COQ4_BOVIN
ID COQ4_BOVIN Reviewed; 151 AA.
AC Q05B52;
DT 03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 14-NOV-2006, sequence version 1.
DT 25-MAY-2022, entry version 58.
DE RecName: Full=Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial;
DE AltName: Full=Coenzyme Q biosynthesis protein 4 homolog;
DE Flags: Precursor;
GN Name=COQ4;
OS Bos taurus (Bovine).
OC Eukaryota; Metazoa; Chordata; Craniata; Vertebrata; Euteleostomi; Mammalia;
OC Eutheria; Laurasiatheria; Artiodactyla; Ruminantia; Pecora; Bovidae;
OC Bovinae; Bos.
OX NCBI_TaxID=9913;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE MRNA].
RC STRAIN=Hereford; TISSUE=Hypothalamus;
RG NIH - Mammalian Gene Collection (MGC) project;
RL Submitted (AUG-2006) to the EMBL/GenBank/DDBJ databases.
CC -!- FUNCTION: Component of the coenzyme Q biosynthetic pathway. May play a
CC role in organizing a multi-subunit COQ enzyme complex required for
CC coenzyme Q biosynthesis. Required for steady-state levels of other COQ
CC polypeptides (By similarity). {ECO:0000250}.
CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC -!- SUBUNIT: Component of a multi-subunit COQ enzyme complex, composed of
CC at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. {ECO:0000250}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC -!- SIMILARITY: Belongs to the COQ4 family. {ECO:0000305}.
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DR EMBL; BC122805; AAI22806.1; -; mRNA.
DR RefSeq; NP_001077141.1; NM_001083672.2.
DR AlphaFoldDB; Q05B52; -.
DR STRING; 9913.ENSBTAP00000053835; -.
DR GeneID; 511987; -.
DR KEGG; bta:511987; -.
DR CTD; 51117; -.
DR InParanoid; Q05B52; -.
DR OrthoDB; 1264469at2759; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000009136; Unplaced.
DR GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR InterPro; IPR007715; Coq4.
DR PANTHER; PTHR12922; PTHR12922; 1.
DR Pfam; PF05019; Coq4; 1.
PE 2: Evidence at transcript level;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Phosphoprotein;
KW Reference proteome; Transit peptide; Ubiquinone biosynthesis.
FT TRANSIT 1..29
FT /note="Mitochondrion"
FT /evidence="ECO:0000255"
FT CHAIN 30..151
FT /note="Ubiquinone biosynthesis protein COQ4 homolog,
FT mitochondrial"
FT /id="PRO_0000388052"
FT MOD_RES 108
FT /note="Phosphoserine"
FT /evidence="ECO:0000250|UniProtKB:Q9Y3A0"
SQ SEQUENCE 151 AA; 16337 MW; 5759CCF6C4605896 CRC64;
MATLLRGVLR PLCAFRGGPG PPAGVPFRAV SHGTGLLYPE HIPTSVLQKV LLAAGSAGMA
LYDPYRHDMV AVLGETTGRR TLKVLRDQMK RDPEGAQILQ ERPRISLSTL DMGKLRSLPE
GSFGCAYLHF LDVNVASGRG MTVCTEDFIQ C