COQ4_PHANO
ID COQ4_PHANO Reviewed; 290 AA.
AC Q0V6R0;
DT 03-NOV-2009, integrated into UniProtKB/Swiss-Prot.
DT 03-NOV-2009, sequence version 3.
DT 25-MAY-2022, entry version 59.
DE RecName: Full=Ubiquinone biosynthesis protein COQ4, mitochondrial {ECO:0000255|HAMAP-Rule:MF_03111};
DE AltName: Full=Coenzyme Q biosynthesis protein 4 {ECO:0000255|HAMAP-Rule:MF_03111};
DE Flags: Precursor;
GN Name=COQ4 {ECO:0000255|HAMAP-Rule:MF_03111}; ORFNames=SNOG_00304;
OS Phaeosphaeria nodorum (strain SN15 / ATCC MYA-4574 / FGSC 10173) (Glume
OS blotch fungus) (Parastagonospora nodorum).
OC Eukaryota; Fungi; Dikarya; Ascomycota; Pezizomycotina; Dothideomycetes;
OC Pleosporomycetidae; Pleosporales; Pleosporineae; Phaeosphaeriaceae;
OC Parastagonospora.
OX NCBI_TaxID=321614;
RN [1]
RP NUCLEOTIDE SEQUENCE [LARGE SCALE GENOMIC DNA].
RC STRAIN=SN15 / ATCC MYA-4574 / FGSC 10173;
RX PubMed=18024570; DOI=10.1105/tpc.107.052829;
RA Hane J.K., Lowe R.G.T., Solomon P.S., Tan K.-C., Schoch C.L.,
RA Spatafora J.W., Crous P.W., Kodira C.D., Birren B.W., Galagan J.E.,
RA Torriani S.F.F., McDonald B.A., Oliver R.P.;
RT "Dothideomycete-plant interactions illuminated by genome sequencing and EST
RT analysis of the wheat pathogen Stagonospora nodorum.";
RL Plant Cell 19:3347-3368(2007).
CC -!- FUNCTION: Component of the coenzyme Q biosynthetic pathway. May play a
CC role in organizing a multi-subunit COQ enzyme complex required for
CC coenzyme Q biosynthesis. Required for steady-state levels of other COQ
CC polypeptides. {ECO:0000255|HAMAP-Rule:MF_03111}.
CC -!- PATHWAY: Cofactor biosynthesis; ubiquinone biosynthesis.
CC {ECO:0000255|HAMAP-Rule:MF_03111}.
CC -!- SUBUNIT: Component of a multi-subunit COQ enzyme complex, composed of
CC at least COQ3, COQ4, COQ5, COQ6, COQ7 and COQ9. {ECO:0000255|HAMAP-
CC Rule:MF_03111}.
CC -!- SUBCELLULAR LOCATION: Mitochondrion inner membrane {ECO:0000255|HAMAP-
CC Rule:MF_03111}; Peripheral membrane protein {ECO:0000255|HAMAP-
CC Rule:MF_03111}; Matrix side {ECO:0000255|HAMAP-Rule:MF_03111}.
CC -!- SIMILARITY: Belongs to the COQ4 family. {ECO:0000255|HAMAP-
CC Rule:MF_03111}.
CC -!- SEQUENCE CAUTION:
CC Sequence=EAT91799.2; Type=Erroneous gene model prediction; Evidence={ECO:0000305};
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DR EMBL; CH445325; EAT91799.2; ALT_SEQ; Genomic_DNA.
DR RefSeq; XP_001790994.1; XM_001790942.1.
DR AlphaFoldDB; Q0V6R0; -.
DR SMR; Q0V6R0; -.
DR STRING; 13684.SNOT_00304; -.
DR GeneID; 5968059; -.
DR KEGG; pno:SNOG_00304; -.
DR eggNOG; KOG3244; Eukaryota.
DR InParanoid; Q0V6R0; -.
DR OrthoDB; 1264469at2759; -.
DR UniPathway; UPA00232; -.
DR Proteomes; UP000001055; Unassembled WGS sequence.
DR GO; GO:0031314; C:extrinsic component of mitochondrial inner membrane; IEA:UniProtKB-UniRule.
DR GO; GO:0005739; C:mitochondrion; IBA:GO_Central.
DR GO; GO:0006744; P:ubiquinone biosynthetic process; IEA:UniProtKB-UniRule.
DR HAMAP; MF_03111; Coq4; 1.
DR InterPro; IPR007715; Coq4.
DR InterPro; IPR027540; Coq4_euk.
DR PANTHER; PTHR12922; PTHR12922; 1.
DR Pfam; PF05019; Coq4; 1.
PE 3: Inferred from homology;
KW Membrane; Mitochondrion; Mitochondrion inner membrane; Reference proteome;
KW Transit peptide; Ubiquinone biosynthesis.
FT TRANSIT 1..32
FT /note="Mitochondrion"
FT /evidence="ECO:0000255|HAMAP-Rule:MF_03111"
FT CHAIN 33..290
FT /note="Ubiquinone biosynthesis protein COQ4, mitochondrial"
FT /id="PRO_0000388128"
FT REGION 260..290
FT /note="Disordered"
FT /evidence="ECO:0000256|SAM:MobiDB-lite"
SQ SEQUENCE 290 AA; 33122 MW; 91625FA03DEA4751 CRC64;
MAKRVCVGDL RKLAGSVSTP SRCILPPHAR CFSVLNRPPP NYEGHIPLTV IERLGLAVGS
GLGSFLDPRR ADLIASFGEA TAQPHFIYKL RDRMLLNPTG RRILRDRPRL TSTSLDIPRL
RQLPPNTLGY VYALWLDREG VSPDTRATVQ YIDDEECAYV MQRYRECHDF YHALVGLPVF
REGEVALKAF EFANTGLPMT GLAVFSAFTL KKAEWRRFWD IYGPWATRNG AQSDDVINIY
WEEELETDID QLRTRLGIEK PPDLREMRKA EREAQKKDKE AKETMTRAAV
