ID   COQ42_PARTE             Reviewed;         209 AA.
AC   A0E513;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   28-NOV-2006, sequence version 1.
DT   25-MAY-2022, entry version 56.
DE   RecName: Full=Ubiquinone biosynthesis protein COQ4 homolog 2, mitochondrial;
DE   AltName: Full=Coenzyme Q biosynthesis protein 4 homolog 2 {ECO:0000255|HAMAP-Rule:MF_03111};
GN   ORFNames=GSPATT00023557001;
OS   Paramecium tetraurelia.
OC   Eukaryota; Sar; Alveolata; Ciliophora; Intramacronucleata;
OC   Oligohymenophorea; Peniculida; Parameciidae; Paramecium.
OX   NCBI_TaxID=5888;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Stock d4-2;
RX   PubMed=17086204; DOI=10.1038/nature05230;
RA   Aury J.-M., Jaillon O., Duret L., Noel B., Jubin C., Porcel B.M.,
RA   Segurens B., Daubin V., Anthouard V., Aiach N., Arnaiz O., Billaut A.,
RA   Beisson J., Blanc I., Bouhouche K., Camara F., Duharcourt S., Guigo R.,
RA   Gogendeau D., Katinka M., Keller A.-M., Kissmehl R., Klotz C., Koll F.,
RA   Le Mouel A., Lepere G., Malinsky S., Nowacki M., Nowak J.K., Plattner H.,
RA   Poulain J., Ruiz F., Serrano V., Zagulski M., Dessen P., Betermier M.,
RA   Weissenbach J., Scarpelli C., Schaechter V., Sperling L., Meyer E.,
RA   Cohen J., Wincker P.;
RT   "Global trends of whole-genome duplications revealed by the ciliate
RT   Paramecium tetraurelia.";
RL   Nature 444:171-178(2006).
CC   -!- FUNCTION: Component of the coenzyme Q biosynthetic pathway. May play a
CC       role in organizing a multi-subunit COQ enzyme complex required for
CC       coenzyme Q biosynthesis. Required for steady-state levels of other COQ
CC       polypeptides. {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- SUBUNIT: Component of a multi-subunit COQ enzyme complex.
CC       {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_03111}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_03111}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- MISCELLANEOUS: This protein may be expected to contain an N-terminal
CC       transit peptide but none has been predicted. {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
CC   -!- SIMILARITY: Belongs to the COQ4 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
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DR   EMBL; CT868659; CAK90380.1; -; Genomic_DNA.
DR   RefSeq; XP_001457777.1; XM_001457740.1.
DR   AlphaFoldDB; A0E513; -.
DR   SMR; A0E513; -.
DR   STRING; 5888.CAK90380; -.
DR   PRIDE; A0E513; -.
DR   EnsemblProtists; CAK90380; CAK90380; GSPATT00023557001.
DR   GeneID; 5043562; -.
DR   KEGG; ptm:GSPATT00023557001; -.
DR   eggNOG; KOG3244; Eukaryota.
DR   HOGENOM; CLU_061241_1_1_1; -.
DR   InParanoid; A0E513; -.
DR   OMA; KFFEFAN; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000000600; Partially assembled WGS sequence.
DR   GO; GO:0031314; C:extrinsic component of mitochondrial inner membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_03111; Coq4; 1.
DR   InterPro; IPR007715; Coq4.
DR   InterPro; IPR027540; Coq4_euk.
DR   PANTHER; PTHR12922; PTHR12922; 1.
DR   Pfam; PF05019; Coq4; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Ubiquinone biosynthesis.
FT   CHAIN           1..209
FT                   /note="Ubiquinone biosynthesis protein COQ4 homolog 2,
FT                   mitochondrial"
FT                   /id="PRO_0000388077"
SQ   SEQUENCE   209 AA;  24774 MW;  50868B09DC66C62B CRC64;
     MRHQCIQIPF KVNLLNKYFI SGNHLSQLGE LSGYYCVKDI HQRMLQHPIG QRILNDKPRV
     TPQTFKIEEL LKLDENTFGH QYGKFMKDRD FSSGERPIVK YIPDLELAYV YQRYKEIHDF
     IHVLLMYDVS VYDEIVVKWF EMAQLGLPSA TLSAFVGSFK LNCQEKQKLM ETLPQILKRA
     HKSEFIMNVY FEEHINTDIT QLRKSLRLL