ID   COQ10_DICDI             Reviewed;         205 AA.
AC   Q556V1; Q86JV6;
DT   08-APR-2008, integrated into UniProtKB/Swiss-Prot.
DT   02-MAY-2006, sequence version 1.
DT   25-MAY-2022, entry version 73.
DE   RecName: Full=Coenzyme Q-binding protein COQ10, mitochondrial;
DE   Flags: Precursor;
GN   Name=coq10-1; ORFNames=DDB_G0273089;
GN   and
GN   Name=coq10-2; ORFNames=DDB_G0273803;
OS   Dictyostelium discoideum (Slime mold).
OC   Eukaryota; Amoebozoa; Evosea; Eumycetozoa; Dictyostelia; Dictyosteliales;
OC   Dictyosteliaceae; Dictyostelium.
OX   NCBI_TaxID=44689;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=12097910; DOI=10.1038/nature00847;
RA   Gloeckner G., Eichinger L., Szafranski K., Pachebat J.A., Bankier A.T.,
RA   Dear P.H., Lehmann R., Baumgart C., Parra G., Abril J.F., Guigo R.,
RA   Kumpf K., Tunggal B., Cox E.C., Quail M.A., Platzer M., Rosenthal A.,
RA   Noegel A.A.;
RT   "Sequence and analysis of chromosome 2 of Dictyostelium discoideum.";
RL   Nature 418:79-85(2002).
RN   [2]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=AX4;
RX   PubMed=15875012; DOI=10.1038/nature03481;
RA   Eichinger L., Pachebat J.A., Gloeckner G., Rajandream M.A., Sucgang R.,
RA   Berriman M., Song J., Olsen R., Szafranski K., Xu Q., Tunggal B.,
RA   Kummerfeld S., Madera M., Konfortov B.A., Rivero F., Bankier A.T.,
RA   Lehmann R., Hamlin N., Davies R., Gaudet P., Fey P., Pilcher K., Chen G.,
RA   Saunders D., Sodergren E.J., Davis P., Kerhornou A., Nie X., Hall N.,
RA   Anjard C., Hemphill L., Bason N., Farbrother P., Desany B., Just E.,
RA   Morio T., Rost R., Churcher C.M., Cooper J., Haydock S., van Driessche N.,
RA   Cronin A., Goodhead I., Muzny D.M., Mourier T., Pain A., Lu M., Harper D.,
RA   Lindsay R., Hauser H., James K.D., Quiles M., Madan Babu M., Saito T.,
RA   Buchrieser C., Wardroper A., Felder M., Thangavelu M., Johnson D.,
RA   Knights A., Loulseged H., Mungall K.L., Oliver K., Price C., Quail M.A.,
RA   Urushihara H., Hernandez J., Rabbinowitsch E., Steffen D., Sanders M.,
RA   Ma J., Kohara Y., Sharp S., Simmonds M.N., Spiegler S., Tivey A.,
RA   Sugano S., White B., Walker D., Woodward J.R., Winckler T., Tanaka Y.,
RA   Shaulsky G., Schleicher M., Weinstock G.M., Rosenthal A., Cox E.C.,
RA   Chisholm R.L., Gibbs R.A., Loomis W.F., Platzer M., Kay R.R.,
RA   Williams J.G., Dear P.H., Noegel A.A., Barrell B.G., Kuspa A.;
RT   "The genome of the social amoeba Dictyostelium discoideum.";
RL   Nature 435:43-57(2005).
CC   -!- FUNCTION: Required for the function of coenzyme Q in the respiratory
CC       chain. May serve as a chaperone or may be involved in the transport of
CC       Q6 from its site of synthesis to the catalytic sites of the respiratory
CC       complexes (By similarity). {ECO:0000250}.
CC   -!- SUBUNIT: Interacts with coenzyme Q. {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COQ10 family. {ECO:0000305}.
CC   -!- CAUTION: The gene for this protein is duplicated in strains AX3 and
CC       AX4. These strains contain a duplication of a segment of 750 kb of
CC       chromosome 2 compared to the corresponding sequence in strain AX2.
CC       {ECO:0000305}.
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DR   EMBL; AAFI02000011; EAL70592.1; -; Genomic_DNA.
DR   EMBL; AAFI02000009; EAL70762.1; -; Genomic_DNA.
DR   RefSeq; XP_644518.1; XM_639426.1.
DR   RefSeq; XP_644732.1; XM_639640.1.
DR   AlphaFoldDB; Q556V1; -.
DR   SMR; Q556V1; -.
DR   STRING; 44689.DDB0266670; -.
DR   PaxDb; Q556V1; -.
DR   EnsemblProtists; EAL70592; EAL70592; DDB_G0273803.
DR   EnsemblProtists; EAL70762; EAL70762; DDB_G0273089.
DR   GeneID; 8618832; -.
DR   GeneID; 8619144; -.
DR   KEGG; ddi:DDB_G0273089; -.
DR   KEGG; ddi:DDB_G0273803; -.
DR   dictyBase; DDB_G0273089; coq10-1.
DR   dictyBase; DDB_G0273803; coq10-2.
DR   eggNOG; KOG3177; Eukaryota.
DR   HOGENOM; CLU_079653_1_2_1; -.
DR   InParanoid; Q556V1; -.
DR   OMA; YIDGPFK; -.
DR   PhylomeDB; Q556V1; -.
DR   PRO; PR:Q556V1; -.
DR   Proteomes; UP000002195; Chromosome 2.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0005739; C:mitochondrion; ISS:dictyBase.
DR   GO; GO:0048039; F:ubiquinone binding; ISS:dictyBase.
DR   GO; GO:0045333; P:cellular respiration; IBA:GO_Central.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IBA:GO_Central.
DR   CDD; cd07813; COQ10p_like; 1.
DR   Gene3D; 3.30.530.20; -; 1.
DR   InterPro; IPR044996; COQ10-like.
DR   InterPro; IPR005031; COQ10_START.
DR   InterPro; IPR023393; START-like_dom_sf.
DR   PANTHER; PTHR12901; PTHR12901; 1.
DR   Pfam; PF03364; Polyketide_cyc; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Transit peptide.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..205
FT                   /note="Coenzyme Q-binding protein COQ10, mitochondrial"
FT                   /id="PRO_0000328287"
SQ   SEQUENCE   205 AA;  23681 MW;  2369F50D6B4A8516 CRC64;
     MIKYSNLVIP KTKSILKSGC NNNIGYGDRY FFNKLFGSND ASDTHNQPTT KIVTKEMTKE
     LKYPVNQVYS VIIKVEDYKE FLPFCLNSTI LKREKDKNHF EAELEVGQGT IKESYVSKVV
     YKENKFIEST ATDTPLFHKL INTWSFKQGQ TPNTTIAHCK LIYQFKSPFY ATLMENFFAS
     SLDVMINSFD KRCDELYGSS NSFKK