ID   COQ4_CRYHO              Reviewed;         155 AA.
AC   Q5CHB0;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   12-APR-2005, sequence version 1.
DT   25-MAY-2022, entry version 51.
DE   RecName: Full=Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial;
DE   AltName: Full=Coenzyme Q biosynthesis protein 4 homolog;
DE   Flags: Precursor;
GN   ORFNames=Chro.10049;
OS   Cryptosporidium hominis.
OC   Eukaryota; Sar; Alveolata; Apicomplexa; Conoidasida; Coccidia;
OC   Eucoccidiorida; Eimeriorina; Cryptosporidiidae; Cryptosporidium.
OX   NCBI_TaxID=237895;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=TU502;
RX   PubMed=15510150; DOI=10.1038/nature02977;
RA   Xu P., Widmer G., Wang Y., Ozaki L.S., Alves J.M., Serrano M.G., Puiu D.,
RA   Manque P., Akiyoshi D., Mackey A.J., Pearson W.R., Dear P.H., Bankier A.T.,
RA   Peterson D.L., Abrahamsen M.S., Kapur V., Tzipori S., Buck G.A.;
RT   "The genome of Cryptosporidium hominis.";
RL   Nature 431:1107-1112(2004).
CC   -!- FUNCTION: Component of the coenzyme Q biosynthetic pathway. May play a
CC       role in organizing a multi-subunit COQ enzyme complex required for
CC       coenzyme Q biosynthesis. Required for steady-state levels of other COQ
CC       polypeptides (By similarity). {ECO:0000250}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC   -!- SUBUNIT: Component of a multi-subunit COQ enzyme complex.
CC       {ECO:0000250}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000250};
CC       Peripheral membrane protein {ECO:0000250}; Matrix side {ECO:0000250}.
CC   -!- SIMILARITY: Belongs to the COQ4 family. {ECO:0000305}.
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DR   EMBL; AAEL01000257; EAL35992.1; -; Genomic_DNA.
DR   RefSeq; XP_666228.1; XM_661136.1.
DR   AlphaFoldDB; Q5CHB0; -.
DR   SMR; Q5CHB0; -.
DR   GeneID; 3412928; -.
DR   KEGG; cho:Chro.10049; -.
DR   VEuPathDB; CryptoDB:Chro.10049; -.
DR   VEuPathDB; CryptoDB:ChTU502y2012_302g0190; -.
DR   VEuPathDB; CryptoDB:CHUDEA1_380; -.
DR   VEuPathDB; CryptoDB:GY17_00001035; -.
DR   InParanoid; Q5CHB0; -.
DR   UniPathway; UPA00232; -.
DR   GO; GO:0005743; C:mitochondrial inner membrane; IEA:UniProtKB-SubCell.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniPathway.
DR   InterPro; IPR007715; Coq4.
DR   PANTHER; PTHR12922; PTHR12922; 1.
DR   Pfam; PF05019; Coq4; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Transit peptide;
KW   Ubiquinone biosynthesis.
FT   TRANSIT         1..?
FT                   /note="Mitochondrion"
FT                   /evidence="ECO:0000255"
FT   CHAIN           ?..155
FT                   /note="Ubiquinone biosynthesis protein COQ4 homolog,
FT                   mitochondrial"
FT                   /id="PRO_0000388074"
SQ   SEQUENCE   155 AA;  17839 MW;  2E5A485F8F21036C CRC64;
     MNKFTNLLIK RTASSLKGGD FRELFRKNYI PITQFEKVLL SVTSCVEGLK NPTDSNSVAC
     ITELTSNRAL RKLQILMNST PDGRRIIKNR PLIDSSKYSI KDLMAFPDDS LGRRYGEFLT
     TYNLEIDRAP VRYVNSEDLA YVLTRFRQVS LNDYK