COQ10_ASHGO
ID COQ10_ASHGO Reviewed; 204 AA.
AC Q75CC1;
DT 21-MAR-2006, integrated into UniProtKB/Swiss-Prot.
DT 05-JUL-2004, sequence version 1.
DT 25-MAY-2022, entry version 98.
DE RecName: Full=Coenzyme Q-binding protein COQ10, mitochondrial;
DE Flags: Precursor;
GN Name=COQ10; OrderedLocusNames=ACL012W;
OS Ashbya gossypii (strain ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056)
OS (Yeast) (Eremothecium gossypii).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Saccharomycotina; Saccharomycetes;
OC Saccharomycetales; Saccharomycetaceae; Eremothecium.
OX NCBI_TaxID=284811;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=15001715; DOI=10.1126/science.1095781;
RA Dietrich F.S., Voegeli S., Brachat S., Lerch A., Gates K., Steiner S.,
RA Mohr C., Poehlmann R., Luedi P., Choi S., Wing R.A., Flavier A.,
RA Gaffney T.D., Philippsen P.;
RT "The Ashbya gossypii genome as a tool for mapping the ancient Saccharomyces
RT cerevisiae genome.";
RL Science 304:304-307(2004).
RN [2]
RP GENOME REANNOTATION.
RC STRAIN=ATCC 10895 / CBS 109.51 / FGSC 9923 / NRRL Y-1056;
RX PubMed=23749448; DOI=10.1534/g3.112.002881;
RA Dietrich F.S., Voegeli S., Kuo S., Philippsen P.;
RT "Genomes of Ashbya fungi isolated from insects reveal four mating-type
RT loci, numerous translocations, lack of transposons, and distinct gene
RT duplications.";
RL G3 (Bethesda) 3:1225-1239(2013).
CC -!- FUNCTION: Required for the function of coenzyme Q in the respiratory
CC chain. May serve as a chaperone or may be involved in the transport of
CC Q6 from its site of synthesis to the catalytic sites of the respiratory
CC complexes (By similarity). {ECO:0000250}.
CC -!- SUBUNIT: Interacts with coenzyme Q. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the COQ10 family. {ECO:0000305}.
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DR EMBL; AE016816; AAS51216.1; -; Genomic_DNA.
DR RefSeq; NP_983392.1; NM_208745.1.
DR AlphaFoldDB; Q75CC1; -.
DR SMR; Q75CC1; -.
DR STRING; 33169.AAS51216; -.
DR EnsemblFungi; AAS51216; AAS51216; AGOS_ACL012W.
DR GeneID; 4619517; -.
DR KEGG; ago:AGOS_ACL012W; -.
DR eggNOG; KOG3177; Eukaryota.
DR HOGENOM; CLU_079653_1_2_1; -.
DR InParanoid; Q75CC1; -.
DR OMA; HEFIPYC; -.
DR Proteomes; UP000000591; Chromosome III.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0048039; F:ubiquinone binding; IBA:GO_Central.
DR GO; GO:0045333; P:cellular respiration; IBA:GO_Central.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IBA:GO_Central.
DR CDD; cd07813; COQ10p_like; 1.
DR Gene3D; 3.30.530.20; -; 1.
DR InterPro; IPR044996; COQ10-like.
DR InterPro; IPR005031; COQ10_START.
DR InterPro; IPR023393; START-like_dom_sf.
DR PANTHER; PTHR12901; PTHR12901; 1.
DR Pfam; PF03364; Polyketide_cyc; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transit peptide.
FT TRANSIT 1..24
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 25..204
FT /note="Coenzyme Q-binding protein COQ10, mitochondrial"
FT /id="PRO_0000227687"
SQ SEQUENCE 204 AA; 23309 MW; 6691B8C53A8F6B8D CRC64;
MLRCLISRPQ LLPTRLPLAT PSCVSRRTFL GFTGGDTKEQ RYILKRVFNA PLHYVYPAVS
EVSLYKLFIP YCTDSFVNKR RPGDNMPTEA GLRVGFQQYD ETFVCRVDCT TLPGNQRSVV
AESLAHHLFE TLHTQWLLSP HPTRPDASVV ELILRFKFKS QLYNSVSSIF GTRVTQVVMK
AFEKRVFQLR KEAMDRPPTG DAGH
