ID   COQ4_DROAN              Reviewed;         266 AA.
AC   B3M6C8;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-SEP-2008, sequence version 1.
DT   03-AUG-2022, entry version 66.
DE   RecName: Full=Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03111};
DE   AltName: Full=Coenzyme Q biosynthesis protein 4 homolog {ECO:0000255|HAMAP-Rule:MF_03111};
GN   ORFNames=GF24309;
OS   Drosophila ananassae (Fruit fly).
OC   Eukaryota; Metazoa; Ecdysozoa; Arthropoda; Hexapoda; Insecta; Pterygota;
OC   Neoptera; Endopterygota; Diptera; Brachycera; Muscomorpha; Ephydroidea;
OC   Drosophilidae; Drosophila; Sophophora.
OX   NCBI_TaxID=7217;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=Tucson 14024-0371.13;
RX   PubMed=17994087; DOI=10.1038/nature06341;
RG   Drosophila 12 genomes consortium;
RT   "Evolution of genes and genomes on the Drosophila phylogeny.";
RL   Nature 450:203-218(2007).
CC   -!- FUNCTION: Component of the coenzyme Q biosynthetic pathway. May play a
CC       role in organizing a multi-subunit COQ enzyme complex required for
CC       coenzyme Q biosynthesis. Required for steady-state levels of other COQ
CC       polypeptides. {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- SUBUNIT: Component of a multi-subunit COQ enzyme complex.
CC       {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_03111}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_03111}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- MISCELLANEOUS: This protein may be expected to contain an N-terminal
CC       transit peptide but none has been predicted. {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
CC   -!- SIMILARITY: Belongs to the COQ4 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
CC   ---------------------------------------------------------------------------
CC   Copyrighted by the UniProt Consortium, see https://www.uniprot.org/terms
CC   Distributed under the Creative Commons Attribution (CC BY 4.0) License
CC   ---------------------------------------------------------------------------
DR   EMBL; CH902618; EDV39748.1; -; Genomic_DNA.
DR   RefSeq; XP_001956942.1; XM_001956906.2.
DR   RefSeq; XP_014764981.1; XM_014909495.1.
DR   AlphaFoldDB; B3M6C8; -.
DR   SMR; B3M6C8; -.
DR   STRING; 7217.FBpp0127501; -.
DR   PRIDE; B3M6C8; -.
DR   EnsemblMetazoa; FBtr0129009; FBpp0127501; FBgn0101303.
DR   EnsemblMetazoa; FBtr0391179; FBpp0350650; FBgn0101303.
DR   GeneID; 6506942; -.
DR   KEGG; dan:6506942; -.
DR   eggNOG; KOG3244; Eukaryota.
DR   HOGENOM; CLU_061241_1_1_1; -.
DR   InParanoid; B3M6C8; -.
DR   OMA; KFFEFAN; -.
DR   OrthoDB; 1264469at2759; -.
DR   PhylomeDB; B3M6C8; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000007801; Unassembled WGS sequence.
DR   GO; GO:0031314; C:extrinsic component of mitochondrial inner membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_03111; Coq4; 1.
DR   InterPro; IPR007715; Coq4.
DR   InterPro; IPR027540; Coq4_euk.
DR   PANTHER; PTHR12922; PTHR12922; 1.
DR   Pfam; PF05019; Coq4; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Ubiquinone biosynthesis.
FT   CHAIN           1..266
FT                   /note="Ubiquinone biosynthesis protein COQ4 homolog,
FT                   mitochondrial"
FT                   /id="PRO_0000388061"
SQ   SEQUENCE   266 AA;  30229 MW;  EB19982573AB5BF9 CRC64;
     MMQRCVWRLQ MPLALRRGLA SGEAKNQGVS PEAEPLDSFE RQYLKDRIEI SPFQRVILGA
     GSSIAALLDP RRHDMIACLG ETTGEGALEN ILDTMQASEE GQRIMAEKPR IHTSTIDFKL
     LESLPADSFG AAYVKFLKDN QVTPDSRMAV RFLEDPKLAY LMTRYRECHD LIHTVLGMPT
     NMLGEVAVKW VEALNTGLPM CYGGAVFGAV RLRPKQRRAY LKHYLPWALE NGKRSKPLMP
     VYWEKRWEQK LQDLRAELGI TVLNKV