ID   COQ4_NEMVE              Reviewed;         208 AA.
AC   A7SNR3;
DT   03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT   02-OCT-2007, sequence version 1.
DT   25-MAY-2022, entry version 69.
DE   RecName: Full=Ubiquinone biosynthesis protein COQ4 homolog, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03111};
DE   AltName: Full=Coenzyme Q biosynthesis protein 4 homolog {ECO:0000255|HAMAP-Rule:MF_03111};
GN   ORFNames=v1g191789;
OS   Nematostella vectensis (Starlet sea anemone).
OC   Eukaryota; Metazoa; Cnidaria; Anthozoa; Hexacorallia; Actiniaria;
OC   Edwardsiidae; Nematostella.
OX   NCBI_TaxID=45351;
RN   [1]
RP   NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC   STRAIN=CH2 X CH6;
RX   PubMed=17615350; DOI=10.1126/science.1139158;
RA   Putnam N.H., Srivastava M., Hellsten U., Dirks B., Chapman J., Salamov A.,
RA   Terry A., Shapiro H., Lindquist E., Kapitonov V.V., Jurka J.,
RA   Genikhovich G., Grigoriev I.V., Lucas S.M., Steele R.E., Finnerty J.R.,
RA   Technau U., Martindale M.Q., Rokhsar D.S.;
RT   "Sea anemone genome reveals ancestral eumetazoan gene repertoire and
RT   genomic organization.";
RL   Science 317:86-94(2007).
CC   -!- FUNCTION: Component of the coenzyme Q biosynthetic pathway. May play a
CC       role in organizing a multi-subunit COQ enzyme complex required for
CC       coenzyme Q biosynthesis. Required for steady-state levels of other COQ
CC       polypeptides. {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC       {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- SUBUNIT: Component of a multi-subunit COQ enzyme complex.
CC       {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000255|HAMAP-
CC       Rule:MF_03111}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC       Rule:MF_03111}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03111}.
CC   -!- MISCELLANEOUS: This protein may be expected to contain an N-terminal
CC       transit peptide but none has been predicted. {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
CC   -!- SIMILARITY: Belongs to the COQ4 family. {ECO:0000255|HAMAP-
CC       Rule:MF_03111}.
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DR   EMBL; DS469723; EDO34664.1; -; Genomic_DNA.
DR   RefSeq; XP_001626764.1; XM_001626714.1.
DR   AlphaFoldDB; A7SNR3; -.
DR   SMR; A7SNR3; -.
DR   STRING; 45351.EDO34664; -.
DR   PRIDE; A7SNR3; -.
DR   EnsemblMetazoa; EDO34664; EDO34664; NEMVEDRAFT_v1g191789.
DR   GeneID; 5506011; -.
DR   KEGG; nve:5506011; -.
DR   eggNOG; KOG3244; Eukaryota.
DR   HOGENOM; CLU_061241_1_1_1; -.
DR   InParanoid; A7SNR3; -.
DR   OMA; KFFEFAN; -.
DR   OrthoDB; 1264469at2759; -.
DR   PhylomeDB; A7SNR3; -.
DR   UniPathway; UPA00232; -.
DR   Proteomes; UP000001593; Unassembled WGS sequence.
DR   GO; GO:0031314; C:extrinsic component of mitochondrial inner membrane; IEA:UniProtKB-UniRule.
DR   GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR   GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR   HAMAP; MF_03111; Coq4; 1.
DR   InterPro; IPR007715; Coq4.
DR   InterPro; IPR027540; Coq4_euk.
DR   PANTHER; PTHR12922; PTHR12922; 1.
DR   Pfam; PF05019; Coq4; 1.
PE   3: Inferred from homology;
KW   Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW   Ubiquinone biosynthesis.
FT   CHAIN           1..208
FT                   /note="Ubiquinone biosynthesis protein COQ4 homolog,
FT                   mitochondrial"
FT                   /id="PRO_0000388072"
SQ   SEQUENCE   208 AA;  24298 MW;  292D73A7A6EB1A39 CRC64;
     MALYNPYRSD MVATLGETTG FVARQLMLYR MKQDPVGREI LRLQPRVKSW TVDLNEMRSL
     QEGTFGREYA RFMDDNGLDQ DSRDDVKFVD DIELAYVMQR YRDIHDFTHT LTGLPTVSVA
     GEIAVKWFEM VQTGLPMCTL GSIFGPLNPE VTPKHREQLR SYYIPWALSN GMKAKFIMNV
     FYERHFEEPI DSLRKKMNLT PARRLDGW