledons; Gunneridae; Pentapetalae;
OC rosids; malvids; Brassicales; Brassicaceae; Camelineae; Arabidopsis.
OX NCBI_TaxID=3702;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=cv. Columbia;
RX PubMed=10617197; DOI=10.1038/45471;
RA Lin X., Kaul S., Rounsley S.D., Shea T.P., Benito M.-I., Town C.D.,
RA Fujii C.Y., Mason T.M., Bowman C.L., Barnstead M.E., Feldblyum T.V.,
RA Buell C.R., Ketchum K.A., Lee J.J., Ronning C.M., Koo H.L., Moffat K.S.,
RA Cronin L.A., Shen M., Pai G., Van Aken S., Umayam L., Tallon L.J.,
RA Gill J.E., Adams M.D., Carrera A.J., Creasy T.H., Goodman H.M.,
RA Somerville C.R., Copenhaver G.P., Preuss D., Nierman W.C., White O.,
RA Eisen J.A., Salzberg S.L., Fraser C.M., Venter J.C.;
RT "Sequence and analysis of chromosome 2 of the plant Arabidopsis thaliana.";
RL Nature 402:761-768(1999).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=cv. Columbia;
RX PubMed=27862469; DOI=10.1111/tpj.13415;
RA Cheng C.Y., Krishnakumar V., Chan A.P., Thibaud-Nissen F., Schobel S.,
RA Town C.D.;
RT "Araport11: a complete reannotation of the Arabidopsis thaliana reference
RT genome.";
RL Plant J. 89:789-804(2017).
RN [3]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=11910074; DOI=10.1126/science.1071006;
RA Seki M., Narusaka M., Kamiya A., Ishida J., Satou M., Sakurai T.,
RA Nakajima M., Enju A., Akiyama K., Oono Y., Muramatsu M., Hayashizaki Y.,
RA Kawai J., Carninci P., Itoh M., Ishii Y., Arakawa T., Shibata K.,
RA Shinagawa A., Shinozaki K.;
RT "Functional annotation of a full-length Arabidopsis cDNA collection.";
RL Science 296:141-145(2002).
RN [4]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=cv. Columbia;
RX PubMed=14593172; DOI=10.1126/science.1088305;
RA Yamada K., Lim J., Dale J.M., Chen H., Shinn P., Palm C.J., Southwick A.M.,
RA Wu H.C., Kim C.J., Nguyen M., Pham P.K., Cheuk R.F., Karlin-Newmann G.,
RA Liu S.X., Lam B., Sakano H., Wu T., Yu G., Miranda M., Quach H.L.,
RA Tripp M., Chang C.H., Lee J.M., Toriumi M.J., Chan M.M., Tang C.C.,
RA Onodera C.S., Deng J.M., Akiyama K., Ansari Y., Arakawa T., Banh J.,
RA Banno F., Bowser L., Brooks S.Y., Carninci P., Chao Q., Choy N., Enju A.,
RA Goldsmith A.D., Gurjal M., Hansen N.F., Hayashizaki Y., Johnson-Hopson C.,
RA Hsuan V.W., Iida K., Karnes M., Khan S., Koesema E., Ishida J., Jiang P.X.,
RA Jones T., Kawai J., Kamiya A., Meyers C., Nakajima M., Narusaka M.,
RA Seki M., Sakurai T., Satou M., Tamse R., Vaysberg M., Wallender E.K.,
RA Wong C., Yamamura Y., Yuan S., Shinozaki K., Davis R.W., Theologis A.,
RA Ecker J.R.;
RT "Empirical analysis of transcriptional activity in the Arabidopsis
RT genome.";
RL Science 302:842-846(2003).
CC -!- FUNCTION: Involved in the transport of copper. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Membrane {ECO:0000305}; Multi-pass membrane
CC protein {ECO:0000305}.
CC -!- SIMILARITY: Belongs to the copper transporter (Ctr) (TC 1.A.56) family.
CC SLC31A subfamily. {ECO:0000305}.
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DR EMBL; AC005623; -; NOT_ANNOTATED_CDS; Genomic_DNA.
DR EMBL; CP002685; AEC07914.1; -; Genomic_DNA.
DR EMBL; AK118724; BAC43318.1; -; mRNA.
DR EMBL; BT004940; AAO50473.1; -; mRNA.
DR RefSeq; NP_850091.1; NM_179760.3.
DR AlphaFoldDB; Q8GWP3; -.
DR SMR; Q8GWP3; -.
DR BioGRID; 2591; 3.
DR IntAct; Q8GWP3; 2.
DR STRING; 3702.AT2G26975.1; -.
DR TCDB; 1.A.56.1.14; the copper transporter (ctr) family.
DR PaxDb; Q8GWP3; -.
DR PRIDE; Q8GWP3; -.
DR ProteomicsDB; 241174; -.
DR EnsemblPlants; AT2G26975.1; AT2G26975.1; AT2G26975.
DR GeneID; 817239; -.
DR Gramene; AT2G26975.1; AT2G26975.1; AT2G26975.
DR KEGG; ath:AT2G26975; -.
DR Araport; AT2G26975; -.
DR TAIR; locus:504955951; AT2G26975.
DR eggNOG; KOG3386; Eukaryota.
DR HOGENOM; CLU_079690_1_2_1; -.
DR InParanoid; Q8GWP3; -.
DR OMA; HRKMMMH; -.
DR OrthoDB; 1389393at2759; -.
DR PhylomeDB; Q8GWP3; -.
DR PRO; PR:Q8GWP3; -.
DR Proteomes; UP000006548; Chromosome 2.
DR ExpressionAtlas; Q8GWP3; baseline and differential.
DR GO; GO:0016021; C:integral component of membrane; IEA:UniProtKB-KW.
DR GO; GO:0000325; C:plant-type vacuole; HDA:TAIR.
DR GO; GO:0005886; C:plasma membrane; IDA:TAIR.
DR GO; GO:0005375; F:copper ion transmembrane transporter activity; IGI:TAIR.
DR GO; GO:0006878; P:cellular copper ion homeostasis; IBA:GO_Central.
DR GO; GO:0035434; P:copper ion transmembrane transport; IGI:TAIR.
DR InterPro; IPR007274; Cop_transporter.
DR PANTHER; PTHR12483; PTHR12483; 1.
DR Pfam; PF04145; Ctr; 2.
PE 2: Evidence at transcript level;
KW Copper; Copper transport; Ion transport; Membrane; Reference proteome;
KW Transmembrane; Transmembrane helix; Transport.
FT CHAIN 1..145
FT /note="Copper transporter 6"
FT /id="PRO_0000399997"
FT TRANSMEM 47..67
FT /note="Helical"
FT /evidence="ECO:0000255"
FT TRANSMEM 99..119
FT /note="Helical"
FT /evidence="ECO:0000255"
SQ SEQUENCE 145 AA; 15806 MW; 3617487C08EF0C92 CRC64;
MDHGNMPPSS PSSMVNHTNS NMIMMHMTFF WGKNTEILFS GWPGTSLGMY VLCLIVVFLL
AVIVEWLAHS SILRGRGSTS RAKGLVQTAV YTLKTGLAYL VMLAVMSFNG GVFIVAIAGF
AVGFMLFGST AFKNPSDDEK PFEQL
